IJCRT Peer-Reviewed (Refereed) Journal as Per New UGC Rules.
ISSN Approved Journal No: 2320-2882 | Impact factor: 7.97 | ESTD Year: 2013
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 7.97 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(CrossRef DOI)
| IJCRT Journal front page | IJCRT Journal Back Page |
Paper Title: AN INVESTIGATION OF YOUTH PROBLEMS AMONG MALE AND FEMALE ADOLESCENTS
Author Name(s): Dr. Nagorao Manikrao Palwade
Published Paper ID: - IJCRT2608211
Register Paper ID - 312617
Publisher Journal Name: IJPUBLICATION, IJCRT
DOI Member ID: 10.6084/m9.doi.one.IJCRT2608211 and DOI :
Author Country : Indian Author, India, 431401 , Parbhani, 431401 , | Research Area: Medical Science All Published Paper URL: http://ijcrt.org/viewfull.php?&p_id=IJCRT2608211 Published Paper PDF: download.php?file=IJCRT2608211 Published Paper PDF: http://www.ijcrt.org/papers/IJCRT2608211.pdf
Title: AN INVESTIGATION OF YOUTH PROBLEMS AMONG MALE AND FEMALE ADOLESCENTS
DOI (Digital Object Identifier) :
Pubished in Volume: 14 | Issue: 8 | Year: August 2026
Publisher Name : IJCRT | www.ijcrt.org | ISSN : 2320-2882
Subject Area: Medical Science All
Author type: Indian Author
Pubished in Volume: 14
Issue: 8
Pages: b898-b903
Year: August 2026
Downloads: 35
E-ISSN Number: 2320-2882
The present study was conducted to examine gender differences in youth problems among adolescents in Parbhani, Maharashtra. A total of 200 adolescents were selected through random sampling from the population of Parbhani, Maharashtra. The sample consisted of 100 male adolescents and 100 female adolescents. Efforts were made to obtain a representative sample with respect to area of residence and educational background, while participants were selected from a broadly similar socioeconomic background. Youth problems were assessed using the Youth Problem Inventory developed by Dr. (Mrs.) M. Verma. The mean score obtained by male adolescents was 67.56 with a standard deviation of 8.72, whereas female adolescents obtained a mean score of 58.29 with a standard deviation of 7.63. An independent-samples t test was used to examine the difference between the two groups. The obtained t value was 8.00 with 198 degrees of freedom, which was statistically significant at the .001 level. The findings indicate that male adolescents reported significantly higher levels of youth problems than female adolescents. The findings are consistent with previous Indian research reporting significant gender differences in adolescent problems and emphasizing the importance of gender-sensitive approaches to understanding and addressing youth concerns. The study highlights the need for systematic identification, counselling, and preventive interventions for adolescents experiencing family, educational, social, and personal difficulties.
Licence: creative commons attribution 4.0
Youth Problems, Adolescents, Gender Differences.
Paper Title: Some properties of Left Bi-quasi Ideals in Ternary Semirings
Author Name(s): Dr.Thiriveedi Sunitha
Published Paper ID: - IJCRT2608210
Register Paper ID - 312612
Publisher Journal Name: IJPUBLICATION, IJCRT
DOI Member ID: 10.6084/m9.doi.one.IJCRT2608210 and DOI : https://doi.org/10.56975/ijcrt.v14i8.312612
Author Country : Indian Author, India, 518002 , Kurnool, 518002 , | Research Area: Mathematics All Published Paper URL: http://ijcrt.org/viewfull.php?&p_id=IJCRT2608210 Published Paper PDF: download.php?file=IJCRT2608210 Published Paper PDF: http://www.ijcrt.org/papers/IJCRT2608210.pdf
Title: SOME PROPERTIES OF LEFT BI-QUASI IDEALS IN TERNARY SEMIRINGS
DOI (Digital Object Identifier) : https://doi.org/10.56975/ijcrt.v14i8.312612
Pubished in Volume: 14 | Issue: 8 | Year: August 2026
Publisher Name : IJCRT | www.ijcrt.org | ISSN : 2320-2882
Subject Area: Mathematics All
Author type: Indian Author
Pubished in Volume: 14
Issue: 8
Pages: b892-b897
Year: August 2026
Downloads: 54
E-ISSN Number: 2320-2882
Algebraic structures play a very outstanding role in mathematics. Iseki introduced the concept of quasi ideal for a semirings. The quasi ideals in ternary semirings are a generalization of left and right ideals. Bi-ideals are generalization of quasi ideals. In 2017, Marapureddy Murali Krishna Rao introduced bi-quasi ideals in semirings. With this connection, here we are introducing some properties of bi-quasi ideals in ternary semirings.We proved that every left(right) ideal of ternary semiring is bi-quasi ideal, every quasi ideal of ternary semiring is bi-quasi ideal and every bi-ideal of ternary semiring is a bi-quasi ideal.
