ISSN Approved Journal No: 2320-2882 | Impact factor: 7.97 | ESTD Year: 2013
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 7.97 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
IJCRT Journal front page | IJCRT Journal Back Page |
Paper Title: GENERALIZED HOMOMORPHISM AND ANTI HOMOMORPHISM OF FUZZY IDEAL OF A RING
Publisher Journal Name: IJCRT
Published Paper ID: - IJCRT2108243
Register Paper ID - 210914
Title: GENERALIZED HOMOMORPHISM AND ANTI HOMOMORPHISM OF FUZZY IDEAL OF A RING
Author Name(s): B.AMRINTAJ, V.PRIYADHARSHINI, V.ANGESHWARI, S.PRIYANKA
Publisher Journal name: IJCRT
Volume: 9
Issue: 8
Pages: c278-c289
Year: August 2021
Downloads: 833
In this paper we discussed about the multi fuzzy set and multi dimensional membership, fuzzy multi ideal , fuzzy multi ring and apply to the theory of ring and in their notations.
Licence: creative commons attribution 4.0
Paper Title: KEY WORDS : VIRTUAL TEACHING, ONLINE EDUCATION, PERILS OF MOBILE LEARNING, DIGITAL TOXIN
Publisher Journal Name: IJCRT
Published Paper ID: - IJCRT2108242
Register Paper ID - 211035
Title: KEY WORDS : VIRTUAL TEACHING, ONLINE EDUCATION, PERILS OF MOBILE LEARNING, DIGITAL TOXIN
Author Name(s): DR.A J A RANJTSINGH, P.DHASARATHAN
Publisher Journal name: IJCRT
Volume: 9
Issue: 8
Pages: c261-c277
Year: August 2021
Downloads: 762
The prevailing pandemic situation has imposed social isolation to prevent the spread has yielded positive results globally. In India also serious attention is focused by the Central and State governments and all educational institutes are closed for more than an academic year. To continue the education system instead of face to face pedagogical system virtual mode of education was promoted. For the online or virtual mode of teaching and learning digital gadgets particularly mobile phones are maximum used. The school going children from the of KG to 10+2 class are using the online mode of class conduction. The small i-kids in the tender age are also compelled to listen the classes through mobile for hours together. But there are several complications behind the use of mobile phones for long hours. The radiations from the digital gadgets were proved to cause digital toxin to human system,. Besides a lot of pschyco-social environmental aberrations are caused among the children due to this mode of learning. To save the Indian children the future of our Nation from possible health and social hazards in the years to come some alternative teaching technology must be developed. With this central dogma the proposed study, a blend of review and personal data collection emphasizes the imperative need for a change in the online mode of education to school children. Key words : Virtual teaching, online education, perils of mobile learning, digital toxin The prevailing pandemic situation has imposed social isolation to prevent the spread has yielded positive results globally. In India also serious attention is focused by the Central and State governments and all educational institutes are closed for more than an academic year. To continue the education system instead of face to face pedagogical system virtual mode of education was promoted. For the online or virtual mode of teaching and learning digital gadgets particularly mobile phones are maximum used. The school going children from the of KG to 10+2 class are using the online mode of class conduction. The small i-kids in the tender age are also compelled to listen the classes through mobile for hours together. But there are several complications behind the use of mobile phones for long hours. The radiations from the digital gadgets were proved to cause digital toxin to human system,. Besides a lot of pschyco-social environmental aberrations are caused among the children due to this mode of learning. To save the Indian children the future of our Nation from possible health and social hazards in the years to come some alternative teaching technology must be developed. With this central dogma the proposed study, a blend of review and personal data collection emphasizes the imperative need for a change in the online mode of education to school children.
Licence: creative commons attribution 4.0
Key words : Virtual teaching, online education, perils of mobile learning, digital toxin
Paper Title: ASSESSMENT OF NUTRITIONAL STATUS OF CRITICALLY ILL PATIENTS TILL DISCHARGE FROM HOSPITAL.
