Volume 9 | Issue 9

 Abstract

The main aim of the present work was to formulate fast dissolving oral film of Glycopyrrolate. Glycopyrrolate is an anticholinergic medication with a quaternary ammonium structure. It is a potent controller of Drooling observed in children affected with clebral plasy and has low oral bioavailability. This drug also undergoes first-pass metabolism. To overcome all these problems fast dissolving oral films were prepared which helps to improve the bioavailability of drugs. Oral films dissolve fastly along with drugs and mostly all drug absorbs through oral mucosa in the systemic circulation. Oral films were prepared by the solvent casting method. Pullulan and PEG 400 were optimized by using central composite 3 factor, 2 level design based on drug release, and thickness of films. A total of thirteen batches were prepared from which batch containing 50% Pullulan, 20% PEG was found to be best. Oral films of the optimized batch were disintegrated within 14 sec and show 85.60% drug release. The optimized film was further evaluated for drug content, folding endurance, pH values, disintegration time, percent elongation and physical appearance.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Poor saliva control, cerebral palsy, anticholinergic, drooling, glycopyrrolate, pediatrics, sialorrhea

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Sir Henry McMahon was an English Military Officer, with a distinguished service career in the British Armed Forces and several decorations for his valor on the battlefield. However, he was also an administrator for the British East India Company in the Region of India and the Middle East.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

International relations, Middle East, China

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Everything is not the same size all the time in life and our path is so crooked. We have to cross the ups and downs of that life and we get obstacles at every step. Just like Anamika has become our representative in real life, it is not that we will realize all the good things in every moment of life but not the bad ones. In fact, the author Kana Basu Mishra has given the example that there is one Anamika in every human being. Anamika is therefore not just a character in the novel, Anamika is the burning representative of our lives. He is surrounded by the people of the society, the people of his house and his surroundings and above all his own position- which puts us in front of a big question mark. Just like the Chakkar novel helps us to raise the question, Anamika throws us, who are we and why?

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Society, New life, External and Internal world, Survival, Survive, Struggles

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Abies pindrow, Aloe barbadensis (Aloe vera), Bixa orellana and Hibiscus rosa.

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Manifold development in science and technology is the contemporary world with competitiveness. The educational system has been affected drastically by this and there is an enormous expansion and growth everywhere. Academic Achievement is an integral part of the students life that decides his professional desires and is a due for the student to gain an understanding of his talents and potentialities. to beat this competition achieving good score is an imperative factor, that labels a student as successful or unsuccessful. In the present study, the researcher difference levels of anxiety. The researcher has made an attempt to find out the different levels of anxiety and thus determine the correlation between anxiety and academic achievement. Attempts have been made by the researcher to explore the gender specific disparity in relation to academic achievement. A sample of 100 student (50 boys, 50 girls) of senior secondary school class XIth were selected randomly from two schools of Lucknow city. Keywords :- Academic Achievement, Anxiety,

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Academic Achievement,Anxiety

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

India and China are the two biggest nations in the world and constitute largest economy and military power in Asia as well as in the globe. Both the countries have developed their diplomatic relations since their formation as political entities. They have concluded many agreements and summits for the promotion of bilateral relations in trade and security arrangements. The trade relation between them has been climbed to some height from its commencement but security aspect was lacked behind too much beyond the expectation. Both the countries have differences and confrontations on many grounds and issues, and are playing proxy war against each other on different platforms. Border conflict continues to poison the bilateral relations. USA has withdrawn from the security arrangement of Afghanistan and Taliban has captured the political system of the said country in their barren hands. The regime change in the Eurasian land mass has brought both opportunities and challenges for the world powers especially for India and China. The Central Asians are mostly Muslim majority countries and share borders with China and Afghanistan directly and with India and Pakistan as extended neighbours. The Kashmir state in India having Muslim majority populations are very prone for the outfit groups to play their cards. In that context the geographical proximity of the Central Asia with terrorist affected countries like Afghanistan and Pakistan have security implications for themselves as well as for India also which are already suffering from terrorism and extremism. China can use the outfit groups with the help of Pakistan against India to play its hidden agenda or to circle India by its geo-strategic arrangement in the region. This paper will not only try to find out a scope for cooperation between India and china in security arrangement in central Asia but also will search for areas of same interests to bring them together on multiforums in South Asia.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Terror-politics nexus, hidden agenda, raw materials, outfit groups, security arrangement, Confrontation and Cooperation.