Licence: creative commons attribution 4.0
Ternary semiring, ideal,bi-ideal,bi-quasi ideal
Paper Title: Excess Salt - The Killer & Homoeopathy
Author Name(s): Dr. Tridibesh Tripathy, Prof. Rakesh Dwivedi, Ms. Sanskriti Tripathy
Published Paper ID: - IJCRT2608209
Register Paper ID - 312609
Publisher Journal Name: IJPUBLICATION, IJCRT
DOI Member ID: 10.6084/m9.doi.one.IJCRT2608209 and DOI :
Author Country : Indian Author, India, - , -, - , | Research Area: Health Science All Published Paper URL: http://ijcrt.org/viewfull.php?&p_id=IJCRT2608209 Published Paper PDF: download.php?file=IJCRT2608209 Published Paper PDF: http://www.ijcrt.org/papers/IJCRT2608209.pdf
Title: EXCESS SALT - THE KILLER & HOMOEOPATHY
DOI (Digital Object Identifier) :
Pubished in Volume: 14 | Issue: 8 | Year: August 2026
Publisher Name : IJCRT | www.ijcrt.org | ISSN : 2320-2882
Subject Area: Health Science All
Author type: Indian Author
Pubished in Volume: 14
Issue: 8
Pages: b887-b891
Year: August 2026
Downloads: 37
E-ISSN Number: 2320-2882
It is an irony that Salt is an integral part of homoeopathic therapeutics as the contribution of salt is huge in the preparation of homoeopathic medicines. Numbers of medicines are prepared from the salt in homoeopathy as per the Homoeopathic Pharmacopoeias of various nations. 'Natrum Mur' is a leading drug in Homoeopathy & that is Sodium Chloride. On the other hand, there are also a numbers of medicines to treat conditions arising from excessive intake of salt. The current article discusses the intake of excess salt & its consequences in the human body. Thereafter, it delves in to the epidemiology of the consequences of consuming extra salt, its clinical repercussions and management of these issues & finally the application of homoeopathy to deal with this issue. It concludes with the cost effectiveness & therapeutic effectiveness of the homoeopathic system of medicine & suggests its involvement on a large scale in the nation. It only reinforces the age old concept of managing these chronic conditions through diet, regimen, exercise & homoeopathy. The suggestion of large scale use of homoeopathy is based on the premise of the modalities of essential medicines. The National List of Essential Medicines (NLEM) envisages that a medicine can be called essential only if it is cost effective, clinically effective & has no side effects. Homoeopathy fits into this triad fully. The article also suggests a treatment protocol based on the typical clinical features of excessive salt consumption & aspires that the public benefits from the protocol at large.