Publisher Journal Name: IJCRT
Published Paper ID: - IJCRT2108241
Register Paper ID - 211054
Title: ASSESSMENT OF NUTRITIONAL STATUS OF CRITICALLY ILL PATIENTS TILL DISCHARGE FROM HOSPITAL.
Author Name(s): Ms.Athira Chandran, Dr.Padmaja Dhawale
Publisher Journal name: IJCRT
Volume: 9
Issue: 8
Pages: c232-c260
Year: August 2021
Downloads: 769
Aim of the study is to assess and compare the nutritional status of critically ill patients till discharge from hospital and to find the association between type of feed and length of ICU stay with nutritional status of critically ill patients. Descriptive evaluatory approach with quasi experimental exploratory descriptive design was adopted. Observational checklist to assess the nutritional history and modified Subjective Global Assessment for body composition to assess the nutritional status of critically ill patients were used. On admission demographic data, medical history and a basis nutritional history and nutritional assessment were done. On every third day till discharge nutritional history and nutritional assessment were performed.
Licence: creative commons attribution 4.0
Assessment, Nutritional status, critically ill patients, Subjective Global Assessment guidance for body composition
Paper Title: INTERNATIONAL FINANCIAL REPORTING STANDARDS (IFRS) IN INDIA: PROBLEMS AND CHALLENGES
Publisher Journal Name: IJCRT
Published Paper ID: - IJCRT2108240
Register Paper ID - 210940
Title: INTERNATIONAL FINANCIAL REPORTING STANDARDS (IFRS) IN INDIA: PROBLEMS AND CHALLENGES
Author Name(s): Lakshmi Sree P
Publisher Journal name: IJCRT
Volume: 9
Issue: 8
Pages: c224-c231
Year: August 2021
Downloads: 804
Globalization has laid down a way for all the countries to adopt a single set of accounting standards. Recent years have seen major changes in financial reporting worldwide under which the most obvious is the continuing adoption of IFRS worldwide. More than 100 countries have converged or recognized the police of convergence with the IFRS. IFRS are the globally accepted accounting standards and interpretations adopted by the IASB. An upcoming economy on world economic map, India, too, decided to converge to International Financial Reporting Standards (IFRS). In India, ICAI has decided to adopt the IFRS by April 2011. This paper discusses the IFRS adoption procedure in India and the utility for India in adopting IFRS, the problems and challenges faced by the stakeholders and its impact on India. Lastly, paper concludes with the ways through which these problems can be addressed.
Licence: creative commons attribution 4.0
Globalization, Financial reporting, Problems, Challenges.
Paper Title: HPTLC METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF ELLAGIC ACID, GLYCYRRHIZIC ACID AND KAEMPFEROL IN HERBAL FORMULATION
Publisher Journal Name: IJCRT
Published Paper ID: - IJCRT2108239
Register Paper ID - 211039
Title: HPTLC METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF ELLAGIC ACID, GLYCYRRHIZIC ACID AND KAEMPFEROL IN HERBAL FORMULATION
Author Name(s): Ms. Dipali Dilip Suryawanshi, Dr. Mrs. Varsha Milind Jadhav, Dr. Vilasrao J. Kadam
Publisher Journal name: IJCRT
Volume: 9
Issue: 8
Pages: c204-c223
Year: August 2021
Downloads: 795
Licence: creative commons attribution 4.0
Ellagic acid, Glycyrrhizic acid, Kaempferol, Herbal formulation, Estimation, HPTLC, Standardization, Method development and validation.
