Volume 11 | Issue 1

 Abstract

The oral thin-film technology is still in the beginning stages and but most popular because it fulfils all the need of patients. In due course, these formulations having APIs will be commercially launched using the oral film technology. These can be prepared using hydrophilic polymers that rapidly dissolves on the tongue or buccal cavity, delivering the drug to the systemic circulation via dissolution when contact with liquid is made. Water-soluble polymers are used as film formers for fast dissolving films. It seems that the value on the whole oral thin film market will grow significantly. The film has the ability to dissolve rapidly without the need for water provides an alternative to the patients receiving swallowing disorder patient suffering from nausea headache etc. Oral thin films (OTFs) are the most advanced and promising new approaches for drug delivery as it offers more flexibility and comfort. These enable an ease of administration, as there is no need to drink high amounts of liquids or swallow large solid dosage forms Also it improves the efficacy of APIs by dissolving within minute in oral cavity after the contact with less saliva as compared to fast dissolving tablets, without chewing and no need of water for administration. OTF offers an alternative to tablets, syrups or suppositories for treatment of vomiting and nausea, especially for the pediatric population.

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oral thin films, hydrophilic polymer, nausea, vomiting

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India largely depend on coals based thermal power, but now world is moving toward renewable energy as coal extinction and over exploitation. Solar energy has the maximum potential to be exploited to the maximum level to full fill the energy demands of the world. The Sun has been worshiped as a life-giver to our planet. About 5,000 trillion kWh energy/year is over India's land area with most parts receiving 4-7 kWh per sq. m/day. Solar energy has become a leading solution to meet the increasing energy demand of growing populations. Solar photovoltaic (PV) technology is an efficient option to generate electricity from solar energy and mitigate climate change. The development and growth of solar photovoltaics has had a positive impact on energy system decarbonization, but end-of-life solar panels might become toxic waste, if not properly disposed. Presently in India, approx. 200,000 tons of solar photovoltaic (PV) waste are expected to be produced by 2030 and 1.8 million tons by 2050 by which time solar waste could grow to 60 million tons globally (Rathore et al, 2022). Solar waste recently included in the category of electrical and electronic equipment waste to restrict the negative impact of continual development. The present focus is only on increasing the efficiency of solar PV panels without considering the impact of waste on the environment. The solar waste management and recovery of components from waste, would prevent the leaching of various toxic elements into the environment. PV module recycling is a multistep process involving dismantling, delamination, and metal recovery. Several techniques are available to recover the intrinsic components in the PV modules, like chemical delamination, yield undamaged solar cells, which could be reused directly or with refurbishing. Mechanical and combustion delamination, on the contrary, yields damaged solar cells that are treated electrochemically or metallurgically to recover the metals. There is a need to critically investigate & manage the disposal and recycling of solar panels waste in a scientific manner to minimize the negative environmental impacts. This paper addresses handling and recycling of solar waste, which will be present in large quantities after 25 years and explain multiple adopted technologies to recycle solar waste and technological advancement achieved while recycling photovoltaic waste.

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Photovoltaic (PV) Modules Waste Management: A Holistic Framework For Sustainable Growth

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This paper is intended to study and develop a custom trained machine learning model which can detect potholes on road in real-time. Potholes and Road Craters are one of the key contributors of the numbers of accidents take place each year. A comparison for selection of object detection algorithm has been done in this paper. The proposed solution uses You Only Look Once (YOLO) version 7 object detection algorithm to train and be able to detect potholes and road craters. After training the model with the custom dataset, the model has achieved a precision of 0.94, recall value of 0.98. The mAP of the proposed solution 94.76%. The solution is able to detect potholes in both daylit and low-light real-time scenarios.

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Potholes, YOLO, CNN, Single Shot Detection, IoU, Detection, Craters, Road, Highway, Accident, Deep Learning

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Abstract Background Dengue virus single-stranded positive polarity ribonucleic acid RNA viruses of the family Flaviviridae are the most common cause of arboviral disease transmitted by the Aedes mosquito. We report a clinical epidemiological study of the dengue fever outbreak in 2022 from Noida hospitals in north India. Objective The study objective is to know the incidence of laboratory-confirmed cases among the suspected patients in the hospitals in Noida. Dengue is also observed in different ages. Material and method Was concerned with district hospital Gautam Buddha Nagar where 3,973 just have been conducted this year to check samples thank you of which 251 have been reported positive packet cases of dengue infection subjected to new capture enzyme-linked immunosorbent assay (ELISA) for detection of dengue virus-specific IgM antibody.1 Result Out of 3,973 tests have been reported positive dengue virus specific IgM antibodies year 2022 dengue cases as the study has been done in the month of July to December 2022.A slite spike has been seen this year as compared to the last 10 years. Conclusion It is a common health problem in India with stereo prevalence. The study examined in the present suggests that the effort of mobilized community members is essential for the sustainability of vector control methods and the generalizability of proven methods is recommended for the research.

