Volume 8 | Issue 5

 Abstract

This study includes development of RP-HPLC method for simultaneous estimation of Metformin hydrochloride and Nateglinide. The developed method was validated as per ICH guidelines in terms of specificity, Accuracy, Precision, Linearity, LOD, LOQ, Ruggedness and Robustness. The inter-day and intra-day precision results were good enough to indicate that the proposed method was precise and reproducible. The assay experiment showed that the contents of Metformin HCI and Nateglinide estimated in the tablet dosage form were free from the interference of excipients, which indicate that developed method was specific. Recovery of standard drugs added was found to be 100.07-100.82% for Metformin HCI and 101.0-102.22% for Nateglinide indicating that the proposed method was accurate. A good linear relationship was observed for Metformin HCI and Nateglinide in the concentration ranges of 10-80�g/ml and 10-80�g/ml respectively. The correlation coefficient for Metformin HCI was found to be 0.9991 and for Nateglinide was 0.9997. The LOD were 0.710 and 0.380�g/ml for Metformin HCI and Nateglinide, respectively. For Metformin HCI and Nateglinide LOQ were found to be 2.15 and 1.16�g/ml respectively. This demonstrated that developed RP-HPLC method was simple, linear, precise, accurate, robust and rugged could be conveniently adopted for the routine quality control analysis of Metformin HCI and Nateglinide simultaneously, from its pharmaceutical formulation and bulk drug.

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Metformin hydrochloride, Nateglinide, RP-HPLC, Method development, Validation

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The most purpose of this analysis is to regulate the tie up in metropolitan cities by implementing a system victimization digital technologies named as Image process and Video process with Opencv and Python from CCTV camera that brings traffic footage to be processed within the system as input. The system is predicated on the density of traffic that's to be calculated in every lane by object detection and object count at the same time. there'll be a stoplight shift rule which will adjusts the length of traffic lightweights in step with the density of traffic specified if the density of traffic is additional during a lane than different then therein lane inexperienced light are going to be of additional length and in remainder of the lanes red light are going to be of additional length. This will facilitate to scale back holdup, accidents on roads. Successively it'll offer anodyne journey to individuals and cut back energy ingestion & waiting time.

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 Keywords

Video processing, image Processing, Traffic Density condition, CCTV camera, Opencv, Python

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Abstract: Nowadays people own more than one vehicle for transportation which may cause a problem of high traffic and this will lead to road accidents which is getting increased day by day. There are many dangerous roads present across the world that are very narrow and T roads, hairpin roads, curved roads are largely seen in the ghat areas. One of the common problems that we face in ghat areas specially is the drivers are not able to see the vehicle that is coming from the other end of the curved road. And if the incoming vehicle is in great speed, it is highly impossible to control the vehicle. Hence there is much need of road safety system. To avoid this vehicle accidents in ghat areas we have proposed a vehicle accident prevention system which makes use of Arduino Board, IR sensors, LED lights, LCD display, GSM and Buzzer. When the vehicle enters from zone 1 of the curved road IR sensor senses the vehicle and turns the LED light into RED colour and raises the buzzer indicating that there is danger. And turns the LED light in to green once the vehicle comes out of the other end which is zone 2. In this way we can prevent the vehicle accidents in ghat areas.

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Keywords: Accident prevention, Arduino board, Curved roads, Ghat areas.

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Abstract�Network lifetime is the major constraint in the design of the wireless sensor network. Designing an energy efficient routing algorithm to increase the network lifetime is one of the most significant design criteria of wireless sensor networks. Various clustering techniques are used previously to augment the network lifetime. A novel routing protocol, Fixed Low Energy Clustering Hierarchy (FLECH) is proposed to achieve the increased gross lifetime of the wireless sensor network. FLECH is a hierarchical based routing that has fixed clusters and heterogeneous nodes. A cluster head is elected in each of the fixed clusters based on two attributes of nodes, energy and distance from the base station. As the event occurs the member nodes communicate the message to its respective clusters heads using Adaptive on Demand Distance Vector (AODV) algorithm. Then the cluster heads aggregate the received data and transmit it to the base station.