Paper Title: A STUDY OF TRIBAL EDUCATION IN INDIA: CHALLENGES AND OPPORTUNITIES IN COVID-19 PANDEMIC PERIOD
Publisher Journal Name: IJCRT
Published Paper ID: - IJCRT2108238
Register Paper ID - 211019
Title: A STUDY OF TRIBAL EDUCATION IN INDIA: CHALLENGES AND OPPORTUNITIES IN COVID-19 PANDEMIC PERIOD
Author Name(s): Manoj Kumar Sadual, Girish Ranjan Sahoo
Publisher Journal name: IJCRT
Volume: 9
Issue: 8
Pages: c195-c203
Year: August 2021
Downloads: 826
Education is a whole person development designed to inculcate knowledge, skills and attitudes necessary to empower individuals to cope efficiently with their environment. However, in a highly competitive world the quality of performance has become the basic factor for personal and social progress and it is generally measured by achievement. The current study was carried out among tribals. In the current COVID-19 pandemic period is a major barrier to the education of the tribes. The purpose of this study is to bring Tribal educators back into the mainstream of education in COVID-19 pandemic period and improve their quality of life. The researcher finds that the education of ST boys and girls basically affected for a long time in COVID-19 situation. Researcher analyzes their own perspectives and judgments from the data and identify educational barriers and with several suggestions to overcome this barriers. This study helps in the COVID-19 Pandemic period and its outcome understand the educational barriers and remove the educational barriers for different Tribes, in India.
Licence: creative commons attribution 4.0
COVID-19 Pandemic Period, Tribal educators, Educational barriers
Paper Title: EFFECT OF EDTA ON SEED GERMINATION AND SEEDLING GROWTH OF HORDEUM VULGARE L.
Publisher Journal Name: IJCRT
Published Paper ID: - IJCRT2108236
Register Paper ID - 211014
Title: EFFECT OF EDTA ON SEED GERMINATION AND SEEDLING GROWTH OF HORDEUM VULGARE L.
Author Name(s): Dr. Preeti Singh
Publisher Journal name: IJCRT
Volume: 9
Issue: 8
Pages: c185-c189
Year: August 2021
Downloads: 818
The present work was carried out to study the effect of EDTA on the seed germination and seedling growth of Hordeum vulgare. Seeds of barley were treated with different concentrations of EDTA (40, 80,120 and 160 mmol/l). The seed germination was recorded maximum for control, while the germination percentage decreased with the increasing concentrations of EDTA. Delayed seed germination and cytotoxic effects on cell divisions were also observed in the treated sets. The study showed that the survival and growth of the seedlings were negatively affected by the elevated EDTA concentration.
Licence: creative commons attribution 4.0
Hordeum vulgare, EDTA, Coleoptile, Mitotic index
Paper Title: Music: A grand combination of sound and Rhythm
Publisher Journal Name: IJCRT
Published Paper ID: - IJCRT2108235
Register Paper ID - 211032
Title: MUSIC: A GRAND COMBINATION OF SOUND AND RHYTHM
Author Name(s): Dr. Arti Sisodia
Publisher Journal name: IJCRT
Volume: 9
Issue: 8
Pages: c183-c184
Year: August 2021
Downloads: 774
Music: A grand combination of sound and Rhythm
Licence: creative commons attribution 4.0
Music: A grand combination of sound and Rhythm
Paper Title: VERMICOMPOSTING A STEP TOWARDS ORGANIC FARMING
Publisher Journal Name: IJCRT
Published Paper ID: - IJCRT2108234
Register Paper ID - 211047
Title: VERMICOMPOSTING A STEP TOWARDS ORGANIC FARMING
Author Name(s): Gavane Pramod Bhanudasrao, Gavhane Sachin Sharad
Publisher Journal name: IJCRT
Volume: 9
Issue: 8
Pages: c179-c182
Year: August 2021
Downloads: 780
The Green Revolution in the year 1960 changed the whole scenario in the field of agriculture where the farmers were introduced to high yielding seeds and fertilizers to maintain food security. Increasing productivity ensured profit but ultimately the land was turning barren due to the excessive usage of fertilizers making the soil infertile and pesticides turning the product dangerous to consume.so instead of using fertilizers ,farmers can use vermicompost due to which food production will increases but also people will get organic food.