Licence: creative commons attribution 4.0
Hypertension, Stroke, Homoeopathy, Miasms, TIA
Paper Title: BEHAVIOUR OF JUTE FIBRE REINFORCED CONCRETE WITH JUTE FIBRE REINFORCED POLYMER (JFRP) BARS AS A PARTIAL REPLACEMENT FOR STEEL REINFORCEMENT
Author Name(s): Kandru Suresh
Published Paper ID: - IJCRT2608208
Register Paper ID - 312620
Publisher Journal Name: IJPUBLICATION, IJCRT
DOI Member ID: 10.6084/m9.doi.one.IJCRT2608208 and DOI :
Author Country : Indian Author, India, 500088 , Hyderabad, 500088 , | Research Area: Science and Technology Published Paper URL: http://ijcrt.org/viewfull.php?&p_id=IJCRT2608208 Published Paper PDF: download.php?file=IJCRT2608208 Published Paper PDF: http://www.ijcrt.org/papers/IJCRT2608208.pdf
Title: BEHAVIOUR OF JUTE FIBRE REINFORCED CONCRETE WITH JUTE FIBRE REINFORCED POLYMER (JFRP) BARS AS A PARTIAL REPLACEMENT FOR STEEL REINFORCEMENT
DOI (Digital Object Identifier) :
Pubished in Volume: 14 | Issue: 8 | Year: August 2026
Publisher Name : IJCRT | www.ijcrt.org | ISSN : 2320-2882
Subject Area: Science and Technology
Author type: Indian Author
Pubished in Volume: 14
Issue: 8
Pages: b879-b886
Year: August 2026
Downloads: 40
E-ISSN Number: 2320-2882
: Steel is still the reinforcement of choice in most concrete work, mainly because it is strong and behaves predictably, but rising steel prices and ongoing corrosion problems have pushed researchers to look elsewhere. This study looks at jute, a cheap, renewable fibre that is widely available in India, as a way to cut down on steel use without giving up too much performance. Jute Fibre Reinforced Concrete (JFRC) was prepared with fibre contents of 0.25%, 0.50% and 0.75% by weight, and cube specimens were tested for compressive and split tensile strength at 7, 14 and 28 days to find the fibre content that works best. Jute Fibre Reinforced Polymer (JFRP) bars, made from treated jute fibre, binding wire and an epoxy resin coating, were then cast into beam specimens as a partial substitute for conventional steel bars, and their flexural behaviour was compared against beams reinforced entirely with steel. Across every age tested, 0.50% jute fibre gave the best compressive and split tensile results, with the 28-day compressive strength going up by close to 19% over the plain concrete control, while 0.75% fibre content actually performed worse than the control, most likely because the fibres were not dispersing properly at that dosage. Beams cast with 0.50% jute fibre concrete and 50% steel + 50% JFRP bar reinforcement reached a flexural strength of 17.83 MPa, recovering most of the capacity lost when half the steel was swapped out for jute bars. Overall, the results suggest that jute fibre reinforced concrete combined with JFRP bars is a workable, low-cost way to reduce dependence on steel in reinforced concrete members, though the trade-off in stiffness and long-term durability still needs closer study before it can be used in structural applications.
Licence: creative commons attribution 4.0
- Jute fibre, JFRP bars, natural fibre reinforced concrete, compressive strength, split tensile strength, flexural strength, sustainable construction.
Paper Title: Inclusive Pedagogy In Indian Knowledge Systems: Insights From Special Education Classrooms
Author Name(s): Darshita Shah
Published Paper ID: - IJCRT2608207
Register Paper ID - 312608
Publisher Journal Name: IJPUBLICATION, IJCRT
DOI Member ID: 10.6084/m9.doi.one.IJCRT2608207 and DOI :
Author Country : Indian Author, India, 390024 , Vadodara, 390024 , | Research Area: Social Science All Published Paper URL: http://ijcrt.org/viewfull.php?&p_id=IJCRT2608207 Published Paper PDF: download.php?file=IJCRT2608207 Published Paper PDF: http://www.ijcrt.org/papers/IJCRT2608207.pdf
Title: INCLUSIVE PEDAGOGY IN INDIAN KNOWLEDGE SYSTEMS: INSIGHTS FROM SPECIAL EDUCATION CLASSROOMS
DOI (Digital Object Identifier) :
Pubished in Volume: 14 | Issue: 8 | Year: August 2026
Publisher Name : IJCRT | www.ijcrt.org | ISSN : 2320-2882
Subject Area: Social Science All
Author type: Indian Author
Pubished in Volume: 14
Issue: 8
Pages: b871-b878
Year: August 2026
Downloads: 47
E-ISSN Number: 2320-2882
Inclusive education in India is frequently addressed through policy directives, yet there is limited empirical research on pedagogical practices that facilitate inclusion in everyday classroom settings (Rakshit & Yadav, 2025). This study examines inclusive pedagogical practices in special education classrooms through the lens of Indian Knowledge Systems (IKS). Utilizing a qualitative research method, the research focuses on three classrooms and six teachers within a special education context in Vadodara, Gujarat. The classrooms and teachers were selected through purposive sampling according to criteria such as experience in special education and familiarity with inclusive teaching practices, ensuring a comprehensive understanding of how these methods are applied. Data from classroom interaction transcripts and teacher narratives were subjected to thematic analysis, which entailed coding, pattern identification, and theme development to capture the core aspects of inclusive pedagogy. The analysis shows that inclusive pedagogy is enacted through individualized instruction, experiential and multi-sensory learning, relational care, peer-supported interaction, and adaptable assessment strategies. These methods emphasize learner readiness, participation, and emotional well-being over standardized academic outcomes. When interpreted through the IKS framework, the findings align substantially with indigenous pedagogical principles, such as learner readiness (adhik?ra), experiential learning (anubhava and abhy?sa), and ethical commitment in the teacher-learner relationship. This study delivers empirical evidence to the discussion of inclusive education by demonstrating how Indian Knowledge Systems can inform a culturally rooted, practice-oriented model of inclusive pedagogy.