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

- Discovery, Facts, Investigation, Malaria, Vector.

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Superabsorbent polymer is a polymer of hydrophilic networks that effectively absorb & retain large amount of aqueous solutions. Superabsorbent polymers are widely employed for various applications such as in sanitary products, agricultural and horticultural activities. Superabsorbent polymers are classified into two types natural and synthetic. Natural super absorbents are polypeptide and polysaccharide based whereas synthetic super absorbents are petrochemical based. The type of biomass, dosage of initiator, crosslinker and other factors responsible in changing the absorption capacity of the material are studied. A fertilizer stick was made using the superabsorbent polymer and slow release fertilizers. Trials & biodegradability studies were carried out. The study revealed that the paddy straw- SAP composite can absorb 208g/g of water and it was greatly affected by ph. Paddy straw-graphite oxide SAP composite had an absorption capacity of 326g/g in distilled water. The fertilizer stick was effective in supplying the slow release micronutrient to the plants.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Superabsorbent polymer, fertilizer, agriculture, slow release, graphite oxide

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

The study was conducted to compare the attitude of secondary school students, teachers and community members towards sex education. Stratified random sampling method was adopted by selecting 400 secondary school students, teachers and community members respectively. Attitude Scale towards sex education developed and standardized by the researchers was used for collection of data. Analyses were done by testing the hypotheses to find out the significant difference in which it was found that there was no significant difference between the attitude of the students and community members. But significant difference was found between the attitude of students and teachers and teachers and community members.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Sex education, attitude, secondary school students, teachers, community

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

In the present study, GIS maps are used to investigate the water sources in Arang Block. The study was carried out to assess the surface and groundwater quality of the (Arang Block) Raipur District, Chhattisgarh. The study area is located between latitude 21.195 and longitude 81.967. Water quality is one of the most important concerns. The heavy metals up to ppm. levels in drinking water quality may because genuine health Complication and also cause cancer. In this study we make a venture to know the concentration of Four heavy metals in ground water and surface water in different places of (Arang Block). For this study, water tests were collected in pre-monsoon May-Jun. These tests were subjected to analysis for four elements like Ca, Cr, Fe, and Pb by using UV-VIS-NIR. A spectrophotometer is the most modern technique for the determination of find metal concentration. The concentration of these metals was differentiated with drinking water quality limits given by the World Health Organization (WHO) 4th edition in 2011.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Groundwater, Surface water, GIS Mapping (Pre-Monsoon), UV-VIS- NIR Spectrophotometer, WHO, Arang Block, Raipur District.

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Mechanical engineering, Automobile engineering, Design Engineering

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

In the People's Republic of China, religion has long been a contentious issue. Because the present Chinese image of religion is founded on a strongly secularist framework, religion has historically occupied a small portion of society, particularly in the educational arena. Although religion was permitted to some extent during the Republic's early years due to many other pressing concerns, all religious traditions were mercilessly destroyed in the late 1950s, particularly during the Cultural Revolution (1966-1976). Following the Cultural Revolution, particularly during the 1980s, the government began to treat all religious perspectives and religions with more tolerance and acceptance due to newly-launched reform and opening-up programs (simplified Chinese). As a result, a diverse spectrum of traditional traditions, beliefs, and faiths was allowed to resurge and flourish to some extent. Authorities began to see a link between religious convictions and state security in the late 1990s, particularly in Falun Gong and Islam. The government's vocabulary has become progressively comparable to that of the west, where "war on terror" movements have targeted Muslims and their faith (Hilal, 2017).