Licence: creative commons attribution 4.0
Vermicomposting,Organic farming
Paper Title: A STUDY AND ANALYSIS OF SELECT CHARACTERS IN PARO ANAND`S `LIKE SMOKE`
Publisher Journal Name: IJCRT
Published Paper ID: - IJCRT2108233
Register Paper ID - 210864
Title: A STUDY AND ANALYSIS OF SELECT CHARACTERS IN PARO ANAND`S `LIKE SMOKE`
Author Name(s): Suman Kushwaha, Dr. Prarthana Vardhan
Publisher Journal name: IJCRT
Volume: 9
Issue: 8
Pages: c171-c178
Year: August 2021
Downloads: 804
Licence: creative commons attribution 4.0
Humiliation, torture, aggression, embarrassment, primary agents, stakeholders
Paper Title: AN ANTIOXIDANT PROPERTIES OF KALMEGH (ANDROGRAPHIS PANICULATA)
Publisher Journal Name: IJCRT
Published Paper ID: - IJCRT2108232
Register Paper ID - 210866
Title: AN ANTIOXIDANT PROPERTIES OF KALMEGH (ANDROGRAPHIS PANICULATA)
Author Name(s): Dr. Kavita Patel, Kusum Lata Khunte
Publisher Journal name: IJCRT
Volume: 9
Issue: 8
Pages: c163-c170
Year: August 2021
Downloads: 833
A large portion of the restorative plants have been utilized for therapeutic purposes before ancient period. Among antiquated human advancements India known as rich vault of therapeutic plants. In this paper we examine about cancer prevention agent property of the significant restorative plant Kalmegh. Cancer prevention agent property of this plant is more valuable in person. The status of defensive component against oxidants, the cell reinforcements in human mirror the dynamic harmony between cancer prevention agent protection and peroxidant conditions and have been proposed as a valuable apparatus in assessing the danger of oxidative harm. The point of the current exploration is cell reinforcement movement of leaf separate, stem concentrate and organic product extricate in Kalmegh ( Andrographis paniculata ). We discover A. paniculata, natural product extricate shows 87 % higher searching potential than the leaf remove 86 % and stem separate 80.48 % With the ascent in conc. of A. paniculata absorbance diminishes and % restraint rises.
Licence: creative commons attribution 4.0
Antioxidant , , Andrographolide , Diterpenoids , DPPH , Flavonoids ,TRIS buffer
Paper Title: ENERGY-EFFICIENT ROUTING PROTOCOL FOR WIRELESS SENSOR NETWORK: A COMPARATIVE STUDY
Publisher Journal Name: IJCRT
Published Paper ID: - IJCRT2108231
Register Paper ID - 210541
Title: ENERGY-EFFICIENT ROUTING PROTOCOL FOR WIRELESS SENSOR NETWORK: A COMPARATIVE STUDY
Author Name(s): Kanak tripathi, Sudhir agarwal
Publisher Journal name: IJCRT
Volume: 9
Issue: 8
Pages: c152-c162
Year: August 2021
Downloads: 891
The modern and present-day developments are more focused on transmitting delicate information to the final destination. To fulfil this criterion, sensor nodes (SN) have been developed, which integrate various sensing and computing unit along with the power supply, the transceiver in one single unit. These sensor nodes combined to form a network called wireless sensor networks (WSNs). WSN have a vast application like industrial monitoring, forest fire detection, border protection and security, water quality monitoring and so on. The pre-existing research mainly focused on reducing energy consumption during the process of computing and transferring data to BS. Sensors in the various applications of WSNs establish remotely in large numbers and operate autonomously. Although clustering is an effective way to increase network lifetime by using energy efficiently. Unequal or heterogeneous clustering is used in which the size of the cluster varies according to the distance of BS. Keeping all these issues, in this paper we have classified various routing protocols for WSN with their methods, advantages and disadvantages which is helpful for the next generation of WSNs.
Licence: creative commons attribution 4.0
Keywords: Wireless sensor network; Cluster head; Clustering algorithms; network architecture; lifetime.
