Volume 10 | Issue 12

 Abstract

Although proton pump inhibitors (PPI) have a record of remarkable effectiveness and safety in the management of gastroesophageal re?ux disease (GERD), several treatment challenges with PPI have emerged. Dexlansoprazole is the (R)-enantiomer of lansoprazole contained in a formulation that produces two distinct drug releases and significantly increases the duration of active plasma concentrations and percent time pH 4 compared to conventional single-release PPI. In most patients, dexlansoprazole can be taken without regard for meals or meal timing. Dexlansoprazole 60 mg showed comparable efficacy for healing of erosive esophagitis at 8 weeks compared to lansoprazole 30 mg, and dexlansoprazole 30 mg was superior to placebo for maintenance of healed erosive esophagitis at 6 months, with 99 percent of nights and 96 percent of days heartburn-free in patients taking dexlansoprazole 30 mg. The safety pro?le of dexlansoprazole is similar to that of lansoprazole. The extended pharmacodynamic effects, added convenience, and ef?cacy and safety of dexlansoprazole offer a novel approach to gastric pH control in patients with acid-related disorders.

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 Keywords

Mechanism of Action Dexlansoprazole, Pharmacokinetics & Pharmacodynamic, pharmacological properties of dexlansoprazole, Indications for proton pump inhibitors therapy, treatment of gastroesophageal reflux disease.

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Creative Commons Attribution 4.0 and The Open Definition

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Asthi Dhatu, Medo Dhatu, Asthyagni, Dhatvagni, Dhatu, Ushma

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

भारिीय राष्ट्रीय आन्दोलन पुरुष प्रधान था यही कारण है तक भारिीय राष्ट्रीय आन्दोलन पर तलखी गई कई पुस्िकों लेखों आतद में मतहलाओं की सहभातगिा और उनके योगदान को उतिि स्थान नहीं तमला। ित्कालीन तपिसृ त्तात्मक समाज में मतहलाओं की दतुनया घर की िहारदीवारी के भीिर सीतमि थी और उसे पुरुष की अनुगातमनी ही माना जािा था तिर भी राष्ट्रीय आन्दोलन का इतिहास िमाम ऐसी मतहलाओं के साहस, त्याग व बतलदान से भरा है, तजन्होंने अपनी पाररवाररक भूतमका के साथ-साथ राष्ट्रवादी गतितवतधयों में भी महत्वपूणण भूतमका तनभाई थी अनेक मतहलाओं ने अपनी वीरिा, साहस और नेित्ृव क्षमिा का पररिय देिे हुए भारि की स्विंत्रिा के तलये पुरुषों के साथ कंधे से कंधा तमलाकर संघषण तकया। जैसे- वीरांगना लाजो देवी, उदा देवी, अजीजन बाई, ननीवाला देवी, मणृ ातलनी देवी, सनुीति देवी, आजाद तहन्द िौज की जाससू नीरा आयण आतद। क्ांतिकाररयों के कायण में प्रत्यक्ष रूप से महत्वपूणण सहयोग देने वाली सशुीला देवी, प्रकाशविी, लीलानाग, इदं मुिी तसहं , सहुातसनी गांगुली, सातवत्री देवी एवं ऐमू बाई जैसे सैकड़ों नामों से लेकर उजली तमसालों की यह परम्परा अप्रत्यक्ष सहयोग के हजारो लाखों नामों िक िै ली है। प्रस्िुि शोध पत्र में ऐसी ही अज्ञाि वीरांगनाओं का अध्ययन तकया गया है।

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क्ांतिकारी, वीरांगना, राष्ट्रीय आन्दोलन, अमिृ महोत्सव, आजादी, बतलदान, नेित्ृव संघषण।

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Male dominated society, agony, feminine sensibility, discrimination, identity.

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Creative Commons Attribution 4.0 and The Open Definition

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?????? ????????????, ?????? ??????, ?????? ???(?????), ??????????

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Service providers must upgrade their operations support system (OSS) and business support system as the telecommunications industry changes and new technologies like LTE, LTE-A, and 5G networks gain popularity. The performance of an organization's needs for service delivery, fulfillment, and business information depends heavily on OSS and BSS. The setting up of a solution (hardware or software) is known as configuration. Any solution will need to be configured to some extent before being used, which in our reality involves installing operating systems and databases. System integration should assist communication service providers in cutting costs on their OSS/BSS system while also enhancing the overall service delivery and the quality of the client experience

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 Keywords

OSS/BSS, Mediation, Billing, Accounting, Tariff Plan, Product Catalogue

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Socio-economic status, teaching profession, and secondary school teachers

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The term pregnancy, also known as Gestation refers to the period of development of an embryo/fetus within the female reproductive system. Development is a continuous process, beginning with the formation of a zygote. During the nine months of pregnancy, the body undergoes various anatomical changes which after the delivery of baby, normalizes within certain period of time. The changes are seen in the pelvis region, which protects and supports the pelvic contents, provides muscle and ligament attachment and facilitates the transfer of weight from the trunk to the legs in standing, and to the ischial tuberosities in sitting. Postural Changes During the pregnancy process, the overall equilibrium of the spine and pelvis alters. These changes persist up to 8 weeks after delivery. The significant conditions occurring during pregnancy which lead to harm situation to the mother, as well as the baby, are Obesity, Anemia, Hypertension and Thyroid Disorder

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Obesity, Anemia, Hypertension and Thyroid Disorder

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The problem of traffic and teen gang violence and has the goal to control traffic and violence elimination. As there is a constant increase in the number of road users, a perceptive control of traffic will become a very significant issue in the future. In our project, we propose a general definition of robustness and develop methodology using LEDs of standard colours (Red, Yellow and Green) following a universal colour code, Ultrasonic transducers (which is used for measuring distances based on transmitting and receiving ultrasonic signals), Buzzer (which gives an audio signal) and Arduino (which is used for controlling all these components). So, there is a sensor placed at the right side of the road which will detect the object. The sensor will be activated when there is a red signal and will be deactivated when there is a green signal. When detected in the sensor, a buzzer sound will alert the drivers to get back from the zebra crossing. Thus, this system can be implemented in city traffic.

