Volume 11 | Issue 6

 Abstract

The need of regulation of the Real Estate Market arose from the increasing malpractices in the real estate market where the consumers had to bear a lot of risks such as delayed delivery, title of the property, quality of the facilities provided, and necessary changes etc. before they decide to purchase. The Real Estate Regulation (Development and Authority) Act, 2016 came up with a primary objective to restore the faith of consumers by regulating the business practices and transactions in real estate sector. This whole standardization procedure involved establishment of Real Estate Regulatory Authorities at state level for facilitating the development of the real estate sector and a customer-oriented procedure wherein the interests of the customers cannot be harmed. Now the risk borne by the customers is transferred to the developer. Provision of an escrow account, no advertisements allowed without registration with RERA, punishments and compensations in case of delayed delivery, etc. left no room for developers to absorb the other costs incurred by them so they may be transferred on the customers by the way of price increase. Instead of increasing the sales, price hike of 40 per cent within a week of enforcement in some states, led to the decrease in total sales, which were already soaring due to Demonetization. There were other challenges faced by the States in establishing the Regulatory Authority as per the central Act and a lot of controversy occurred in respect of penalties, wherein some states did not enforce the penal provision in their subsequent Act and Rules for enforcement of RERA.

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RERA, Problems, Prospec

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Electrical energy demand is increasing in accordance with rapid growth of the human population. Since fossil fuels is the most widely used energy source, thus it is depleting very fast. Alternative energy source is urgently needed to replace the use of conventional energy sources. Perpetual Motion Machine (PMM) which can be applied to produce electricity, may be an alternative solution for the problem the world is facing today. The machine is designed to generate power from repulsive forces of permanent magnet without utilizing external sources. Some researches had conducted experiments and Neodymium magnet is most used in the project due to its strong magnetic field. The device is mainly built using a permanent magnet, a rotating wheel and a generator. This paper reviews some aspects on how A Perpetual Motion Machine (PMM) generates electrical power. The aim of the paper is to provide a summary of the topic and its opportunities in further enhancements for better results. The study found that the concept is very effective, ecofriendly and less space needed. However, a larger scale development of the machine along with proper magnet and gear arrangement is currently needed for a better performance and application.

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 Keywords

Perpetual motion machine, Electricity , Mechanical energy , Magnet , Rotor , Efficient , Clean Energy

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standards, management, emergencies, neonatal, intensive care units.

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Bumetanide (BUM), UV-Vis Spectrophotometry, ICH guideline, Absorbance maxima, Area under curve, Validation parameter.

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Gemfibrozil, UV Vis Spectrophotometer, Absorption maxima, AUC, ICH, %RSD

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RP-HPLC, Agilent, Benidipine, ICH, LOD, and LOQ.

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Duloxetine hydrochloride, Span, Proniosomes, Improved bioavailability, Topical drug delivery.

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Preterm new born are babies born before 37 weeks of gestation are known as preterm babies. Preterm newborns experience stress from the moment they are born in the Neonatal Intensive Care Unit. The aim of the study is to assess the effectiveness of cluster care on physiological Parameters and level of comfort among preterm neonates admitted in NICU at SMVMCH, Puducherry. To assess the physiological parameters, and level of comfort before and after cluster care among preterm neonates, to evaluate the effectiveness of physiological parameters, and level of comfort among preterm neonates before and after administration of cluster care and to associate the effectiveness of clustered care on physiological parameters and level of comfort among preterm neonates with their selected demographic variables. A Quantitative research approach and Pre - experimental design (one group pre and post-test) research design was adopted for this study. Totally 30 preterm neonates admitted in NICU at Sri Manakula Vinayagar Medical College and Hospital were selected for the study. The collected data was analyzed in terms of both descriptive and inferential statistics. The collected data was analyzed in terms of both descriptive and inferential statistics. The findings reveal that the paired "t" test value of level of comfort in pre-test is "t" = 0.714, and p<0.481. In the post-test was "t" = 15.542 and p<0.000 respectively. Hence the cluster care on level of comfort is significant.