Paper Title: EFFECT OF FDM PROCESS PARAMETERS ON TENSILE STRENGTH OF PLA
Publisher Journal Name: IJCRT
Published Paper ID: - IJCRT2108230
Register Paper ID - 210985
Title: EFFECT OF FDM PROCESS PARAMETERS ON TENSILE STRENGTH OF PLA
Author Name(s): M Rupesh, Dr. Ravindra Kommineni
Publisher Journal name: IJCRT
Volume: 9
Issue: 8
Pages: c147-c151
Year: August 2021
Downloads: 866
In rapid prototyping (RP), 3D printing is growing fast due to its ability to build different complex geometrical shapes and structures in the least possible time. In this manufacturing process, a computer-aided design (CAD) model is used to fabricate a physical model. The prototype is made by deposition of material in layer by layer. The major advantage of this manufacturing process is that it can fabricate complex parts quickly with minimum loss of material. There are many rapid prototyping techniques available commercially. Fused deposition modeling (FDM) is one of the most widely used methods. The mechanical behavior of 3D printed fabricated PLA parts depends on the interaction of different process parameters and the raw material properties. In this work, the effect of process parameters, namely layer thickness, Volume Infill, and print speed, has been studied on mechanical properties like tensile strength. It was observed that tensile strength increased with an increase of volume infill, minimizing print speed and layer thickness. The experimental results are compared with the simulated results from ANSYS.
Licence: creative commons attribution 4.0
PLA, FDM, Tensile Strength, ASTM D638-14, FEA.
Paper Title: TECHNOLOGY BASED EDUCATION SYSTEM IN NEW NORMAL WORLD EFFECTS THE STUDY OF THE PASTORAL STUDENTS
Publisher Journal Name: IJCRT
Published Paper ID: - IJCRT2108229
Register Paper ID - 210986
Title: TECHNOLOGY BASED EDUCATION SYSTEM IN NEW NORMAL WORLD EFFECTS THE STUDY OF THE PASTORAL STUDENTS
Author Name(s): Prithaprana Swarnakar, Dr. Swadesh Ranjan Samanta
Publisher Journal name: IJCRT
Volume: 9
Issue: 8
Pages: c145-c146
Year: August 2021
Downloads: 774
Licence: creative commons attribution 4.0
Technology based Education System in New Normal World Effects the Study of the Pastoral Students
Paper Title: A STUDY TO ASSESS THE ATTITUDE REGARDING CARE OF CHILD WITH AUTISM AMONG THEIR PARENTS IN A SELECTED HEALTH CARE SETTING AT BANGALORE
Publisher Journal Name: IJCRT
Published Paper ID: - IJCRT2108228
Register Paper ID - 210988
Title: A STUDY TO ASSESS THE ATTITUDE REGARDING CARE OF CHILD WITH AUTISM AMONG THEIR PARENTS IN A SELECTED HEALTH CARE SETTING AT BANGALORE
Author Name(s): Mangayarkarasi D
Publisher Journal name: IJCRT
Volume: 9
Issue: 8
Pages: c135-c144
Year: August 2021
Downloads: 780
Autism is a developmental and behavioural pattern, the triad of impairments of social interaction, social communication and imagination. The objective of the study was to assess the attitude regarding care of child with autism among the parents in a selected health care setting at Bangalore. The study was conducted to impart favourable attitude among parents of autistic child on care of child with autism. A quantitative approach with Non experimental descriptive survey design was used for the study. Hundred samples were selected by non-probability convenience sampling technique. The study instrument used was as follows: demographic data and Likert scale to measure the attitude. The tools were administered after obtaining the administrative and informed consent. The collected data were analysed using descriptive and inferential statistics with the help of SPSS version 20.0. It was inferred that regarding attitude maximum number of the parents 48 (48%) had neutral attitude, 31 (31%) of parents had favourable attitude and 21 (21%) of parents had unfavourable attitude.