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Dengue virus, ?-capture ELISA, Aedes mosquitoes, dengue, DF/DHF.

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Government, state, criminals, powers, police

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The most prevalent viral disease spread by arthropods is dengue fever . It causes sickness , high temperature, headache, arthralgia, myalgia, and rashes. In some critical situation, Dengue hemorrhagic fever (DHF) should also cause . The dengue shock syndrome would also been seen in this .

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Dengue fever , infection

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Abstract: Effective teachers are pursuing their efforts to enhance learning in terms of technology, reflected through the rapid progress of technology-based teaching and blended learning models. Education has become a reality in fulfilling the needs of present-day creative students. Blended learning is an educational program that combines online digital media with traditional classroom methods and educational devices with the physical presence of both teacher and student. An attempt is also made to study student teachers' perception of the Blended Learning Programme in terms of Survey type research. After the implementation of the Blended Learning Programme concerning the various dimensions, it is possible to increase the overall learner's academic performance. The study is also carried out to quantitatively analyze the Blended Learning Programme's effectiveness in improving student teachers' academic performance and pedagogical practices. Blended learning helps learners develop their various performances in the educational domain. Academic performance is the summation of different performance areas of learners to improve their abilities. The present paper intends to find out the relationship between learners' academic performance and their impact on blended learning for adolesc

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Stinging nettle (Urtica dioica) has a long history use as a medicinal herb found throughout the world that has used for medicinal purposes for centuries It has been used to treat asthma but synthetic drugs for the treatment of asthma and allergy in India found more side effects. Synthetic drugs used for the treatment of asthma and allergy in India but more side effects are reported. Over the centuries, they are using medicinal herbs in daily life and approximately 6000 plants species are known to have medicinal properties in India. As per the literature survey will be expressed medicinal plants and traditional systems of medicines, Ayurveda, Yunani, Siddha and Homeopathy for the treatment of asthma and allergy but no scientific validation. Several literatures are indicated that the herbal drugs have lesser adverse effects when compared to synthetic drugs. The Urtica dioica is not scientifically validated and which was traditionally using herb. The work provides scientific validation for use of leaves against asthma by revealing the chemical compounds may be present in the plant. The present study is attempts to develop a novel plant-based antihistamine work through anti asthmatic drug which will be evaluated by in vitro and in vivo.

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Mephramine ,anti-asthmatic activity; Stinging nettle leafs,

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Cluster-based Wireless Sensor Network information privacy is regarded as a difficult challenge for this sort of network. Because of the dynamic environment of WSNs and their deployment in open regions, they are subject to a variety of cyber-attacks that might disrupt their operations. Furthermore, due to the resource constraints of sensing devices, traditional security approaches in WSNs are impracticable due to the high cost of computing, communications, and memory capacity. The security in WSN has become a significant issue in the sensor network. The data which is transmitted from one node to another must be secured to avoid a data breach by any of the attackers. The link must be secured to ensure data efficiency and greater accuracy. This paper proposes the enhanced ECC algorithm for providing identity-based key encryption in cluster-based WSNs. A separate key generation concept has been proposed here to reduce the complexity of the network. The node-to-node has less number of key generations and the cluster head-to-sink node has a larger number of key generations. The results show that the proposed work holds good in minimizing the timing requirements for key generation, computation time is less, less energy consumption communication, and better packet-to-delivery ratio.

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WSN, Security, ECC, Cluster, Encryption Key

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ABSTRACT Aim: To assess the effectiveness of structured teaching programme on knowledge regarding human breast milk banking among antenatal mothers from selected hospitals, Pune. Objectives: a).To assess the knowledge regarding Human Breast Milk Banking among antenatal mothers from selected hospital before and after interventions. b). To find the association between the knowledge with selected demographic variables. Method: Pre-experimental non- randomized, one-group pre-test- post-test design, purposive sampling technique was used with sample size of 100 ANC mothers. Result: The mean pre-test score 5.7 increased to 6.8 in post-test of ANC mothers. Conclusion: It is evident that the knowledge among antenatal mothers regarding human breast milk banking improved significantly after structured teaching program.