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Cluster care, Level of comfort, Physiological parameters, preterm neonates

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Pteridophytes are one of the oldest and primitive vascular plant groups on the earth. Tectaria coadunata belongs to the family of Dryopteridaceae. Tectaria coadunata (Wall. Ex Hook & Grev.) C. Chr (Kukkutnakhi) is used by many Vaidyas in hyperlipidemic conditions and obesity. The dried extract of rhizomes of Tectaria coadunata has various bioactivities such as antioxidant, antimicrobial and anti-inflammatory. The physicochemical analysis includes Total Ash, Water soluble Ash, Acid soluble Ash and Total Ash. The quantitative phytochemical includes Total Tannin, Total Alkaloids and Total Flavonoids. The present investigation was undertaken to study the presence of secondary metabolites, and physicochemical analysis from rhizomes of Tectaria coadunata.

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Tectaria coadunata, Physicochemical and Quantitative Phytochemical analysis

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Artificial intelligence (AI) has made significant strides in the field of healthcare, from patient identification and treatment to drug innovation and exploration. Technologies based on AI (artificial intelligence) have an opportunity to alter healthcare, eventually improving the treatment of patients through strengthening preciseness, efficacy, and cost. This analysis considers how AI is influencing medicine, including its advantages and drawbacks. The potential of AI in healthcare to assess enormous volumes of individual patient data and offer individualized treatment regimens is one of the technology's key advantages. The ability of AI-driven diagnostic systems to identify conditions like malignancy and Alzheimer's disease has also demonstrated encouraging outcomes. However, issues like confidentiality of patient information and prejudice in algorithms raise ethical questions concerning the use of AI in healthcare. Additionally, regulatory monitoring is required to guarantee the security and efficacy of AI-based medical equipment. Artificial intelligence (AI) has the potential to speed up the procedures of bringing innovative medicines to commercialization.

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Artificial Intelligence, Machine Learning, Healthcare, deep neural networks

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Background: A surgical incision is easier to repair than a spontaneous irregular or extensive tear. An episiotomy helps to shorten the 2nd stage of labour. It can also decrease trauma to the vaginal tissues. The episiotomy wound is sutured immediately after 3rd stage of labour under local anesthesia. According to the modern science get advanced with new antibiotic local application and oral antibiotics are advised for wound, but their resistance increases day by day. Considering all the problems during Sutikavastha (postnatal period) with Yonivrana (episiotomy wound ), it is necessary to give proper treatment and assurance to the patient. Episiotomy wound can be compared with Saddhyovrana(fresh wound). So it can be treated as Sadhyovrana Chikitsa (fresh wound treatment). In this present case study, Patient with sutured surgical episiotomy wound with chromic catgut no. "0" and "1",following delivery was selected. Drugs Saptavinshatiki Guggulu and Nimbadi Lepa(Nimbadi ointment) were administered oral and local respectively in a 29 year old second gravida patient for 2 weeks and follow-up for 1week. Assessment was done on the basis of REEDA scale and Numeric Rating Scale. Result: 100% result was found in pain, edema, discharge, redness and tenderness in episiotomy wound.

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Sutikavastha, Saddhyovrana, Episiotomy wound, Vrinashodhana, Nimbadi Lepa.