Licence: creative commons attribution 4.0
Assess, Attitude, Child, Autism, Parents
Paper Title: DIVERSITY OF FAMILY CONVOLVULACEAE IN AMBEGAON TEHASIL DISTRICT PUNE (M.S) INDIA
Publisher Journal Name: IJCRT
Published Paper ID: - IJCRT2108227
Register Paper ID - 210992
Title: DIVERSITY OF FAMILY CONVOLVULACEAE IN AMBEGAON TEHASIL DISTRICT PUNE (M.S) INDIA
Author Name(s): Kumawat.V.S., Shaikh.S.G.
Publisher Journal name: IJCRT
Volume: 9
Issue: 8
Pages: c125-c134
Year: August 2021
Downloads: 815
One of the most important task is to prepare cheacklist of plants all over the world.The family Convolvulaceae which is also known Morning glory or Bindweed family because of flowers mostly open during morning time only.In this family there are total 57 genera and about more thant 1650 species are found all over the world. Out of them 20 Genera and about 177 Species are found in India.The largest genus is Ipomoea having 600 species , Jacqumontia 115 and Evolvulus 98 Species. This paper is based on diversity of pof family Convolvulaceae in the tehasil Ambegaon Dist. Pune (M.S) India. We have recorded 8 genera and 21 Species. In this dominant genera is Ipomoea having 10 species which is followed by Merremia having 4 species.The rare genera are Rivia and Jacquemontia having only one species. Family Convolvulaceae is economically important as Food , Medicine and Ornamentals.
Licence: creative commons attribution 4.0
Diversity , Convolvulaceae, Ambegaon ,Pune
Paper Title: A STUDY ON TOPOLOGICAL CHARACTERIZATIONS OF LINEARITY
Publisher Journal Name: IJCRT
Published Paper ID: - IJCRT2108226
Register Paper ID - 210915
Title: A STUDY ON TOPOLOGICAL CHARACTERIZATIONS OF LINEARITY
Author Name(s): P.PRIYANKA, M.RAJARAJESWARI, P.THIRUSELVI, C.GLORIREENA
Publisher Journal name: IJCRT
Volume: 9
Issue: 8
Pages: c106-c124
Year: August 2021
Downloads: 806
The space having uniformities with a totally ordered base are characterized in bigger classes of non-archimedean space and suboderable space, consequntey serveral new matrization results are obtained by exampie,we show that the condition used in our main theorem cannot be weakened essentially.our example may be interesting else where. In this paper we shall give the most important topological porperties of semi-linear uniform space( )
Licence: creative commons attribution 4.0
semi liner uniform space, topological properties
Paper Title: REVIEW PAPER ON INTERNET OF THINGS BASED ENERGY METER WITH LOAD PARAMETER ANALYSIS
Publisher Journal Name: IJCRT
Published Paper ID: - IJCRT2108225
Register Paper ID - 210882
Title: REVIEW PAPER ON INTERNET OF THINGS BASED ENERGY METER WITH LOAD PARAMETER ANALYSIS
Author Name(s): Vaishali Lokhande
Publisher Journal name: IJCRT
Volume: 9
Issue: 8
Pages: c101-c105
Year: August 2021
Downloads: 816
Licence: creative commons attribution 4.0
Internet of Things , Microcontroller, Electricity theft, AMR or ARMS (Automatic Meter Reading System), IOT (Wi-Fi) as communication, Real Time Clock (RTC),.
