Volume 9 | Issue 11

 Abstract

ABSTRACT: A simple, sensitive and high performance liquid chromatographic method was developed for the estimation of anti-diabetic drugs Metformin Hydrochloride (MET) and Teneligliptin (TEN) in pure and in pharmaceutical dosage forms. A Gemini C18 column (150x4.6mm, 5?) was used with a mobile phase contain a mixture of Ammonium Acetate Buffer (pH-3) and Acetonitrile taking ratio of 42: 58. Set the flow rate was 0.3ml/min and effluents were monitored at 255nm and eluted at 5.18min (MET) and 8.1min (TEN). Calibration curve was plotted within range from 0.5-51 ?g/ml for MET and 0.3-31 ?g/ml for TEN. This assay was validated for the parameters i.e. accuracy, precision, robustness and all system suitability parameter. The method can be useful routine analysis for the determination on metformin and teneligliptin in pharmaceutical dosage forms.

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KEYWORDS: - Metformin hydrochloride, Teneligliptin, HPLC, Pharmaceutical dosage forms.

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The knowledge of the inter-relationship between periodontal tissues and restoration is a predominant to ensure relevant form, function, esthetics and comfort of the dentition. Most of us as a dentist are ignorant of this important relationship, hence uncertainty remains regarding a special concept that is biologic width, its maintenance and applications of crown lengthening in cases of biologic width violation. A Crown lengthening procedure is a constitutive component of the esthetic armamentarium and is utilized with increasing frequency to inflate the appearance and retention of restorations placed within the esthetic zone. Thus, we are presenting a case report on management of biological width with gingivo-osseous surgery.

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biological width, crown lengthening, periodontal health, anterior restoration, esthetic restoration

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Background: Thyroid cancer is the most common endocrine cancer with an increasing incidence in the world. Immunohistochemistry is widely used to differentiate benign and malignant lesions in thyroid cancer through the identification of molecular markers. In this study, we aimed to examine the association between matrix metalloproteinase-9 (MMP-9) expression and its relationship with the clinical stage of PTC patients. Methods: We recruited 26 patients with PTC in Dr. Soetomo General Hospital (Surabaya, Indonesia) in between September 2020-Agustus 2021. MMP-9 expression was examined using immunohistochemistry. Clinical staging was determined using 8th American Joint Committee on Cancer (AJCC) guideline. Results: The number of females was higher than males (73.1% and 26.9%, respectively). There was no significant association between clinical stage and MMP-9 expression (P = 0.16). The results of the analysis also showed that there were no statistically significant association between T, N, and M with MMP-9 expression (P > 0.05 for all). Conclusion: There was no significant association between MMP-9 expression and clinical staging of papillary thyroid carcinoma. Keyword: Matrix metalloproteinase-9, clinical staging, papillary thyroid carcinoma, TNM system

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Matrix metalloproteinase-9, clinical staging, papillary thyroid carcinoma, TNM system

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Imagination is the only thing where you can wander without limitations. It is a pleasure which can be tasted by every individual. A poor man in China can visit Disney land in America through his imagination. It makes impossible things possible. S.T. Coleridge is the poet who is well known for his imagery. Kubla khan is one of his famous poem where he poured his imagination of thoughts in words. Coleridge makes his reader to smell the entire fragrance of imagination through his poem. This is the poem of his dream and it has abrupt ending. This poem happens in the place called Xanadu which was ruled by a Mangolian emperor Kubla Khan. He orders his servants to build a massive dome building and the poem continues with lots of beautiful sceneries.

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Imagination, Hermeneutics, Reader's response theory

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Newborn resuscitation is a complex procedure that requires the use of specialized knowledge and skills in an emotionally charged and stressful situation. Knowledge about newborn resuscitation, frequent performance of skills and comfort level with skill performance is dimensions of quality implementation of newborn resuscitation. Newborn resuscitation is a series of action that are taken in order to revive an infant immediately after birth so that normal respiration and circulation may be initiated and maintained. It is an attempt to facilitate the dynamic transition from fetal to neonatal physiology. The approach used for this study was non experimental study research approach. The research variable of the study is knowledge and practice regarding resuscitation of Newborn among staff nurses working in neonatal intensive care unit and extraneous variable are age, gender education qualification, area of residence, marital status, professional experience and source of information. The pilot study was conducted to find the feasibility of the study 23nd of February 2021 to 28th of February 2021 among Staff nurses. The main study was conducted from 21-04- 2021 to 30-04-2021 among 60 subjects; the subject was selected by convenient sampling technique and data was analysed and interpreted using descriptive and inferential statistics. The overall knowledge on resuscitation of Newborn. The mean score is 19.16 with a mean percentage of 59.87 with a standard deviation of 1.719, practice scores of staff nurses on resuscitation of Newborn were found to be 73.7% with standard deviation 1.91. The present study was to assess the knowledge and practice regarding resuscitation of Newborn among staff nurses working in neonatal intensive care unit had moderate knowledge and moderately Good Practice on resuscitation of Newborn.