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Traffic control, Vehicle Detection, Arduino, Ultrasonic sensor.

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 Abstract

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Liberation, Patriarchal domination, Gender Sensitization, Injustice.

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Banking is treated as blood for common man in daily activities to do trade and lead modern lifestyle in India now. Nowadays, banking sector acts as the backbone of modern business. Development of any country mainly depends upon the banking system. A bank is a financial institution which deals with deposits and advances and other related services. It receives money from those who want to save in the form of deposits and it lends money to those who need it. The banking is one of the most essential and important parts of the human life. In current faster lifestyle peoples may not do proper transitions without developing the proper bank network. The banking System in India is dominated by nationalized banks. The performance of the banking sector is more closely linked to the economy than perhaps that of any other sector. The growth of the Indian economy is estimated to have slowed down significantly.

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Performance, Transactions, Operations, Automation

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Visual Cryptography is one of the technics to convert secret information into an unreadable format and is used to break private visual data into numbers of shares and is easily maintainable at different locations. However, any person never accesses the original data unless all shares are available. The main objective of this paper is to ensure control of bogus ration cards, minimize the leakage of food grains and avail flexible and secure rationing systems. In this paper, a new Smart Ration Card technique has been proposed, which is based on a dual authentication mechanism that also fulfils the security of biometric data and maintains individual information.

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Visual Cryptography, Steganography, Secure, Biometric Security.

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Keywords: Food System Innovations, Food Security, PMGKY scheme

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Values are a kind of standard principles that are used to judge the worth of an idea or action. They provide the criteria by which we decide whether something is good or bad, right or wrong. Values are taught by the school. Value-based education lays emphasis on overall personality development of individuals in order to shape their future and tackle difficult situations with ease. It moulds the children so they get attuned to changing scenarios while handling their social, moral, emotional and democratic duties efficiently. Value education had taught basic qualities of life like honesty, hard work, brotherhood, culture, socialization, respect for others, kindness, cooperation, compassion, and forgiveness. It has brought the overall personal changes in personal behaviour of students.

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Value Education, Personality Development, Honesty, Kindness,

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

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Grade System, Evaluation, Cumulative Grade Point Average

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Profitability and liquidity, Automobile Industry and Short term investments

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Creative Commons Attribution 4.0 and The Open Definition

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An era of SARS?COVID?19 outbreak with a high contagious percentage around the globe has been the subject of multi?agency research aimed at generating vaccines for active immunization. Scientists across the world are joining hands for advanced tie?ups between medical start?ups and pharmaceutical industries for devices and vaccines development to hinder the progress of this outbreak. The novel coronavirus, SARS-CoV-2, which causes COVID-19, has resulted in a pandemic with millions of deaths. To eradicate SARS-CoV-2 and prevent further infections, many vaccine candidates have been developed. These vaccines include not only traditional subunit vaccines and attenuated or inactivated viral vaccines but also nucleic acid and viral vector vaccines. In contrast to the diversity in the platform technology, the delivery of vaccines is limited to intramuscular vaccination. Although intramuscular vaccination is safe and effective, mucosal vaccination could improve the local immune responses that block the spread of pathogens.

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Covid19,Vaccine,Efficacy,ADR, Immune Response, Acceptance, Hesitation, and Rejection

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The Acute and Chronic effects of Medication Remdesivir, sold under the brand name Veklury and developed by Gilead Sciences, are discussed in the Review. This anti- viral medication was given to the victims of the Pandemic Disease- Covid-19. Molar mass: 602.585 g/mol ChEMBL Id: 4065616 ChemSpider ID: 58827832 Formula: C27H35N6O8P Pronunciation: /r?m?d?s?v??r/ rem-DESS-i- veer Other names: GS-5734 AHFS/Drugs.com: Monograph This Drug helped the patients overcome the illness but had grave after- shocks as stated and explained below.

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: Remdesivir, Chronic, Acute, Kidney, Liver.

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Creative Commons Attribution 4.0 and The Open Definition

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Evaluation, Assessment, Teachers, Students, Innovative Methods, Level of understanding.

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Creative Commons Attribution 4.0 and The Open Definition

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ABSTRACT Wet granulation, direct compression, or dispersion of solid particles within solid particles within a porous matrix created by employing various polymers, such as polymethyl methacrylate (PMMA), polyglycolic acid, HPMC, etc., are the main methods used to create sustained release matrix tablets. The matrix regulates the drug's rate of release. Release inhibitors, such as HPMC, can help with sustained release, making them a key excipient in the formulation. The process involves directly compressing a mixture of the medicine, the retardant material, and the additives to create a tablet with the drug embedded in the matrix core of the retardant. Granulation may also be done before compression. The matrices employed could be mineral, hydrophilic, hydrophobic, or biodegradable in nature.Studies of in-vitro dissolution can be used to determine the medication release rate. Ambroxol HCl, nateglinide, and other medications have been created as sustained release matrix tablets. Thus, by reducing the total dose and dosage schedule, sustained release matrix tablets can provide improved patient compliance, which is very beneficial for the treatment of chronic diseases.

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KEYWORDS: Sustained release, in-vitro dissolution,Polymer, Matrix tablet.

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Creative Commons Attribution 4.0 and The Open Definition