Licence: creative commons attribution 4.0
Inclusive pedagogy, Indian Knowledge Systems, Special education, Classroom practices, NEP 2020
Paper Title: Alert Prioritization in Security Operations Centre Using an Intelligent System to Reduce Alert Fatigue and Enhance Threat Monitoring
Author Name(s): Hemant Chaudhari, Deepika Ajalkar, Atharv Amrutkar, Mahesh Katare
Published Paper ID: - IJCRT2608206
Register Paper ID - 308765
Publisher Journal Name: IJPUBLICATION, IJCRT
DOI Member ID: 10.6084/m9.doi.one.IJCRT2608206 and DOI :
Author Country : Indian Author, India, 412207 , Pune, 412207 , | Research Area: Science and Technology Published Paper URL: http://ijcrt.org/viewfull.php?&p_id=IJCRT2608206 Published Paper PDF: download.php?file=IJCRT2608206 Published Paper PDF: http://www.ijcrt.org/papers/IJCRT2608206.pdf
Title: ALERT PRIORITIZATION IN SECURITY OPERATIONS CENTRE USING AN INTELLIGENT SYSTEM TO REDUCE ALERT FATIGUE AND ENHANCE THREAT MONITORING
DOI (Digital Object Identifier) :
Pubished in Volume: 14 | Issue: 8 | Year: August 2026
Publisher Name : IJCRT | www.ijcrt.org | ISSN : 2320-2882
Subject Area: Science and Technology
Author type: Indian Author
Pubished in Volume: 14
Issue: 8
Pages: b865-b870
Year: August 2026
Downloads: 127
E-ISSN Number: 2320-2882
Security Operations Centers (SOCs) today face an overwhelming number of security alerts due to the rapid growth of cyber threats and widespread use of monitoring tools. While these alerts play a crucial role in identifying potential attacks, many of them turn out to be false positives or low-risk events. This often leads to alert fatigue, making it difficult for analysts to focus on real threats and respond efficiently. To address this issue, this project proposes an AI/ML-based alert prioritization system that intelligently filters and ranks security alerts from multiple sources such as SIEM systems, intrusion detection systems, firewalls, and endpoint security tools. The system processes alerts through stages like preprocessing, feature extraction, and supervised machine learning classification to identify high-risk incidents. A centralized dashboard displays prioritized alerts along with risk scores, helping analysts make faster and better decisions. By reducing unnecessary alert noise and improving visibility, the system enhances SOC performance, minimizes response time, and supports proactive threat detection in a secure and controlled environment.
Licence: creative commons attribution 4.0
Security Operations Center, Alert Prioritization, Artificial Intelligence, Machine Learning, SIEM, Cybersecurity Automation.
Paper Title: Air Pollution and Health in a Changing Climate: A Comprehensive Review of Exposure, Disease Burden, and Policy Response
Author Name(s): ANGITA, Vinit Kumar, Ekta Panday, Satish Gautam
Published Paper ID: - IJCRT2608205
Register Paper ID - 312615
Publisher Journal Name: IJPUBLICATION, IJCRT
DOI Member ID: 10.6084/m9.doi.one.IJCRT2608205 and DOI :
Author Country : Indian Author, India, 284128 , Jhansi, 284128 , | Research Area: Science and Technology Published Paper URL: http://ijcrt.org/viewfull.php?&p_id=IJCRT2608205 Published Paper PDF: download.php?file=IJCRT2608205 Published Paper PDF: http://www.ijcrt.org/papers/IJCRT2608205.pdf
Title: AIR POLLUTION AND HEALTH IN A CHANGING CLIMATE: A COMPREHENSIVE REVIEW OF EXPOSURE, DISEASE BURDEN, AND POLICY RESPONSE
DOI (Digital Object Identifier) :
Pubished in Volume: 14 | Issue: 8 | Year: August 2026
Publisher Name : IJCRT | www.ijcrt.org | ISSN : 2320-2882
Subject Area: Science and Technology
Author type: Indian Author
Pubished in Volume: 14
Issue: 8
Pages: b852-b864
Year: August 2026
Downloads: 38
E-ISSN Number: 2320-2882
