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INTERNATIONAL JOURNAL OF CREATIVE RESEARCH THOUGHTS - IJCRT (IJCRT.ORG)
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THE RELATIONSHIP BETWEEN RECURRENCE RATE AND MOLECULAR SUBTYPES OF BREAST CANCER IN PATIENTS WITH LOCALLY ADVANCE BREAST CANCER (LABC) POST MASTECTOMY AT RSUD DR. SOETOMO (FOCUS ON COMPARISON OF LUMINAL A AND LUMINAL B)
Authors
Eric Hartoyo Salim,Eddy Herman Tanggo,Dwi Hari Susilo
Downlaod Center
Keywords
breast cancer, Luminal A, Luminal B, locally advance breast cancer (LABC), recurrence
Abstract
Background: Breast cancer is the highest prevalence of malignancy for women in Indonesia and important national health problem. Several studies on gene expression have shown several subtypes of breast cancer, including the two most important subtypes, Estrogen Receptor (ER) positive (Luminal A and Luminal B) and ER negative (Triple negative and Her2 positive).
Method: The research design is an associative test using a retrospective cohort observational analytical study design, associating the relationship between tumor subtypes with recurrence in locally advanced breast cancer patients after mastectomy and has received additional therapy according to standard procedures at Dr. Soetomo Surabaya This study used secondary data from the medical records of the Oncology Polyclinic, RSUD Dr. Soetomo Surabaya from 2014 to 2019.
Results: The research subjects who have been selected according to inclusion criteria are 214 people, with the proportion in the population of luminal A and luminal B subtypes of 107 people each. Based on this study, the authors found that the subtype was positively correlated with recurrence in LABC patients who had undergone mastectomy with a significance value of p = 0.000 (p <0.05; 99% CI).
Conclusion: According to this study, there is a relationship between the recurrence rate and the molecular subtype of breast cancer in locally advanced breast cancer (LABC) patients after mastectomy at Dr Soetomo Hospital.
IJCRT's Publication Details
Unique Identification Number - IJCRT2108254
Paper ID - 211097
Author type - Foreign Author
Page Number(s) - c362-c371
Pubished in - Volume 9 | Issue 8 | August 2021
DOI (Digital Object Identifier) -
No Of Downloads - 719
Author Country - Indonesia, 60112, Surabaya, Surabaya, 60112, Humanities All
Publisher Name - IJPUBLICATION | www.ijcrt.org | ISSN : 2320-2882
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Eric Hartoyo Salim,Eddy Herman Tanggo,Dwi Hari Susilo, "THE RELATIONSHIP BETWEEN RECURRENCE RATE AND MOLECULAR SUBTYPES OF BREAST CANCER IN PATIENTS WITH LOCALLY ADVANCE BREAST CANCER (LABC) POST MASTECTOMY AT RSUD DR. SOETOMO (FOCUS ON COMPARISON OF LUMINAL A AND LUMINAL B)", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.9, Issue 8, pp.c362-c371, August 2021, Available at :http://www.ijcrt.org/papers/IJCRT2108254.pdf
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