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BACKGROUND: Walking is one among the common and primary movement performed by human. For maintenance of health, the physical activity should be in moderate intensity. For walking, it includes at least 100 steps/minute, equivalent to approximately 3,000 steps per half an hour.patients with lower back pain repeatedly complain of difficulties in walking, and usually walks slower than healthy peers1low back pain is one among the most important causes of morbidity in all countries of the world, and 80-85% of the people experience lower back pain at least once during their lives, lifetime prevalence of lower back pain is between 43-51% Mechanical lower back pain refers to back pain that arise intrinsically from the spine, intervertebral discs, or surrounded soft tissues. This include lumbosacral muscle strain, herniated disk, lumbar spondylosis, spondylolisthesis, vertebral compression fracture, and acute or chronic traumatic injury kinesiotaping is utilized for a wide range issues, such as musculoskeletal system, neurological and vascular problems 2,3 kinesiotape also decreases pain by stimulating the neurological system, restores muscle function by supporting weakened muscles removes congested lymphatic fluid or haemorrhage under the skin, and corrects joint misalignment by reducing muscle spasm. therefore, this study investigated the effects of kinesiotaping in patients with chronic lower back pain due to lumbar disc herniation, spondylolysis, spondylolisthesis, infection, tumor, fracture etc4. OBJECTIVES: To review the effectiveness of kinesiotaping along with physiotherapy management for patients with spatiotemporal changes in chronic mechanical lower back pain patients. The objective of this study is to find the effectiveness of kinesiotaping along with physiotherapy management for correcting spatiotemporal parameter changes in patients with chronic mechanical lower back pain. SEARCH METHOD: PubMed, Google Scholar, Research gate, and Science direct were the databases used to search papers.The title,abstract,and full text literature were used to find and screen all potential pertinent studies.To determine the availability of further papers, the citations and references of pertinent articles were also checked. SELECTION CRITERIA: Selection criteria included the articles focused on ?spatiotemporal changes in chronic mechanical lower back pain ?Kinesio taping for the treatment of low back pain ?Kinesio taping for the treatment of disability in lower back patients RESULT: Out of xxxx articles xx articles are stating that kinesio taping is beneficial for giving best results in chronic mechanical lower back pain by reducing pain, disability an increase in range for people who are having mechanical lower back pain. and xx articles are stating that there is no significant difference between kinesiotaping group and control group CONCLUSION: After a detailed review out of xx articles I conclude that kineso taping is more beneficial in mechanical low back population to reduce pain, increase range of motion, disability, and provide strength and support to maintain posture correct the muscle alignment for maintaining spatiotemporal changes than other therapies.

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Spatiotemporal parameters, chronic mechanical lower back pain, Kinesio taping

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 Abstract

In Carpal Tunnel Syndrome (CTS), compression and ischemia of the median nerve are causedeading to pain and paraesthesia as it courses through the hand. Neural tissue mobilization techniques help reduce pain and improve the functioning of the patient. The aim of this literature review is through recent studies to outline the effect of neural tissue mobilization techniques on pain and functioning in patients with median nerve entrapment in mild to moderate CTS.

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Carpal tunnel syndrome, median nerve, manual therapy, neurodynamic techniques, mobilization

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Indole alkaloids are well characterized for various activities. Meanwhile, this situation scenario of disease depicting a different story, urge a call for novel scaffolds and pharmacophores. Indole scaffold has been found in several important synthetic drug molecules which gave a valuable idea for treatment and binds with high affinity to the multiple receptors helpful in developing new helpful derivatives.

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Antimicrobial activity, anticancer activity, Antibacterial Activity, Antifungal Activity.

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This paper deals with methods and techniques of waste water management. It outlines the importance of decentralized approaches to waste water management and options for decentralization waste water treatment. This paper makes a special note on anaerobic treatment of waste water, waste stabilization ponds and constructed wet lands. This paper highlights the constraints in waste water management. This paper concludes with some interesting findings along with appropriate policy suggestions.

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Quality, Improvement, Management, Sustainability, Treatment, Wastewater

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The recent advance in nanotechnology has lead to the development of targeted drug delivery system. The ideal delivery systems solubilize the drug, lead the therapy to the target site to fulfill the individual need of patient and disease stage. Effective targeted drug delivery to specific sites is the significant problem which is being faced by the researchers. The discovery of nanosponges has become a significant step in overcoming certain problems such as drug toxicity, poor bioavailability and release of drug in a predictable fashion as they can accommodate both hydrophilic and hydrophobic drug. Nanosponges exhibit a porous structure in nature which has the unique ability to entrap the drug moieties and offers a merit of desire release. Nanosponges are tiny sponges that can circulate in the body to reach the specific site and binds on the surface to release the drug in a controlled and predictable manner. Nanosponges technology has been explored widely for the delivery of drugs for oral administration, topical administration and parenteral administration.