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AODV, LEACH

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Spinning is a majorly used technique in producing axisymmetrical parts that are produced by rotating metal sheets at a higher speed. The spinning process is carried out by two methods, one by manually and other by a CNC lathe. Components that are made by this process are mostly used in aircraft and missile industries as these units required low weight and high strength materials for the manufacturing. The various parameters to be investigated and studied from this analysis are the evaluation of various force components in all directions, surface finish, determination of blank thickness, blank diameter after the deformation, considering various spinning speeds, the formability of sheet metals, spinning ratio, spin ability, different nose radius of rollers and the diameter of mandrel, study of the process parameters like rate of feed, speed of the spindle and feed ratio. In this paper, the materials to be considered are s, copper and brass. This work is been carried through experimental investigations and finite element analysis simulation. The evaluation results are correlated with the results of finite element analysis simulation. The variation of experimental and numerical simulation will be obtained within the range of 10-12%.

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Conventional Spinning, Process Parameters, Spinnability, FEAnalysis.

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Fast advancement in computerized information obtaining procedures have prompted immense volume of information extraction of text. Most of the data is composed of either unstructured or semi-structured form of text. To make this unstructured form of data into structured form using text mining, natural language process (NLP) techniques and machine learning algorithms are used. Cancer based text are in the form of Electronic Health Record (EHR/EMR) and there are tools to extract the text. Health care and clinical practice create a lot of content manifestations, test results, analyse, medicines, also, results for patients. This clinical content, reported in wellbeing records, is a potential wellspring of information and an underused asset for improved social insurance. To improve understanding consideration, information on demonstrative, prognostic, inclining, and medication reaction markers are fundamental. In this paper explored different text mining approaches using machine learning, natural language processing and data mining techniques

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Clinical text, Machine learning, Data mining, EMR/HER, NLP

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ABSTRACT INTRODUCTION: Child labour is a global concern and �harsh reality� of the world. Poverty is an account of this �harsh reality�. Studies from an Indian constituency states that India has the highest proportion of child labourers in the current scenario and according to the studies nearly 7 percent of the child labour are responsible for a significant amount of the Gross Domestic Product. Objective: To study the psychological effects on child labour in the slum areas of Delhi. METHODS: A community based descriptive cross-sectional study was conducted among 500 child labourers in and around slum areas of Delhi. Data regarding demographic and psychological effects were recorded by using a semi-structured questionnaire. A descriptive analysis was carried out. RESULTS: The mean age of the children is 10.3 years with a range of (7-14 years). Among the 500 child labour, 41% (206) were girls and 59% (294) were boys and there were 33% (168) children who are working past one year, 31% (158) last three years, 18% (90) since 3-5 years and 17% (84) children for more than 5 years. Social issues among child labour include, 40% of the child fight a lot, 24% of the child gets extremely angry, 48% child was accused of lying and cheating, and 47% has stealing habits. CONCLUSION: In India, child labour is an important public health concern and Child labour policies and education policies have to be formulated and implement interventions that will reduce the number of child labourers.

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KEYWORDS: Psychological Effects, Child labour, and Slum areas.

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 Abstract

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doucument clustering

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Introduction: Sleep is a biological process that is essential for life and optimal health. College life can contribute to a health or disease promoting lifestyle and ultimately relate to their quality of life. Major changes in lifestyle such as unbalanced diets and lack of sleep can be detrimental to the student�s well-being. Purpose: The purpose of the present study was to provide insight into the effect of lack of sleep and dietary behavior in girls (19-22 years). Method: A cross sectional study was conducted in Dr. BMN College of home science. Total 100 students were enrolled in this study. The tools used to collect data were questionnaire and 24- hr dietary recall. The sleep quality was analyzed using Pittsburgh Sleep Quality Index (PSQI). Data collected were coded in Microsoft excel and statistical analysis was done using SPSS to interpret the result. Results: The majority of the students participated in the study have poor quality of sleep (73%) and were short sleepers i.e. sleep less than 6 hr/ night (67%) based on PSQI score. Highly significant correlation was seen between sleep quality and skipping breakfast (p< 0.05), The mean calorie and protein intake of students who participated in the study was 1224.7 kcal/d and 34.6 gm/d. Conclusion: In conclusion, Poor sleep quality leads to skipping breakfast on regular basis. There was no significant relation found between macronutrient intake and sleep quality.

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BMI, Short sleepers, Sleep quality, PSQI

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� Concrete is most generally utilized development material on the planet. Fibre strengthened cement (FRC) is a solid where little and intermittent filaments are scattered consistently. The fibers used in FRC capacity be of many materials similar steel, G.I., carbon, glass, aramid, asbestos, polypropylene, jute and so on. The expansion of these filaments into solid mass can drastically expand the compressive quality, rigidity, flexural quality and effect quality of cement. FRC has open numerous applications in structural building field. In view of the research center examination on fibre strengthened cement (FRC), solid shape and chambers examples have been structured with steel fibre fortified cement (SFRC) containing strands of 0% and 0.5% volume division of snare end Steel filaments of 53.85, 50 angle proportion and antacid safe glass strands containing 0% and 0.25% by weight of concrete of 12mm cut length were utilized without admixture. Contrasting the consequence of FRC and plain M20 grade solid, this paper approved the constructive outcome of various filaments with rate increment in pressure and parting improvement of example at 7 and 28 days, broke down the affectability of expansion of strands to concrete with various quality.

