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INTERNATIONAL JOURNAL OF CREATIVE RESEARCH THOUGHTS - IJCRT (IJCRT.ORG)
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ISSN Approved Journal No: 2320-2882 | Impact factor: 7.97 | ESTD Year: 2013
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Paper Title: In Silico Designing, Validation and In-Vitro Synthesis of YPS1 Silencing siRNAs
Author Name(s): Nipunjot Kaur Soni-Bains
Published Paper ID: - IJCRT1133055
Register Paper ID - 190418
Publisher Journal Name: IJPUBLICATION, IJCRT
DOI Member ID: 10.6084/m9.doi.one.IJCRT1133055 and DOI :
Author Country : Indian Author, 147002, India , Patiala, India , | Research Area: LifeSciences Published Paper URL: http://ijcrt.org/viewfull.php?&p_id=IJCRT1133055 Published Paper PDF: download.php?file=IJCRT1133055 Published Paper PDF: http://www.ijcrt.org/papers/IJCRT1133055.pdf
Your Paper Publication Details:
Title: IN SILICO DESIGNING, VALIDATION AND IN-VITRO SYNTHESIS OF YPS1 SILENCING SIRNAS
DOI (Digital Object Identifier) :
Pubished in Volume: 2 | Issue: 2 | Year: June 2014
Publisher Name : IJCRT | www.ijcrt.org | ISSN : 2320-2882
Subject Area: LifeSciences
Author type: Indian Author
Pubished in Volume: 2
Issue: 2
Pages: 303-313
Year: June 2014
Downloads: 1809
E-ISSN Number: 2320-2882
Abstract
Fission yeast is a useful model for RNA interference because it has single-copy genes for components of the RNAi pathway such as argonaute, dicer and RNA-dependent RNA polymerase (RdRP) (Wood, V. et al., 2002). Schizosaccharomyces pombe has DCR and AGO but not in Saccharomyces cerevisiae (Verdel, A. et al. 2004). Studies till date have proved that RNAi machinery in fission yeast has only epigenetic effects as they help in histone modifications. Present study involved designing of siRNAs against fission yeast protease yps1. Critical design concerns in the selection of siRNA duplexes that are potent and specific.
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Volume 13 | Issue 10
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Submit Manuscript Online Impact Factor: 7.97 Review Results : Within 02-03 Days Paper Publication : Within 02-03 Days
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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