Volume 10 | Issue 3

 Abstract

Mucoadhesive drug system interact with the mucus layer covering the mucosal epithelial surface, mucin molecular and increase the residence time of the dosage form at the site of absorption. Mucosal adhesion is backed by several theories which include electronic, absorption, wetting, diffusion, fracture and mechanical. Stages of mucoadhesion include contact stage and consolidation stage. Mucoadhesion while considering drug delivery is having several merits, because of the ideal physiochemical characters of the mucosal membrane by ionic bonds, covalent bonds, van-der-waal bonds and hydrogen bond. Various sites for mucoadhesive drug delivery system are ocular, nasal, buccal cavity; GIT, vaginal, rectal and several specific dosage forms have been reported. Factors affecting mucoadhesion are , presence of carboxylate group and density. several synthetic and natural polymers are identified assuitable candidates for mucoadhesive formulation. EX-vivo/in-vitro studies utilizing gut sac of rate provides indepth knowledge about the adhesive property of the dosage form as well as polymers.

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Bioadhesion, mucoadhesion, van-der-waal force, consolidation stage.

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The goal of this study is to study the process in the OPD of Lilavati Hospital & Research Centre. It includes Factors Affecting Patient flow, Reasons for Delay in patient flow, Ways to improve the patient flow and also Patient waiting time. The purpose of this audit is to assess patient waiting time and doctor consultation time in a Super Speciality Hospital and to formulate strategies to improve the waiting time and consultation time. The utilization of many of the other services provided by the hospital, often depend on how satisfied the patient is with the outpatient services provided. In a competitively managed healthcare environment, long waiting time of patients in an OPD adversely affects the hospitals ability to attract new increased business. It is difficult to sell services if the individuals are dissatisfied with the delayed process and increased waiting time. The service can be improved by effective communication, providing enough man power and educating patient about the importance of taking an appointment before arriving at the hospital. Because of large number of ambulant patients, an efficient and up to the mark Outpatient Department(OPD) in a hospital of critical importance. This is mainly because the cost of OPD services is less than that of IPD services.

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Outpatient Department(OPD), Patient Flow, Waiting time, Services.

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This Abstract Work life balance aims to study the extent of being able to achieve a satisfactory level of happiness in executing the responsibilities of two domains i.e., work and personal lives. Every profession experiences the challenge of achieving the right balance between the work and life. The intensity of balance varies from profession to profession and also on the industry type. In this paper, we have examined the key factors which has an influence on the work life balance of employees. Literature reviews were analyzed and key factors both from personal and work environment were identified. Factors from personal lives like demography, dependents, children, home responsibilities, leisure, societal expectations, health etc. have an influence on work life balance. Work factors like environment, boss, peers, culture, working hours, time management, multiple roles, policies etc have an definite influence on the achievement of work life balance of doctors.

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Index Terms- Work Life Balance, Family, Time Management, Work-Life Conflict, Stress

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Forensic accounting, Visual and Text analytics, employee embezzlements.

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Construction and non-construction projects both account for a large portion of Iran's yearly budget for infrastructure development. The lack of a specific system for tracking the real expenses of different operations is one of the major weaknesses of the country's management construction. Forecasting, planning, controlling, determining costs, analysing, and evaluating are all aspects of project cost management (PcM). Because of poor cost management, all of a project's components are affected by a lack of financial resources. If you need to monitor rework occurrences and make sure projects are running well, managers might be a great help to you. People's happiness and project costs are negatively affected by rework. In order to determine the true cost of rework projects, several research have been carried out. It is possible to identify three main reasons of rework: variables relating to customers, design, and subcontractors. Cost management and rework are examined in this study. Management expenses and rework factors are covered in great depth, and the right strategies for detecting and managing rework to lower the overall cost of building projects are referred to

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Forecasting, planning, controlling, determining costs, analysis, and evaluating are all aspects of project cost management

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This descriptive research explored the current practices on internationalization, the issues, and problems encountered, and the perceived benefits and/or opportunities in internationalization of State Universities and Colleges in Region 3. Moreover, upon the recommendation of the CHED IAS Director the study involved eleven (11) Internationalization Directors/Heads, and 110 deans 110 students. Based on the results of the study, majority of the participants have a growing interest to pursuing internationalization in terms of mobility for teaching and learning, Institutional Partnership, social engagement and governance and leadership. However, practices on promoting internationalization in terms of research collaboration should be further improved. The researcher proposed a Comprehensive Institutional Internalization Program which could help the university administrators, CHED, higher education sector and internationalization key players in advancing and promoting internationalization. They may adopt and/or adapt this program to guide them in their decision-making, and to prepare them in venturing to any internationalization program.

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Internationalization. Practices, SUCs, Region III

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It was difficult to compare the three most active banks in Bagalkot District's public, private, and cooperative sectors. The three banks being investigated are public, private, and cooperative. It's important to note that each of the banks is a pioneer in its area. HDFC Bank is the market leader in home loans, while SBI Bank is the market leader in retail banking and BDCC Bank is the market leader in small finance.

