Volume 8 | Issue 5 |

 Abstract

It is the category of controlled drug delivery system is sub-categories in which drug is delivered through the skin in a predetermined and controlled rate. Nowadays hypertension is one of the most common disorders as found in humans. It is not a disease in itself but is an important risk factor for cardiovascular mortality and morbidity. The present article delivers a brief view of the work that has been done to increase the bioavailability of various antihypertensive drugs by formulated and delivered as transdermal patches. The different drugs include carvedilol, metoprolol, atenolol, propranolol, nicardipine hydrochloride, clonidine, nicorandil, amlodipine. These drugs were penetrating through the various penetration routes into the skin, like appendageal, epidermal, transcellular, intracellular.

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 Keywords

Antihypertension, transdermal, TDDS, NC-HCL, skin, hydrophilic polymer matrix, HPLC

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The study is focused on the combined use of Inquiry based & Reflective pedagogical approaches in complex theoretical lectures in Architecture to gain maximum learning outcome of the learners as Inquiry based Teaching is an excellent path for achieving a goal based partly on the philosophy that �Humans are born Inquirers,� the method focuses on student discovery over pushing information from the instructor. Along the way, the students explore multiple sources and contexts, ask questions and pursue hypotheses, and work to apply their theories to new and diverse situations. In doing this, they actively discover the interrelatedness among concepts, topics, and theories. Inquiry-based approaches are intended to foster critical thinking. By supporting students in their initial Conceptual explorations, more in-depth analyses, and synthesizing processes, these pedagogies deepen the students learning. The next and extreme step of inquiry based teaching leads to Reflective Teaching where self-analysis and evaluation play a very important role. The study will be following empirical approach and will incorporate only direct or indirect overview over Inquiry Based & Reflective Teaching Approach towards the students of B.Arch 1st Year and the focus will be on the complex theoretical classes; the concepts of which in Architecture students find quite inconvenient to understand.

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 Keywords

Active Learning; Architectural Education; Conceptual; Facilitator ; Inquiry-Based Teaching; Pedagogy.

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 Abstract

Operation research is a branch of mathematics whereas Transportation problem is sub-branch of operation research. Transportation Problem can be solved by many methods such as North West Corner Rule (NWC), Least Cost Method (LCM), and Vogel�s Approximation Method (VAM) etc. In this paper we are discussing Least Cost Method for unbalanced transportation problem and way of allocations to dummy row/column. We have made a few modifications in our proposed algorithm which gives minimum cost or nearer to optimal cost.

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 Keywords

Transportation Problem, LCM, VAM, unbalanced transportation problem, Feasible Solution, Optimal Solution

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 Abstract

Pellets are the multiparticulate drug delivery system which prove to be promising and highly flexible system with various kinetics of drug release such as immediate release, sustained and controlled release which are easy to formulate. In order to overcome the physicochemical interaction such as drug-excipient or drug-drug interactions multiparticulate dosage forms can be implemented. The technology of pelletization as oral drug delivery system are gaining substantial attention in the present time. Pelletization is the process where the aggregates of granules or fine powders mixture of drugs and excipients. They form small spherical or semi-spherical free flowing solid units ranging from 0.5 mm to 1.5 mm. Pellets are commonly used as multiparticulate systems as it has technical as well as clinical advantages over single unit dosage forms. The present review focuses on advantages, disadvantages, mechanism of pellet formation, different methods of pellet preparation, characterization of pellets, and also the recent approaches for pelletization techniques.

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 Keywords

Pellets, multiparticulate, pelletization, Granules, Dosage forms, Techniques, Spherical.

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 Abstract

There is a growing need to collect data from the website. In attempting to execute the projects related to data such as price tracking, market analysis, the data from the website will also have to be registered. However, it is out of fashion to copy and paste the data line by line. The Web Scraping project utilizes automation and computing; it uses custom selection criteria to sort Linkedin profiles beyond what is currently available, including position and department. By adding the ability to generate personalized indices of social media data, automated filtration provides companies with the opportunity to boost the use of rich prospective data for more effective customer analysis and targeting.