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

THE ORIGIN AND DEVELOPMENT OF ISLAM IN CHINA

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Image enhancement is a common method of improving the look and feel of a photograph. This idea for underwater picture enhancement was inspired by the shape and function of a teleost fish retina. The blurring and non-uniform colour biases in underwater photos are causing problems. Using red channel compensation and feedback from color-sensitive horizontal cells helps to correct the eye's unbalanced perception of colours. To improve the output image's edges and contrasts, the bipolar cell has a center-surround opponent mechanism and feedback from amacrine cells to inter-plexiform cells. It is possible to use the color-opponent ganglion cells to enhance and correct colour. Finally, we're using a fusion technique based on brightness to reconstruct the improved image from fish retina outputs that are both on and off. To construct each low-level filter automatically, our approach employs global data (such as picture contrast), which allows the major parameters to self-adapt. Extensive qualitative and quantitative examinations of our technology in diverse underwater settings demonstrate its competitive performance. Our technique also improves the transmission map estimate and local feature point matching accuracy when using an underwater image. Our methodology is based on a single image and does not require any prior knowledge of the undersea scene's condition or structure. For greater colour contrast and colour correction, used technique is Laplacian multiscale fusion reconstruction method. Results and parameter computations will reveal the disparity between the proposed work and actual performance data.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Fish Retinal Mechanism, Laplacian Multi-scale fusion Reconstruction, Dehazing, UnderWater Image Processing.

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Schizophrenia stands for a long-lasting state of mental uncertainty that may bring to an end the relation among behavior, thought, and emotion; that is, it may lead to unreliable perception, not suitable actions and feelings, and a sense of mental fragmentation. Indeed, its diagnosis is done over a large period of time; continues signs of the disturbance persist for at least 6 (six) months. Once detected, the psychiatrist diagnosis is made through the clinical interview and a series of psychic tests, addressed mainly to avoid the diagnosis of other mental states or diseases. Undeniably, the main problem with identifying schizophrenia is the difficulty to distinguish its symptoms from those associated to different untidiness or roles. Therefore, this work will focus on the development of a diagnostic support system, in terms of its knowledge representation and reasoning procedures, based on a blended of Logic Programming and Artificial Neural Networks approaches to computing, taking advantage of a novel approach to knowledge representation and reasoning, which aims to solve the problems associated in the handling (i.e., to stand for and reason) of defective information.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Schizophrenia, brain disorder, Neural Networks, Identification, Symptoms.

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

COVID-19, Engagement in meaningful activities, Internet Addiction, Internet Consumption, Meaningful Occupations

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Evolution of an existing drug molecule from a conventional form to a novel delivery system can significantly improve its performance in terms of patient compliance, safety and efficacy. In the form of a Novel Drug Delivery System an existing drug molecule can get a new life. An appropriately designed Novel Drug Delivery System can be a major advance for solving the problems related towards the release of the drug at specific site with specific rate. The need for delivering drugs to patients efficiently and with fewer side effects has prompted pharmaceutical companies to engage in the development of new drug delivery system. This article covers the basic information regarding Novel Drug Delivery Systems and also different types of the same.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Nanomedicine, natural plant metabolite, biomedical application, carrier formulation, drug delivery

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Groundwater, Surface water, GIS Mapping (Pre-Monsoon), UV-VIS-NIR Spectrophotometer, WHO, Abhanpur Block, Raipur District

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Composite material is a material made from two or more constituent materials or Viscoelastic Damping Materials (VDM) with significantly different physical or chemical properties. These materials when combined; produce a material with characteristics different from the individual components. Viscoelastic Damping Materials (VDM) have behaviour which falls between elastic and viscous extremes, therefore some of the energy is recovered upon removal of the load, and some is lost or dissipated in the form of thermal energy. The phenomenon of VEM opens a new horizon for researchers with a tremendous scope to design and investigate a new composite material especially for shock absorbing and vibration damping applications. The use of composites have become more and more important in engineering applications because of their low cost, light weight, high specific strength and good corrosion resistance. This research work aims to evaluate the response of composite material in order to enhance its use for the intended function. The work shall focus on identifying significant control parameters for vibrational characteristics and the effect of altering these parameters. The performance of the composite material in the context of vibration analysis shall be evaluated for offering recommendation of a set of levels for the configuration under study.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Composite Material, VDM, FFT Analyzer, Damping, Variation in Thickness.

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Cloud computing is the development of parallel computing, distributed computing, grid computing and virtualization technologies which define the shape of a new era. Cloud computing is an emerging model of business computing. In this paper, we explore the concept of cloud architecture and compares cloud computing with grid computing. We also address the characteristics and applications of several popular cloud computing science. We introduce to the issues of cloud computing. We identified several challenges from the cloud computing adoption perspectives and we also highlighted the cloud interoperability issues that deserve substantial further research and development. However, security and privacy issues present a strong barrier for users to adapt into cloud computing systems.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

- Cloud computing, architecture, challenges, cloud platforms, research issues

  License

Creative Commons Attribution 4.0 and The Open Definition