Airborne contaminants and global warming are both of the leading severe and interrelated environmental issues impacting people worldwide in the 21st century. Together, these factors have a significant effect on healthy ecosystems, ecological sustainability, human well-being, and especially impact on vulnerable communities in developed as well as developing nations. Human-caused processes such as burning of fossil fuels, industrial development, urbanization, transport and agricultural methods have resulted in a substantial rise in atmospheric levels of particulate matter (PM2.5 and PM10), nitrogen dioxide (NO2), sulphur dioxide (SO2), ozone (O3), carbon monoxide (CO), volatile organic compounds (VOCs) and black carbon. Around a comparable time, climate change influences weather trends due to higher temperatures, different patterns of rainfall, enhanced atmospheric equilibrium, burning forests, and severe thunderstorms, all of which affect the production, transportation and scattering of harmful substances, and the human inhalation of these substances. This article critically examines the connections among air pollution, global warming, human contact, health effects, and government policies. It covers the main sources of atmospheric pollutants, routes of exposure, biological systems, and the effects of air pollutants on pulmonary, cardiovascular, nervous system, metabolism, reproduction, and psychological health, cancer, and premature death. It also assesses the effect of airborne pollutants on DALYs, YLL and shortfalls in life cycle, along with health disparities in various regions and socioeconomic categories. This article also discusses how global warming can worsen airborne pollutants episodes due to enhanced photochemical ozone synthesis, wildfire emission levels, urban heat island phenomenon, and changes in airflow. The success rate, difficulties with implementation, and potential outcomes of various national and international policy proposals, such as the World Health Organization's (WHO) air quality standards, the UN Sustainable Development Goals (SDGs), Paris Agreement, as well as India's National Clean Air Program (NCAP) were assessed critically. Technological advances including satellite-based remote sensing; cost-effective network sensors, AI, machine learning, and high-level precision health care are introduced as revolutionary instruments for risk assessment and ecological governance. Strengthening multidisciplinary studies, expanding long-term exposure observation, improving surveillance frameworks, and implementing scientifically supported environmental regulations are critical to reducing disease burdens and building adaptability to global warming. A coordinated worldwide approach of atmospheric science, epidemiological research, public health and environmental policies will be required to achieve sustainable progress and protect subsequent generations.
Licence: creative commons attribution 4.0
Keywords: Air pollution, Climate change, Human health burden, particulate matter, Air quality management, Sustainable development, Human health policies
Paper Title: An Intelligent IoT Framework for Battery Health Monitoring and Remaining Useful Life Prediction
Author Name(s): Kamaljeet Kour, Er. Sheetal Gandotra, Dr. Mekhla Sharma
Published Paper ID: - IJCRT2608204
Register Paper ID - 312108
Publisher Journal Name: IJPUBLICATION, IJCRT
DOI Member ID: 10.6084/m9.doi.one.IJCRT2608204 and DOI : https://doi.org/10.56975/ijcrt.v14i8.312108
Author Country : Indian Author, India, 180010 , Jammu, 180010 , | Research Area: Science and Technology Published Paper URL: http://ijcrt.org/viewfull.php?&p_id=IJCRT2608204 Published Paper PDF: download.php?file=IJCRT2608204 Published Paper PDF: http://www.ijcrt.org/papers/IJCRT2608204.pdf
Title: AN INTELLIGENT IOT FRAMEWORK FOR BATTERY HEALTH MONITORING AND REMAINING USEFUL LIFE PREDICTION
DOI (Digital Object Identifier) : https://doi.org/10.56975/ijcrt.v14i8.312108
Pubished in Volume: 14 | Issue: 8 | Year: August 2026
Publisher Name : IJCRT | www.ijcrt.org | ISSN : 2320-2882
Subject Area: Science and Technology
Author type: Indian Author
Pubished in Volume: 14
Issue: 8
Pages: b834-b851
Year: August 2026
Downloads: 86
E-ISSN Number: 2320-2882
Licence: creative commons attribution 4.0
Keywords - Lithium-Ion Battery, State of Health (SOH), Remaining Useful Life (RUL), Attention-BiLSTM, CNN-LSTM, GRU, Deep Learning, Internet of Things (IoT), Battery Management System (BMS), Predictive Maintenance.
Paper Title: The thermodynamic studies of substituted heterocyclic compound in 1, 4 dioxane system in the temperature range 303.15 to 323.15K.
