ISSN Approved Journal No: 2320-2882 | Impact factor: 7.97 | ESTD Year: 2013
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 7.97 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)
IJCRT Journal front page | IJCRT Journal Back Page |
Paper Title: ANTHRACENE DERIVATIVES AS ANTI BREAST CANCER
Publisher Journal Name: IJCRT
Published Paper ID: - IJCRT21X0046
Register Paper ID - 222652
Title: ANTHRACENE DERIVATIVES AS ANTI BREAST CANCER
Author Name(s): Mr. Vijay Vinayak Pawar
Publisher Journal name: IJCRT
Volume: 10
Issue: 7
Pages: d189-d362
Year: July 2022
Downloads: 453
New potential chemotherapeutic strategies are required to overcome multidrug resistance (MDR) in cancer. In this study, Antibacterial activities of the synthesized compounds were evaluated against gram (+) Staphylococcus aureus and gram (-) Klebsilla aerogenes by measuring zone of inhibition. The antifungal activities of the synthesized compounds were evaluated against Candida albicans by disc diffusion method. Compounds screened for antibacterial activity against Bacillus subtilis, Escherichia coli. and antifungal activity against Candida albicans, Aspergillus Niger by cup plate method. All the compounds of the series were screened for their antibacterial and antifungal activity studies. Substitution of hydroxyl and halo groups emerged as active in both antibacterial and antifungal screening. The reported antibacterial activity of 3-benzoyl-2-oxo/thioxo-1, 2, 3, 4-tetrahydropyrimidine analogues. 5-Acyl-6-methyl-4-substituted-2-oxo/thioxo-1,2,3,4-tetrahydropyrimidines were synthesized by cyclocondensation reaction between appropriate aldehyde, acetoacetate and urea/thiourea in presence of aluminium chloride and hydrochloric acid which upon treatment with benzoyl chloride in presence of aluminium chloride in presence of pyridine in benzene furnish the title compounds. The compounds have been tested for antibacterial activity against staphylococcus aureus
Licence: creative commons attribution 4.0
Breast cancer, antibacterial, NMR
Paper Title: PREPARATION & OPTIMIZATION OF ANTIFUNGAL NOVEL TOPICAL DRUG DELIVERY SYSTEM
Publisher Journal Name: IJCRT
Published Paper ID: - IJCRT21X0045
Register Paper ID - 222930
Title: PREPARATION & OPTIMIZATION OF ANTIFUNGAL NOVEL TOPICAL DRUG DELIVERY SYSTEM
Author Name(s): Rupali Solanke, Jaiswal Nareshkumar, Chavan Gitanjali, Priyanka Zendekar
Publisher Journal name: IJCRT
Volume: 10
Issue: 7
Pages: d141-d188
Year: July 2022
Downloads: 405
The present study is to optimize and characterize a Nanostructured Lipid Carrier (NLC) loaded transdermal drug delivery system loaded by antifungal drug. The goal of this research is to optimize the NLCs and to study its potential for the topical delivery of Luliconazole by prolonging the drug release through the NLC transdermal gel. Preformultion studies for the drug and excipients studies are carried out by IR. Pre-optimization studies were carried out for the selection of suitable formulation variables from lipids, surfactant and process variables from ultrasonication time. From the selected variables, 15 NLC formulation were designed by using Solvent diffusion technique and optimized based on the impact of independent variable on dependent variables like Particle Size and percentage Entrapment Efficiency (% EE) by applying Box- Behnken design utilizing multiple linear regression method (Design expert software). The selected optimized NLC formulation was fabricated into transdermal gel. It was evaluated for viscosity, Drug content, pH, Spread ability and In vitro diffusion studies.
Licence: creative commons attribution 4.0
Nanostructured Lipid Carrier (NLC)
Paper Title: ASSESSMENTOFSTRUCTURALSTABILITYOFBUILDINGS
Publisher Journal Name: IJCRT
Published Paper ID: - IJCRT21X0044
Register Paper ID - 223056
Title: ASSESSMENTOFSTRUCTURALSTABILITYOFBUILDINGS
Author Name(s): Mohd Irshad
Publisher Journal name: IJCRT
Volume: 10
Issue: 7
Pages: d67-d140
Year: July 2022
Downloads: 412
After the incident of a sub station building collapse in our organisation, the department has decided to check the structural stability of the old buildings which were constructed before the year 2000. We have performed the NDT tests to assess the health of the buildings and every thing is recorded. This paper is based on this project.
Licence: creative commons attribution 4.0
Paper Title: PERFORMANCE AND ANALYSIS OF COIR FIBER AS A SOIL REINFORCEMENT
Publisher Journal Name: IJCRT
Published Paper ID: - IJCRT21X0043
Register Paper ID - 222534
Title: PERFORMANCE AND ANALYSIS OF COIR FIBER AS A SOIL REINFORCEMENT
Author Name(s): VIRENDER KUMAR, TAUHEED RAMEEZ
Publisher Journal name: IJCRT
Volume: 10
Issue: 7
Pages: d1-d66
Year: July 2022
Downloads: 502
The increasing tempo of construction activity has led to the requirement of good soil whose availability is less hence, there is need of improving the soil condition which can be accomplished through ground improvement methods. Among all the ground improvement techniques, soil reinforcement is emerging as an attractive alternative. The addition of natural fibre to the soil is very good soil reinforcement technique. Coir fibre extracted from the outer shell of the coconut can be effectively used to tackle many short term stability issue in geotechnical engineering. Coir fibre having high lignin content and less cellulose content than fibres such as flax and cotton, which makes it stronger but less flexible. Coir is bio-degradable product and it takes approximately 20 years to degrade over the ground and with suitable coating takes about 4-5 years to decompose under the burial condition. It is moth-proof, resistant to fungi and rot, provide excellent insulation against temperature and sound, not easily combustible, flame-retardant, unaffected by moisture and dampness, tough and durable, resilient, spring back to shape even after constant use and have low thermal conductivity and bulk density. The present study is focussed on modifying the geotechnical properties of soil by reinforcing it with different percentages of coir fibre in the soil obtained from the Gautam Budh Nagar region of District, Delhi NCR. For this study coir fibre was purchased from the local market of New Delhi. The study is conducted in two phases. In the first phase, the geotechnical properties of soil were studied by conducting laboratory tests. In the second phase, soil mixed with four different percentages of coir fibre i.e., 0.25 %, 0.50%, 0.75%, and 1% were subjected to various tests.
Licence: creative commons attribution 4.0
Performance and Analysis of Coir Fiber as a Soil Reinforcement
The International Journal of Creative Research Thoughts (IJCRT) aims to explore advances in research pertaining to applied, theoretical and experimental Technological studies. The goal is to promote scientific information interchange between researchers, developers, engineers, students, and practitioners working in and around the world.
Indexing In Google Scholar, ResearcherID Thomson Reuters, Mendeley : reference manager, Academia.edu, arXiv.org, Research Gate, CiteSeerX, DocStoc, ISSUU, Scribd, and many more International Journal of Creative Research Thoughts (IJCRT) ISSN: 2320-2882 | Impact Factor: 7.97 | 7.97 impact factor and ISSN Approved. Provide DOI and Hard copy of Certificate. Low Open Access Processing Charges. 1500 INR for Indian author & 55$ for foreign International author. Call For Paper (Volume 12 | Issue 7 | Month- July 2024)