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knowledge and practice, resuscitation, newborn

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, Entertainment , Indian Cinema Bio-Pic, Enlightenment

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A STUDY TO ASSESS THE KNOWLEDGE REGARDING HYSTERECTOMY AMONG WOMEN ATTENDING MCH CENTER, AT TIRUPATI. Objectives: ? To assess the level of knowledge among women regarding hysterectomy. ? To find out the association between knowledge scores of women regarding hysterectomy with their selected socio-demographic variables. Methodology: The research approach used for the present study was Cross-Sectional Descriptive Research Design. The sample of the study were chosen by Non-Probability Convenient Sampling Technique, which includes 100 Women aged between 35-60 years who were attending MCH center at Tirupati. A structured questionnaire was used to collect the data which consists of 25 dichotomous questions. Results: The study findings revealed that, 61% had moderate knowledge, 23% had adequate knowledge and 16% had inadequate knowledge and a significant association between age of women (x2= 38.311, P=0.001), marital status (x2=18.449, P=0.001), education of the women (x2 =26.400, P=0.001), occupation (x2= 21.019, P=0.002) living area (x2= 20.572, P=0.002), type of family (x2=13.798,P=0.008), family history of hysterectomy(x2=9.509,P=0.009), were significant at p <0.01 level. The relationship between family income of the women (x2=10.041, P=0.040), was significant at <0.05 level. Conclusion: The conclusion suggests that, majority of women had moderate knowledge on hysterectomy and hence women need to improve the knowledge regarding hysterectomy.

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Knowledge, Hysterectomy.

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Oral health, dental attrition, tooth wear, public health

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Key words: Indigenous, Sports, Interest, Participation, Enjoy, School, Children etc.

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Strict lockdown imposed in India form 24th March 2020 to 31st May 2020 to curb the spread of corona virus epidemic has had a serious impact on various sectors except the area of ??essential services. Self-employed and informal workers, who do not have social security nets, are most affected by the lockdown. The lockdown has also had a major impact on rural areas. Farmers are suffering due to disruption of supply chain. A large part of the population depends on the agricultural sector and thus it is important to understand the impact of the epidemic on the agricultural sector.

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Image super resolution, Efficient Sub-Pixel Convolutional Neural Network, Bi-cubic Interpolation , Bi-Linear Interpolation , Single Image Super Resolution

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The recent geological findings and scientific research aimed at validating the identity of Sarasvati has rather encouraged ancient Indian scholars to probe into the literary sources to explore the possibilities that in any means could establish the identity of Sarasvati as a river. The occurrence of the term Sarasvati in ancient Indian texts has provided the impetus to the research for it has been augmented with the latest scientific findings. Still, Sarasvati struggles to establish its identity as a river wherefore her identity as a goddess has predominantly been established. The paper is an attempt to explore the identity of the Sarasvati citing references from the ancient Indian texts.

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Sarasvati River, Ancient Indian Rivers, Rigvedic Rivers, Ancient Indian History

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BHARAT ME BAUDDH DARSHAN

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BHARAT ME BAUDDH DARSHAN

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Blood parameters play an important role in the health of an individual. The blood parameters such as sugar level, Hemoglobin and triglycerides have its effect on the health of an individual. 315 teachers working in various schools and college of Meerut district participated voluntarily in this study. The results of the study showed that the mean of Hemoglobin in male teachers having age below 35 years is 14.79%, where as their female counterparts are having 11.51%. at the same time the male and female teachers of below 60 years of age where having 13.9 and 11.4 % respectively. The overall random Blood sugar level of teachers of all age was recorded 103.02. 4% of the teachers are having diabetes and 5% of teachers are in pre diabetic stage. The triglycerides level of the teachers was also tested, and it was seen that 30% of male and 54% of female teachers were having normal level whereas 1% males and 3% females were having high level of Triglyceride. The result of the study reveals that the fitness level of the teachers is not in good state. The non active lifestyle is affecting their health level. Therefore, it is suggested that regular cardio workout is very much needed and at the same time well-disciplined food habits must be adopted. The regular exercises such as running, cycling, yoga etc. can only save us from such diseases.