Author Name(s): Yogesh C. Mavle
Published Paper ID: - IJCRT2608203
Register Paper ID - 312552
Publisher Journal Name: IJPUBLICATION, IJCRT
DOI Member ID: 10.6084/m9.doi.one.IJCRT2608203 and DOI :
Author Country : Indian Author, India, 425508 , Raver, 425508 , | Research Area: Chemistry All Published Paper URL: http://ijcrt.org/viewfull.php?&p_id=IJCRT2608203 Published Paper PDF: download.php?file=IJCRT2608203 Published Paper PDF: http://www.ijcrt.org/papers/IJCRT2608203.pdf
Title: THE THERMODYNAMIC STUDIES OF SUBSTITUTED HETEROCYCLIC COMPOUND IN 1, 4 DIOXANE SYSTEM IN THE TEMPERATURE RANGE 303.15 TO 323.15K.
DOI (Digital Object Identifier) :
Pubished in Volume: 14 | Issue: 8 | Year: August 2026
Publisher Name : IJCRT | www.ijcrt.org | ISSN : 2320-2882
Subject Area: Chemistry All
Author type: Indian Author
Pubished in Volume: 14
Issue: 8
Pages: b830-b833
Year: August 2026
Downloads: 44
E-ISSN Number: 2320-2882
Densities, viscosities of some substituted heterocyclic compounds in 1, 4 dioxane were measured in the temperature range 303.15K to 323.15K. The viscosity was determined by John-Dole equation. The data has been used to calculate Gibb's free energy change (?G), entropy change (?S), and enthalpy change (?H). ?G and ?H are negative and ?S is positive which is indicate the spontaneity of reaction according to thermodynamics.
Licence: creative commons attribution 4.0
Substituted heterocyclic compound, Viscosity, Thermodynamic parameters.
Paper Title: INVISIBLE YET PAINLESS: THE RISE OF MICRONEEDLES TRANSFORMING DRUG, VACCINE AND PHARMACY DELIVERY
Author Name(s): Prachi Shambharkar, Soniya bhongade
Published Paper ID: - IJCRT2608202
Register Paper ID - 312616
Publisher Journal Name: IJPUBLICATION, IJCRT
DOI Member ID: 10.6084/m9.doi.one.IJCRT2608202 and DOI : 2608202_312616
Author Country : Indian Author, India, 411015 , pune, 411015 , | Research Area: Pharmacy All Published Paper URL: http://ijcrt.org/viewfull.php?&p_id=IJCRT2608202 Published Paper PDF: download.php?file=IJCRT2608202 Published Paper PDF: http://www.ijcrt.org/papers/IJCRT2608202.pdf
Title: INVISIBLE YET PAINLESS: THE RISE OF MICRONEEDLES TRANSFORMING DRUG, VACCINE AND PHARMACY DELIVERY
DOI (Digital Object Identifier) : 2608202_312616
Pubished in Volume: 14 | Issue: 8 | Year: August 2026
Publisher Name : IJCRT | www.ijcrt.org | ISSN : 2320-2882
Subject Area: Pharmacy All
Author type: Indian Author
Pubished in Volume: 14
Issue: 8
Pages: b810-b827
Year: August 2026
Downloads: 36
E-ISSN Number: 2320-2882
Microneedle (MN) technology has emerged as a promising strategy for transdermal drug delivery by combining the advantages of hypodermic injections and conventional transdermal systems. MNs are minimally invasive, painless, and capable of enhancing the delivery of small molecules, peptides, proteins, vaccines, and biologics through the skin barrier. This review summarizes skin anatomy relevant to MN-mediated delivery, types of microneedles, fabrication techniques, evaluation parameters, clinical applications, regulatory considerations, and recent advancements in smart and responsive systems. Conventional fabrication methods such as micromolding, photolithography, and laser ablation, along with modern approaches including 3D printing and femtosecond laser micromachining, are discussed. Current challenges involving drug loading, manufacturing scalability, formulation stability, and regulatory approval are also highlighted. Future developments in nanotechnology, biodegradable polymers, biosensors, and artificial intelligence are expected to improve the clinical translation and commercialization of MN-based systems. Overall, microneedles represent a patient-friendly and efficient platform for next-generation transdermal drug delivery and personalized medicine.
Licence: creative commons attribution 4.0
Microneedles, Transdermal Drug Delivery, Skin Anatomy, Drug Delivery Systems, Dissolving Microneedles, 3D Printing, Biosensors