Paper Title: A COMPUTER BASED PROGRAM FOR RESOLVING ISSUES BETWEEN CONTRACTOR & SUBCONTRACTOR
Publisher Journal Name: IJCRT
Published Paper ID: - IJCRT2108224
Register Paper ID - 211015
Title: A COMPUTER BASED PROGRAM FOR RESOLVING ISSUES BETWEEN CONTRACTOR & SUBCONTRACTOR
Author Name(s): Ketan Bhansali, Kiran Ghorpade
Publisher Journal name: IJCRT
Volume: 9
Issue: 8
Pages: c96-c100
Year: August 2021
Downloads: 791
This paper aims to provide a solution to resolve issues in subcontracting management by developing computer based system. The computer based system is a mobile application named PRO CONTRACTOR MANAGER. This mobile application will help improve relation between contractor and subcontractor. These computer based program or mobile application will have daily project tracking, daily work done by subcontractors, amount to be paid to the subcontractor depending on work done, quality of work can be known, the attendance of subcontractors can be marked. All the members related to project can be added so that each member can know the current status of the project. Due to this mobile application overall issues between contractor and subcontractor can be reduced. The other main objective of paper is to examine the major disputes between contractor and subcontractor. The research will include collection of primary data i.e. by preparing questionnaires and secondary data by literature review.
Licence: creative commons attribution 4.0
Subcontractor, Contractor, Computer based system, Pro contractor manager
Paper Title: A REVIEW ARTICLE- ECOFRIENDLY AND ECONOMIC APPLICATIONS OF MIXED HYDROTROPIC SOLUBILIZATION IN THE PHARMACEUTICAL FIELDS OF ANALYSIS AND FORMULATIONS
Publisher Journal Name: IJCRT
Published Paper ID: - IJCRT2108223
Register Paper ID - 210946
Title: A REVIEW ARTICLE- ECOFRIENDLY AND ECONOMIC APPLICATIONS OF MIXED HYDROTROPIC SOLUBILIZATION IN THE PHARMACEUTICAL FIELDS OF ANALYSIS AND FORMULATIONS
Author Name(s): YASHI THAKUR, KHUSHBOO NAGWANSHI, SIMRAN LUDHIANI, .K. MAHESHWARI
Publisher Journal name: IJCRT
Volume: 9
Issue: 8
Pages: c81-c95
Year: August 2021
Downloads: 807
Solubility of poorly water-soluble drugs has been a really vital issue in screening studies of new chemical entities as well as formulation research. Drug efficacy can be restricted by poor aqueous solubility. Therefore, solubilization of poorly water-soluble drug is encountered on challenging factor. Poor solubility of any drug or chemical entity directly affects its bioavailability, as bioavailability is dependent on several factors like drug solubility and permeation across biological membranes. Various methodologies have been employed to enhance the aqueous solubility of poorly water-soluble drug. Hydrotropic solubilization is one of them. Hydrotropic solubilization is the process of enhancement in aqueous solubility of poorly water-soluble drugs in presence of large concentration of a hydrotropic agent or hydrotropes. Hydrotropes possess the ability to increase the solubility of drug. Various hydrotropic agents such as sodium benzoate, sodium citrate, niacinamide, sodium caprylate, sodium acetate, sodium ascorbate, sodium gluconate, urea etc., have been employed to increase the solubility of poorly water-soluble drugs. Mixed hydrotropic solubilization is a novel and advance way for enhancement in solubility of poorly water-soluble drugs by using different hydrotropic agents in small and safe concentrations to reduce the toxicities.
Licence: creative commons attribution 4.0
Solubility, Hydrotropy, Mixed hydrotropy, Hydrotropic agents, Poorly water-soluble drugs.
The International Journal of Creative Research Thoughts (IJCRT) aims to explore advances in research pertaining to applied, theoretical and experimental Technological studies. The goal is to promote scientific information interchange between researchers, developers, engineers, students, and practitioners working in and around the world.
Indexing In Google Scholar, ResearcherID Thomson Reuters, Mendeley : reference manager, Academia.edu, arXiv.org, Research Gate, CiteSeerX, DocStoc, ISSUU, Scribd, and many more International Journal of Creative Research Thoughts (IJCRT) ISSN: 2320-2882 | Impact Factor: 7.97 | 7.97 impact factor and ISSN Approved. Provide DOI and Hard copy of Certificate. Low Open Access Processing Charges. 1500 INR for Indian author & 55$ for foreign International author. Call For Paper (Volume 12 | Issue 7 | Month- July 2024)