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ORAL THIN FILM : A STUDY OF APPLICABILITY AS A DRUG DELIVERY SYSTEM.
Authors
Parbhane M.B,Mourya Sudarshan Parshuram,Dr. Baheti Dwarkadas
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Keywords
oral thin films, hydrophilic polymer, nausea, vomiting
Abstract
The oral thin-film technology is still in the beginning stages and but most popular because it fulfils all the need of patients. In due course, these formulations having APIs will be commercially launched using the oral film technology. These can be prepared using hydrophilic polymers that rapidly dissolves on the tongue or buccal cavity, delivering the drug to the systemic circulation via dissolution when contact with liquid is made. Water-soluble polymers are used as film formers for fast dissolving films. It seems that the value on the whole oral thin film market will grow significantly.
The film has the ability to dissolve rapidly without the need for water provides an alternative to the patients receiving swallowing disorder patient suffering from nausea headache etc. Oral thin films (OTFs) are the most advanced and promising new approaches for drug delivery as it offers more flexibility and comfort. These enable an ease of administration, as there is no need to drink high amounts of liquids or swallow large solid dosage forms Also it improves the efficacy of APIs by dissolving within minute in oral cavity after the contact with less saliva as compared to fast dissolving tablets, without chewing and no need of water for administration. OTF offers an alternative to tablets, syrups or suppositories for treatment of vomiting and nausea, especially for the pediatric population.
IJCRT's Publication Details
Unique Identification Number - IJCRT2301189
Paper ID - 229806
Author type - Indian Author
Page Number(s) - b503-b521
Pubished in - Volume 11 | Issue 1 | January 2023
DOI (Digital Object Identifier) -
No Of Downloads - 147
Author Country - India, 412210, Shirur Pune, Shirur Pune, 412210, Pharmacy All
Publisher Name - IJPUBLICATION | www.ijcrt.org | ISSN : 2320-2882
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Parbhane M.B,Mourya Sudarshan Parshuram,Dr. Baheti Dwarkadas, "ORAL THIN FILM : A STUDY OF APPLICABILITY AS A DRUG DELIVERY SYSTEM.", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.11, Issue 1, pp.b503-b521, January 2023, Available at :http://www.ijcrt.org/papers/IJCRT2301189.pdf
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