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Hemoglobin, Triglycerides and Teacher

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"BHOPAL JILE KI KRASHI VIKAS ME MADHYAPRADESH RAJY SAHAKARI VIPANAN SANGH

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"BHOPAL JILE KI KRASHI VIKAS ME MADHYAPRADESH RAJY SAHAKARI VIPANAN SANGH

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BACKGROUND AND PURPOSE: High blood pressure ranging from 140-159 mm Hg of SBP and/or 90-99 mmHg of DBP is defined as Stage 1 hypertension. Various lifestyle modification can help to control BP in addition to drugs therapy such as aerobic exercises etc. Interval aerobic exercises has shown benefits for reducing BP. There is lack of evidences that compare the effects of Moderate intensity interval training (MIIT) and low intensity continuous training in combination with yoga (LICT+YOGA) on BP in hypertensive patients. METHODOLOGY: 40 stage 1 hypertensive patients of 45-55 years of age were recruited and divided into two group. Group-A (n=20) and Group-B (n=20) received MIIT and LICT+YOGA for 4 sessions lasting 50-60 minutes; for 4 weeks duration respectively. MIIT at work: rest ratio of 3:1 and LICT+YOGA at 11 RPE (30 min) + Surya namaskar (10 min) with warm up and cool down exercises. Weight, HR, SBP, DBP and 6 MWD (for functional capacity) were taken before and after treatment. RESULT: MIIT and LICT+YOGA, both groups showed statistically significant improvements with P=0.00. MIIT was superior in reducing HR, SBP, DBP and increasing 6 MWD than LICT+YOGA with P<0.05 except in weight reduction with P=0.58. Statistical analysis was done using SPSS v. 23 and Excel 2019 for paired and unpaired T tests. CONCLUSION: Both interventions can elicit benefits on hypertension by reducing BP, HR, weight and improve functional capacity. Thus, it can inhibit drug dosage and its adverse effects by addition BP reduction. MIIT was found greater for hypertensive patients to reduce BP than LICT+YOGA.

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Moderate Intensity Interval Training, Low Intensity Continuous Training, Surya Namaskar, BP, Stage 1 Hypertension.

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Sentimental analysis

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Aa sansodhan abhyas no hetu shaheri ane gramin Vidyarthiona hath tatha khabhana snayubal ane petna snayibalno abhyas krvano hto. Aa sanshodhan abhyasma sharirik shikshan ane ramat vigyan vidyashakha, Sadarama B.P.E.S na dritya varshma abhyas krta 17 thi 21 varshni umar dhravta 15 shaheri ane 15 gramin Vidyarthi bhaione yadachchh paddhatithi vishaypatro tarike pasand karvama aavya hta. Mapanna dhoranoma hath tatha khabhana snayubalnu mapan uchak kasoti ane petna snayubalnu mapan saynotthan kasoti dvara karvama aavyu htu. Prapt karel mahiti par 't' test lagu padi hti. Banne juth hath tatha khabhana snayubal ma samanta dharavta hta. Shaheri juth karta gramin juth petna snayubalma chadhiyatu jova maliyu htu.

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Shaheri Ane Gramin Vidyarthio, Uchak Kasoti, Saynotthan Kasoti, 't' test

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Nagaland is a state inhabited by 16 hospitable tribes and other sub-tribes. Nagas are the tribal people, belong to Mongoloid ethnic group. Nagas lived a life, centered on agriculture and headhunting. Each tribe is distinctively different from the other in terms of tradition, customary practices, language and attires are preserved. The word culture has varied meanings and it is inseparable from human life. According to Oxford Dictionary, Culture is defined as the arts and other manifestation of human intellectual achievements of a particular time or people. Naga Culture is associated with the ways of living and therefore it can mean the way they eat, the way they dress, the way they speak or the way they work to earn their livelihoods. It includes the norms, customs, traditions and beliefs that are related with the mountain dwelling people i.e. the Naga community. Culture is the common heritage of the society and passed on from one generation to the next. The modern ignition of information and new desires should not break up the Structure of the Naga society but it should protect its culture. The history and traditions of the Nagas are preserved in the memories of the people and handed down to generation to generation. It includes everything under the sun that can be communicated to the next generation. It is both specific and conceptual that is expressed in tangible objects as well as in ideas and philosophy. The rich heritage is the patrimony and it speaks volumes about its culture and customs of the tribe. It has been decaying because of the modernization .This paper aims, to preserve and promote the rich cultural heritage of the Nagas while they are still relatively intact.

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Naga, Culture, Preservation, Heritage, Tribes, Tradition

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