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Key Words: - Knowledge, Antenatal Mothers, Human Milk Banking, Structured Teaching Programme

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In this venture, we are developing an internet wrongdoing detailing framework programme that can be accessed by people in the office as the number of detailed wrongdoing cases expands, but law enforcement discovers a gap between detailed wrongdoings and not-detailed violations. Numerous reasons may include this gap. It isn't a good thing to give hoodlums a chance to remain secure within the community as innocents, which prompts offenders to commit more violations. In India, the public was perplexed about the wrong grievances with respect to the office of government. With an online announcing framework, the public can report a wrongdoing without any fear, and they can effortlessly contact the office where they can unravel the issue in a viable way. This computer programme is safe because it can easily catch offenders by checking their past records from second-rate information and defensive for the client as well as for office and admin since there will be no spillage of any liberal of data. The online wrongdoing detailing foundation is an implementation that covers total case administration structure and this venture will offer assistance in overseeing all exercises of the police station it can utilized to report violations and oversee all the exercises in a police station utilizing computers.

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case management system, complaints, registration, safety tips, police station, automation

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Irony, comic, tragic, Bhasmasura myth, Valmiki myth, spiritual ascent, salvation

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Analysing the education system of any nation, from inception to present time, always requires meticulous reviewing of history- political frameworks since it has come to its present shape due to multitudinous influences from its past immemorial sources. Indian education system, right from its inception to present post-modern condition often evaluated as deeply sustained and modified product of multicultural traditions and legacies. Race, ethnicity, place conscious traditions, geographical implications, foreign invasions etc. all modified in the present articulated form of education practiced or rather revered in India. Education during Vedic junctures to dark medieval period to present Post-modern period appeared to be linked and structured by cultural strings of different educational legacies. Scotts and the Scottish missionaries in India had left a tremendous poignant mark in Indian education system. Their mission and erudite vision about education has transformed the educational setting and atmosphere looming large in India, engrossing socio-politico, intellectual and cultural spheres. The present study is, therefore, an attempt to elucidate their multi-faceted educational endeavours in the19th century India and the far-reaching consequences which continues to bedazzle and shape present Indian education system.

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Indian Education System, Vedic junctures, Traditions, Scottish missionaries, Cultural Spheres.

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Nokia SDM, SDL, Components of SDL

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The aim of this paper is to give an insight about the long run cointegration between second job holding, hours constraint (Hours of work in main job) and unemployment in North Macedonia. To establish the long run association, the Johansen Cointegration Analysis is applied on quarterly data obtained from Eurostat for the period of 2006 Q1 to 2020 Q4. Both the Trace and Maximum Eigenvalue tests confirm non-existence of any long run cointegration between second job holding, hours constraint and unemployment in North Macedonia.

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Second Job holding, Unemployment, Johansen Cointegration Analysis

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Modern implant therapy offers significant functional and biologic advantages for many patients when compared to conventional fixed or removable prostheses, and it also produces excellent long-term results, as evidenced by numerous 10-year studies with success and survival rates above 95%. As a result, it is a treatment modality that is frequently used in daily practice for fully and partially edentulous patients. Biomimetic agents, also known as biometric agents, are substances that may be implanted and copy or imitate certain bodily functions or structures (physiology). The specifications for implantable biometric agents Ability to promote the development of the proper cells to improve new bone production, reduced danger of infectious contagious disease transfer by simple synthesis or manufacture that avoids extraction from allografts, avoiding issues with implant loss owing to coating delamination by resorbability in response to osteogenic activity, chemical stability prior to implant insertion, no immune reaction generation. A bone-creating implant being tested in clinical settings by Nobel Biocare. The bone morphogenic protein rhBMP-2 (a recombinant form of a naturally occurring human protein) will be used to treat this implant, and the researchers assert that this treatment will fundamentally alter the indications for dental implants. Bovine bone filler demonstrated a low substitution rate and is widely used, not only for contour augmentation in early implant placement but also for internal augmentation. Bone fillers not only mechanically support barrier membranes to reduce risk of membrane collapse during healing, but they also have biologic properties, such as osteogenic potential to activate new bone formation, and a high or a low substitution rate, which will influence the stability of augmented bone. Implants are the latest trend to improve aesthetics and longevity of prosthesis.

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Dental implant, Biomimetic agents, Bone fillers, biometric agents

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Colonialism, environment, Amitav Ghosh, natives, anthropois

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Khayyam's personality was a very great one. He contributed Indian films much more in the field of music. The people of India and the world, forever, remember him.

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Classical Music

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