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Nanosponges, Targeted drug delivery, Characteristics, Method of preparation, Application

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 Abstract

Microalgae are autotrophic microorganisms that live in marine, freshwater, and soil habitats and generate organic compounds from photosynthesis. Because of its high metabolic flexibility and adaptability to varied growing environments, integrated approaches for its cultivation are currently being developed with the goal of isolating various biologically active compounds in order to boost the profitability of algae production. The number of studies on their potential use as a source of biologically useful compounds is gradually increasing. Their extraordinary potential for CO2-fixation additionally demonstrates their critical importance in sustaining Earth's ecosystems. Furthermore, they play an important role in the removal of pollutants from different environments. In addition to ecological benefits, many micro algal species have great nutritional value and produce valuable bio-products like Pigments, lipids, bioactive chemicals, specific polysaccharides, bio-hydrogen, and even bio polyesters with plastic-like characteristics have the potential for market success. The review focuses at the main parameters (temperature, pH, component composition) that influence the biomass growth process and the production of biologically active substances in microalgae. An examination of various methods for isolating and producing the main biologically active substances of microalgae (proteins, lipids, polysaccharides, pigments, and vitamins) are presented and new technologies and approaches aiming for using microalgae as promising ingredients in value-added products.

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Micro algae, Biomass, Bio-product, Pollutants, Plastic-like.

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 Abstract

Darjeeling, the northernmost district of the state West Bengal, India is believed to be a colonial product. No wonder, Lt. General Goerge Alymer Lloyd, the British officer is considered as the discoverer of Darjeeling. The pre-colonial history of Darjeeling is shredded in referential notes as a contested land. It was only after the formation of nation states that the borders were aptly considered. Before that the feudal monarchy was least bothered with frontiers rather subject and revenues were the only concern. Therefore, right from the conquest, formation and to the early developments, Darjeeling owes a major chunk of tribute to British regime, irrespective of colonial objectives. Likewise, colonial designs would not have turned into reality without adequate human hands, which were those of migrants. The study aims to understand the pattern of migration in Darjeeling hills over a period of almost two centuries, early nineteenth to early twenty first century. The very fact that Darjeeling was not just a colonial product but also a sum total of those laborious hands who worked for their masters, remains main consent of the study. Studies say economic factor remains the major force for driving migrants (Ullah, 2022). Seemingly, Darjeeling attracted thousands with a promise of better tomorrow. While few returned to their land of origin majority stayed back to give a drastic boon to the demography. In their language Darjeeling was referred to as 'Mughlan' a place where money sprouted out of tea leaves. Today, almost after 200 years of discovery, 2 million inhabitants of Darjeeling are in search of a new 'Mughlan'. 'Two leaves and a bud' no longer sprout cash rather has become an undeniable agency of exploitation. Tea 'coolies' are crying every day for their rightful demands. Two hundred years back, the hill had dreams to offer but unfortunately today people chase their dreams in distant land. Hence, the study ahead aims to dwell into the story of this transition.

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Migration, Transition, Darjeeling hills, New Mughlan

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A country is not just a piece of land, or a place bounded by its geographical boundaries.Country is a place of latent desire in the mind and heart of man.To me country is a man for a man - where division by political, geographical, communal forces is not possible. Today, memories of Bengali es are still dreaming that 'my land is very beautiful' - that beautiful country, evergreen country has been divided by for what? Partition created the worst condition of Bengalis as a nation, at the same time it left women alone and helpless. If we look at the history, we will see that women have always been victims of evolution, riots, public awakening in all countries. This discussion is about those destitute women.

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Political orientation, Division, Patriarchy, Plight and Humiliation of Women's

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In this paintings, a step-up fuzzy managed DC-DC multi-output converter is introduced with the aid of way of integrating a superb- bring Luo converter, flyback topology, and paired inductor concept. The proposed multi-output converter has extremely good output brilliant-lift form on the same time as concurrently generating step-up voltages in its outputs. The proposed step-up converter has non-isolated and one isolated output with a clean shape using one switch and one magnetic center. There is not any voltage spike through way of the leakage inductance of the coupled inductor at some point of the switch inside the proposed converter. Therefore, the transfer has low-pressure voltage. The energy inside the leakage inductor is recycled main to better overall performance in assessment to comparable converters with the coupled inductor. The walking requirements and the characteristics of the proposed converter are analyzed and noted.

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Converter, Zero-voltage switching, Photovoltaic and Sensor.

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