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Compressive Strength, Fibre Reinforced Concrete, Glass Fibers, Tensile Strength.

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Abstract A study to assess knowledge and attitude towards mental illness among caregivers of mentally ill client attending out patient department in selected psychiatry hospital, Goa was conducted with the objectives to a) Assess caregivers level of knowledge and attitude towards mental illness b) Find the relationship between caregivers level of knowledge and attitude towards mental illness and c) Find the relationship with caregivers level of knowledge, attitude and selected demographic variables. A descriptive survey approach was adopted. A sample size of 100 was selected using convenience sampling method. A structured questionnaire and Likert- Type scale was used to obtain the data from the respondents. Data was analysed using descriptive and inferential statistics. The findings of the study revealed that only 16% of the respondents had good knowledge about mental illness and 89% of the respondents had negative attitude towards mental illness. Results indicated the need for designing strategies to improve caregivers knowledge about mental illness

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knowledge, attitude, mental illness, caregivers

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The threat of penetrating a company's end result is a collection of actions aimed at violently misusing systems, networks, data, and resources. Preventing internal threats is not difficult, as the trusted partner of the concerned company, who allows access to those confidential services. Progressive analysis in identifying internal threat specifically focuses on retrieving methods of uncontrolled behavioral injury for detective task discomfort or abnormal changes in user behavior over time. However, the unpleasant task is that one does not earn honestly in a threatening environment. We propose an improvement logging strategy, a technology that detects internal threats from the user activity chain. Initially, a single-day selection area unit calculated from the user activity log. The array of feature attribute selectors is predefined over the data for each feature over time. Each label sets the data attribute and extracts from the truth below. The XG-boost classifier is used to classify whether the user is malicious or not, and its performance has been compared to various popular methods such as a random forest. The CMU Insider Threat Dataset is only used for internal threat notification, providing approximately 14-GB browsing logs for the general public such as logon, application connection, file transfer, and e-mail log files.

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Time series vector, XG-Boost, Malicious, Non-Malicious

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� For diagnosing eye diseases the structure analysis of structure Optic Nerve Head (ONH) and registration of retinal images are very important. So this paper proposed the 3D construction and registration of retinal images. The previous reconstruction method states disparity map estimation as a depth cue to remove uncertainty of the relative positions and then by using guided filter final depth map can be obtained. The red cyan anaglyph can be computed by using this depth map and 3D structure of ONH can be constructed.

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3D reconstruction, Optic-nerve head (ONH), Disparity map, image registration

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The area chosen was designing, a creative field that stir the imagination. Four mats were designed and construction using silk selvedge waste as the weft yarns during weaving. The main aim of the study was to find out the acceptance of designer mats woven using silk selvedge waste. The various objectives include: 1. Recycling :Utilize silk waste (selvedge) as yarns to create mats using different weaving techniques. 2. To design the mats. 3. To study the significance of 2 different techniques of construction �plain weave and tapestry weave. 4. To evaluate the acceptance of designed; plain and tapestry woven mats The acceptances evaluation was done by the mean of questionnaire method. Mats were displayed to a set population of respondents to check their acceptances. 30 respondents were the chosen sample size. The result was analyzed discussed and presented in the form of tables and graphs.. From the survey the acceptance of the mats were judged and concluded as follows: � The best design is sample C & D with 50 % respondents ranking them as excellent. � The best placement of designs was that of sample C & D with 50% ranking it as excellent. � The best mats in terms of overall appearance is sample C and D with 50% ranking it as excellent and hence the best mats of the collection with the highest excellent rating in all was sample C and D.

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Reaserch on selvedge waste

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To sustain in the market the retailers are using online and offline platforms strategically to facilitate the good shopping experience. With the fierce competition in retailing industry, the channel selection is considered as the top priority of the growing number of retailers in maintaining competitiveness. Previous studies investigate that perception of value of money, quality of the products and services and risk strongly influence apparent value and buying intentions in the offline and online platforms of shopping. This study is piloted to identify antecedents that influence online and offline preferences of young female consumers. The choice of fashion apparel is related to the self-image in case of young Indian females and to get the apparel of their choice they can opt to buy from e-tailers and retailers. With the availability of these two modes of shopping this study is attempted to identify the factors which influence the shoppers to opt for online or offline shopping for fashion apparel category and to compare online and offline buying behaviour of the females. The findings of the survey inferred that young female fashion shoppers engage with high involvement so as to get the latest designs with good quality and value for money. Understanding the expectations and behavior of these females will help the retailers in taking practical approach to facilitate good experiences of females in retail outlets by reducing the hiccups and enhancing the product and service offerings.

