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INTERNATIONAL JOURNAL OF CREATIVE RESEARCH THOUGHTS - IJCRT (IJCRT.ORG)
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IJCRT Peer-Reviewed (Refereed) Journal as Per New UGC Rules.
ISSN Approved Journal No: 2320-2882 | Impact factor: 7.97 | ESTD Year: 2013
Call For Paper - Volume 13 | Issue 11 | Month- November 2025
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Paper Title: In Silico Designing, Validation and In-Vitro Synthesis of YPS1 Silencing siRNAs
Publisher Journal Name: IJCRT
Your Paper Publication Details:
Published Paper ID: - IJCRT1133055
Register Paper ID - 190418
Title: IN SILICO DESIGNING, VALIDATION AND IN-VITRO SYNTHESIS OF YPS1 SILENCING SIRNAS
Author Name(s): Nipunjot Kaur Soni-Bains
Publisher Journal name: IJCRT
Volume: 2
Issue: 2
Pages: 303-313
Year: June 2014
Downloads: 1830
Abstract
Fission yeast is a useful model for RNA interference because it has single-copy genes for components of the RNAi pathway such as argonaute, dicer and RNA-dependent RNA polymerase (RdRP) (Wood, V. et al., 2002). Schizosaccharomyces pombe has DCR and AGO but not in Saccharomyces cerevisiae (Verdel, A. et al. 2004). Studies till date have proved that RNAi machinery in fission yeast has only epigenetic effects as they help in histone modifications. Present study involved designing of siRNAs against fission yeast protease yps1. Critical design concerns in the selection of siRNA duplexes that are potent and specific.
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The International Journal of Creative Research Thoughts (IJCRT) aims to explore advances in research pertaining to applied, theoretical and experimental Technological studies. The goal is to promote scientific information interchange between researchers, developers, engineers, students, and practitioners working in and around the world.
Indexing In Google Scholar, ResearcherID Thomson Reuters, Mendeley : reference manager, Academia.edu, arXiv.org, Research Gate, CiteSeerX, DocStoc, ISSUU, Scribd, and many more International Journal of Creative Research Thoughts (IJCRT) ISSN: 2320-2882 | Impact Factor: 7.97 | 7.97 impact factor and ISSN Approved. Provide DOI and Hard copy of Certificate. Low Open Access Processing Charges. 1500 INR for Indian author & 55$ for foreign International author. Call For Paper (Volume 13 | Issue 11 | Month- November 2025)
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Last Date :
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Submit Manuscript Online Impact Factor: 7.97 Review Results : Within 02-03 Days Paper Publication : Within 02-03 Days
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
ISSN and 7.97 Impact Factor Details
ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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