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Web Scraping, Automation

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Creative Commons Attribution 4.0 and The Open Definition

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Muscle Strength Detection (MSD) system is a diagnostic device that helps in capturing muscle or electromyogram (EMG) signals. The electrical signals are generated as a result of contraction and relaxation of muscle fibers. EMG signal serves as a diagnostic tool for many muscle related disorders namely myasthenia gravis, muscular dystrophy, muscle stiffness, muscle weakness. The system obtains EMG signal from surface electrodes in bipolar lead configuration attached to the biceps through the leads attached to the arm band along with a ground lead placed in wrist region. This raw signal is sent into the detection system, that consists of three units namely pre-amplification, filtering and microcontroller units. The system uses an instrumentation amplifier, a passive low pass filter and an Arduino UNO microcontroller. The major factor of interest in the measurement system is to capture the Maximum Voluntary Isometric Contraction (MVIC) of the particular muscle that describes the muscle strength. The obtained muscle signal is given as input to Arduino microcontroller for detecting muscle strength using different colored feedback Light Emitting Diodes (LEDs). Each corresponding LED indicate a specific muscle strength: very low, low, medium, high and very high respectively. Thus, the MSD system is useful to a great extent for the following applications such as muscle diagnosis, treatment, rehabilitation, and measuring physical fitness. Above mentioned EMG signals, muscle anomalies, principle behind signal acquisition, objective, novelty, various blocks, maneuver for obtaining signal, steps for usage, future scope will be discussed in greater detail in the upcoming sections.

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 Keywords

EMG signal, Muscle strength detection, Maximum voluntary isometric contraction, Arduino UNO

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 Abstract

The medicinal plant Asparagus racemosus is a tropical and subtropical plant spread over India. The medicinal uses of the plant is already established in different standardize books in pharmaceuticals. The plant has shown numerous pharmaceutical importance in the crude as well as the extracted form.Several active metabolites have been isolated from this plant like saponins,sarasapogenis,flavonoids, rutin,qurecetin,alkaloids etc. My study was aim to give in details of phytoharmacological study of the plant Asparagus racemosus.

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Saponins, Sarasapogenis, flavonoids, rutin, qurecetin and alkaloids

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

In addition to the rapid growth of urban population size, demands for more offices and facilities are being created step by step. The use of Internet-of-Things (IoT) software and the insightful framework is a profitable and effective way to tackle urban planning issues. The interconnection and communication of several thousand IoT devices on the web leads to enormous data, known as Big Data. The reconciliation of IoT with the development of huge amount of information along a systematic route to the development of keen cities is critical. In order to resolve this problem, structure for brilliant urban development in the light of IoT using the investigation of Huge Knowledge will be useful. Sensors sending data is used like smart home sensors, vehicle system administration, environment and additional water sensors, shrewd stop sensors, and objects of observation, etc. The collected information is constantly prepared for sharp urban zones that use Hadoop with Start, from all the brilliant frameworks. System use existing datasets of different experts, including support, skilled homes, shrewd stoppage, use of advanced cells, climate control and vehicle speed control for inspection and testing. System uses existing data sets. To check the continuous competence of this system, all data sets are replayed. I eventually assessed the system by performance skills and preparation time. The result of the study shows that the proposed system structure is adaptable and comprehensive.

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 Keywords

big data,IoT,Smart city, Smart home

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Creative Commons Attribution 4.0 and The Open Definition

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The study titled, �Regional Scenario of Financial Inclusion: Banks and Microfinance Services� empirically investigates the status of financial inclusion deepening, and flow of financial services all the regions of India i.e. central, eastern, northern-eastern and northern, southern, western, region. This study using different mode of financial services i.e. commercial banks services, Microfinance services (SHG related). Method used here is percentage Share of financial services across the region in for 2006 to 2016 period. Findings revealed that there tremendous growth captured in all three modes of services from 2006 to 2016. Further study reveals the gaps which also attracts attention toward these indicators and also found that the significant differences prevail in the inflow of financial services in all regions in India. Highest percentage share flows to South region states and lowest in North- East region states. While, credit indicators of Formal bank, Microfinance services, shows that heavy inflow in the particular region rather outflow of deposit indicators.

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 Keywords

Banking services, Microfinance, Regional Imbalance.

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

It is our misfortune that the whole world is in trouble due to attack of Corona virus. In these circumstances both teachers and students are facing some real problem of imparting and acquiring knowledge. E-learning is the only solution to cope up with the situation; however it is not very easy for both teachers and students to make them prepare for this new kind of e-class because the situation is not very conducive. Society is passing through a crisis situation and the entire institutional system is closed. Due to long term lockdown both teachers and students have no options other than e-class for completion of their course. But rural poor students of backward section of society who are 1st generation learner are in absolute crisis because either they have no Smartphone to participate in this modern format of teaching-learning or have no internet facility in their remote location.

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 Keywords

E-class, Online class, E-learning, Online teaching-learning, Social Media Learning

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Creative Commons Attribution 4.0 and The Open Definition