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Behavior, Expectations, Offerings, Offline shopping, Online shopping, Retailer

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Surveillance robot presents a contemporary approach for surveillance at remote and border area's victimization multifunctional automation supported current IOT utilized in defense and military applications. By means that of this, we tend to advance a surveillance automation which may be integrated into any reasonably home. The controller of the bot are going to be the powerful Raspberry Pi 3 Model B. A digital camera hooked up to the Pi monitors the world and sends a notification once any intrusive or obtrusion is detected. The live streaming ability of the Pi permits the camera feed to be analyzed from any location victimization net. With such a system, each user can feel a lot of protected. Associate field Raspberry pi sends a wireless command that is received on website and consequently automaton moves. Streaming is completed victimization USB camera. It contains gas sensing element and temperature sensing element so, it is often used conjointly in disaster occurred areas like earthquake, fire, etc. Gas sensing element can discover the harmful gases that are gift at the disastered space and conjointly temperature sensing element is mounted thereon thus, it will live the temperature within the fireplace accidents as early precautions to assist fireplace fighters.

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surveillance, Raspberry Pi 3 Model B, USB camera, live stream, Gas sensor, Temperature senosr

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This article has been made to review some medicinal plant used for the treating burning of skin Some herb has vital role in the prevention & treatment of burns. The burns are one of the major public Health problems in world wide. Herbal Drug effective in boiling water burn, radiations Sunburn chemicals and Fire. Self-Care with Herbal drug is most appropriate to 2st degree and 2 degree of burn Herb gives Proper treatment of burns Can reduce the complication of injury Herbal Drug used topically, they can reduce pain of burn, helps to fight infection, helps to formation of Scar tissue. the Herbal ointment is made up of different medicinal Plant parts, like alo-vera, Honey Jammun seed, arjuna sativa, & coconut oil, this Herbs give Antioxidant, antibacterial, antimicrobial, & anti-inflammatory Properties. the burn part of body is firstly recovered by Herbal ointment. The Herbal Drug do not produce allergic reaction and Side effect.

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Antibacterial, Antioxidants, Allergic Reaction Burn, degree of burn.

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The purpose of this research was to study the relationship between Mobile Phone Addiction and Academic Stress among Higher secondary students with the age group of 16-20 years of age. The sample of the study comprised of 92 students 53 males and 39 females. The students was measured by using Mobile Phone Addiction scale (MPA-S) developed by Dr.A.Velayudhun and Dr.S.Srividya which consists of 37 statements and Academic Stress developed by Dr.Uday K. Sinha and it consists of 30 statements.

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Moble phone Addiction, Academic Stress

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A businessman has to meet various kinds of customers with different attitudes and habits. Customer satisfaction is the prime investment for every businessman. Customers are having bundle of wants; the wants satisfying power of the business is not only the purchasing power of the customer but also services provided by the owner of the business. Further, it is additional burden to every businessman to follow guidelines given by the Government during this pandemic situation. Hence, this study aims to observe the mentality of customers and activities of the other customers and merchants at business centres during this pandemic situation. The study based on the primary data collected from 129 respondents through online survey using Google Forms. The study observed that out of 129 respondents; 59 (45.74 per cent) respondents are awful in following pandemic guideline when going outdoor i.e., maintain social distancing and hygienic practice at business centres and there is no respondent�s is poor in following pandemic guidelines. Fourteen (10.85 per cent) respondents opined that the other customers are not at all satisfied in following pandemic guidelines in the business centres and 12 (9.30 per cent) respondents opined that the other customers are never mind even after the merchant advised to follow pandemic guidelines. Forty-five (34.88 per cent) respondents opined that the merchants are above standard in advising pandemic guidelines to their customers and only eight (6.20 per cent) respondents justify that the merchants are poor in professional ethics during pandemic situation. The study suggested there should be more strategic awareness programs to improve social distancing and hygienic practices among the people.

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Pandemic Situation, Pandemic Guidelines, customer attitude, customer satisfaction

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 Abstract

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Literature, Lionel Verney, Alienation, Annihilation, and Compassion

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