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E banking, technology, internet, services, marketing, sbi, hdfc, bdcc

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Dhamma, Vipassana, Nibbana

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Pharmaceutical product quality has always been a major source of worry for regulatory organisations around the world. Maintaining medication quality is critical since drugs and pharmaceutical items are provided directly to customers, and poor medicine quality is not only a health threat, but also a waste of money for both the government and individuals. As a result, the pharmaceutical industry's most significant goal is to adopt an effective quality policy. Total quality management (TQM) can efficiently attain quality. TQM plays an important role in the pharmaceutical sector, from the inception of the industry through the safety of the marketed drug till it is consumed. Total quality management is a multifaceted approach that entails adhering to quality standards in all aspects of pharmaceutical manufacturing. The purpose of this review is to provide a broad overview of the TQM concept and the many management strategies that contribute to pharmaceutical quality improvement. This review paper presents a quick overview of how various techniques and practises, such as the numerous regulatory criteria that lead to the practical application of this concept include quality by design, quality risk management. This review study will assist new researchers in gaining an understanding of overall Quality Management, since it discusses QMS, cGMP, Regulatory Guidelines, TQM, and ICH Guidelines. In addition, this article provides a brief overview of current TQM industrial practises as well as the various opportunities for technical breakthroughs in real-time quality management to improve TQM outcomes.

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Quality management system, Total quality management (TQM), Good Manufacturing Practices (GMP), Quality by design, Quality risk management (QRM), ICH (International Conference on Harmonization).

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Caesarean section, health institution, Public and Private, Demographic, districts, Andhra Paresh, India

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In most recent couple of a few years, there has been a unprecedented advancement in understanding the biochemical and cell occasions of typical injury recuperating. Healing is survival mechanism and represents a trial to take care of normal complex body part and performance. All the Traditional systems of medicine, Ayurveda, Siddha and Unani describe applications of medication of plant, mineral and animal origin to treat and heal wounds. Herbal drugs induce healing and regeneration of lost tissue by number of mechanisms, starting with hemostasis, Inflammation, Tissue growth to Tissue remodelling.The present article is a trial to focus on some selected Indian ethno-medicinal plants having wound healing properties.After collecting information, further data processing and analysing of data on the different species of plant was done. Beside this review also emphasis on role of plants in antioxidant, anti-inflammatory and hemostatic activities of selected plant species.

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Keywords : Wound healing, Haemostatic, Inflammation, antioxidant.

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Microgravity, neurovestibular, Ocular, Respiratory, cardiovascular, musculoskeletal, bone metabolism, circulatory, Immune system, Bed rest.

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Key words: Women entrepreneurs, Social inclusion, Society, Economy, Development.

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Education is a major factor to achieve sustainable human development in any country; and improve the quality and achieve equity are the two main goals of any educational reforms (Alaraji, 2016). In this era of technological and information revolution, the progress of any nation depends solely on the quality of education. The 21st century teachers are expected to learn modern technologies, go global, go ahead in social settings and build positive digital footprints (Odebode, 2018). The covid pandemic situation had shook the world severely and has demanded for a revamp from traditional offline mode of teaching to online mode. The present study is a reflection on job satisfaction and job stress of primary school teachers in Kerala during covid-19 pandemic period. A survey was conducted on a sample of 32 primary school teachers in Kerala. The investigator obtained different opinions with respect to different components of the variables under study. With respect to components of job satisfaction like physical facilities, rapport with students, the teachers expressed dissatisfaction, but with respect to the components like satisfaction with authorities, satisfaction with social status and family welfare, relationship with co-workers, teachers were found to be more satisfied. The components -intrinsic aspect of the job, promotional avenues and services conditions, institutional plans and policies were found to be unaltered. Job stress with respect to the components-responsibility, powerlessness, working conditions, personal inadequacy and lack of motivation, are found to be increased. The components of job stress like work relationships, work load, role ambiguity, groupism and external pressure were found to be decreased. The negative impacts on job satisfaction and job stress can be attributed to the unavailability of facilities required for teaching in an online platform and increase in over interference of parents. The positive impacts might be due to the decrease in additional works assigned to teachers, increased recognition for their work and better relationship with co-workers. The study throws light to the fact that an effort from the government and policy makers to provide adequate digital facilities might improve the satisfaction and decrease the stress level of teachers.

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Job satisfaction, job stress, psychosocial variables, primary schools, covid-19 pandemic.

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The present study is made on A Study about Consumer Preference on Online Shopping in the Coimbatore District. Cluster and convenience sampling methods were applied to select the sample size as well as the area. Structured questionnaire was used with the sample size of 100 respondents, out of that 45 responses were received properly and the period of the study was from November 2021 to February 2022. For the data analysis simple percentage was used. The analyses were made with the help of simple percentage and Chi- Square. The final result was given in the findings, suggestion and conclusion.

