Volume 10 | Issue 8

 Abstract

Licence: creative commons attribution 4.0

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Rabha, Totola Rabha, marriage, customs, tradition.

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

This study was aimed at the synthesis of fused Phenothiazine derivatives containing heterocyclic moiety. The synthesized compounds were tested for their preliminary tests, physical constants, TLC, IR, 1H-NMR Spectra and CHN analysis confirmed the structures of the final compounds. Antidepressant activity of all the synthesized compounds was evaluated by despair swim test by using Sprague Dawley Rats. Standard drug Imipramine was used as the control. In the despair swim test, all the synthesized derivatives showed antidepressant activity. Among them three Compounds (A7, A8, and A10) showed significant antidepressant activity comparing with control drug imipramine. These results are useful for the further investigation in the future.

Licence: creative commons attribution 4.0

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Antidepressant activities, Despair swim test, Phenothiazine and Sprague Dawley Rats.

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Background: Globally, work place safety does not occur without a challenge especially in resource constrained set up. In Ethiopia, patient safety culture is a relatively new focus, and little is known regarding the current status of patient safety in public hospitals. This is further worsened by poor hazard control system, lack of task management system and role ambiguity. Aim: This study mainly tried to measure work place of health and safety about administrative staffs and admitted patients in St. Paul`s hospital Millennium Medical College, Addis Ababa, Ethiopia. The compliance to occupational health and safety measures among workers and patients from study site. Methodology: This Study took for considering exploratory and conclusive based descriptive cross-sectional design involving quantitative data collection approaches. It was carried out among administrative staffs and admitted patients at St. Paul`s Hospital Millennium Medical College, Addis Ababa, between 1st May 2019 and 7th July 2019. From a study population of 318 administrative staffs and 180 admitted patients, about 70 participants were selected by simple random sampling lottery methods, structured non-discussed questionnaire. It is close ended directive questions. Data analysis involved descriptive and inferential statistics. Differences in the parameter of estimate were considered significantly different at P<0.05. Results: Study findings showed that four factors were significantly associated with health and safety regulations to measure safety with P<0.05, these includes; factors associated with health and safety status of administrative staffs, factors associated with health and safety regulator of administrative staffs, factors associated with hospital accident incidence of administrative staffs, and factors associated with hospital environmental factors of patients. Conclusion: Finally, Most of the workers were satisfied with the health and safety measures adopted in the hospital. This implies that the role of management in implementing health and safety in the organization is very effective. But there was reveals evidence of poor awareness of the administrative staff workers and admitted patients about health and safety in the workplace is inadequate. Also repeated accidents like fallen from height, Hepatitis, TB/MDR (multi drug resistance), and hospital acquired infection are occurred in the work place. Therefore suitable ideas were suggested to the health facility administrators to avoid those accidents and to improve the health and safety measures. If the hospital implements effective disciplinary procedures; it will help the hospital to go with their policies and also to maintain health and safety in the organization.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Health measures, safety measures, Health facility; Health policy, Employee safety, Patient safety.

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Creative Commons Attribution 4.0 and The Open Definition