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Online Shopping, Consumer Preference, Mostly Preferred Website, Satisfaction Level

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A pandemic is not a novel occurrence in human history; mankind has faced numerous pandemics throughout history. Pandemics are characterised by their severe negative consequences on the global economy. COVID-19 has been shown to have an impact on the entire food supply chain, from the field to the consumer, in one of the most vital areas of the economy. There is presently substantial worry regarding food production, processing, distribution, and demand in light of recent issues in the food supply chain. Workers' mobility limitations, changes in consumer demand, the closure of food production facilities, restricted food trade laws, and financial pressures in the food supply chain all resulted from COVID-19.Financial assistance should be provided to small farmers or vulnerable populations. Facilities should adjust working conditions and implement safety measures to protect employees' health and safety. To avoid an increase in food prices, food protectionist policies should be avoided. Finally, each country must recognise the gravity of the issue and may need to tighten or loosen precautions in response to the pandemic's spread. The food supply chain's supply network should also be flexible enough to adjust to difficulties. The goal of this analysis is to assess COVID-19's impact on the agriculture and food sectors, as well as to highlight the recommendations needed to mitigate and contain the pandemic's effects.

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COVID- 19, Pandemic , Food supply Chain, Food Industry , Consumer Behavior , Online Food shopping

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Political and economic governance are equated in the Arthashastra. Economic governance is the goal, while political governance is the means. However, as economic goals are not achieved in the absence of political goals,'Political governance becomes the goal, while economic governance becomes the means.''The aim justifies the means,' according to Kautilyan and others. The philosophy of Machiavellian. According to them, political power and material prosperity go hand in hand.The means and purposes of government are Kautilya. Good governance is also important.Whether political or economic, it all comes down to justifying the aims and means.economic and political circumstances The importance of good governance cannot be overstated.Administration in the Kautilyan sense. Considering the numerous governance scandals, that are unearthed almost every day in India, an Arthashastra reading, and imbibing.

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KEYWORDS - E - Commerce, Digital Marketing, Arthashastraa, Economic Administration, Indian Economy.

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 Abstract

SHIKSHAK PRASHIKSHAN (KARYAKRAM) PRAYOGATMAK KE SANDARBH MEIN AANE VALI PRAMUKH SAMASYAON KA ADHYAYAN

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SHIKSHAK PRASHIKSHAN (KARYAKRAM) PRAYOGATMAK KE SANDARBH MEIN AANE VALI PRAMUKH SAMASYAON KA ADHYAYAN

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This article overviews classification of nanocomposite according to their matrices, reinforcement, dimensional morphology and on the basis of their method of synthesis. . Nanocomposites are multiphase materials with one or more phases in nanoscale dimensions Nanocomposite materials have emerged as suitable alternatives to overcome limitations of microcomposites and monolithics Nanocomposites, a high performance material exhibit unusual property combinations and unique design possibilities. Being environmentally friendly, thermally stable and mechanically strong applications of nanocomposites offer new technology and business opportunities for several sectors of the aerospace, automotive, electronics, biomedical, tissue engineering, wound healing, drug delivery, gene therapy and food packaging .Nanocomposites themselves encompass a very broad category of materials. The classification of nanocomposites according to their matrices shows the existence of three main categories of materials: metal matrix, ceramic matrix and polymer matrix nanocomposites. On the basis of reinforcement nanocomposites are classified as fibre, laminar and particulate reinforced nanocomposites. According to the dimensions nanocomposites may be classified as nanoparticles, nanotubes, nanowires and layered silicates

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Nanocomposites, matrix, polymer, nanoparticle.

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Spinal muscle atrophy (SMA) is an autosomal recessive and neurodegenerative disease caused by homozygous mutations in the survival motor neuron1(SMN 1) gene. SMA isdistinguished by motor neuron degeneration, which is a resulting in weakness and increasing muscle atrophy. Children with a most severe form of SMA there were not able to sit independently.There was only 8% of children would survivebeyond their 2years of age without permanent ventilation support. One of these therapies, Onasemnogene abeparvovec, a gene replacement therapy based on the adeno-related virus, is a one-time intravenous infusion in which it delivers human function SMA. Inadditionto significantly improving survival, Onasemnogene Abeparvovec increases motor function and reducesthe need for respiratory or nutritional support in many patients. Recommendations of Dosage and administration. Recommendations for Prophylaxis of prednisolone tapering and monitoring for potential adverse events, including hepatotoxicity, Elevated Troponin -I thrombotic microangiopathy, are described here. Table 1.1Demonstrates a sample for post-treatmentmonitoring. It also describes the Postmarketing experience, drug interactions and their use in a specific population,and even temporary vector shedding and waste handling.

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Gene therapy, Onasemnogene abeparvovec, efficacy, safety, spinal muscular atrophy

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