Published Paper Details:

Cissus quadrangularis is a common succulent perennial climber. It is also known as 'Hadjod', is a medicinal plant that has been extensively used in traditional herbal medicine, particularly in the Ayurvedic systems of healing. This review aims to consolidate recent advances in the pharmacological and therapeutic properties of Cissus quadrangularis, focusing on its potential in treating bone-related disorders, metabolic conditions, and other ailments. The plant is rich in bioactive compounds such as flavonoids, triterpenoids, and phytosterols, which contribute to its anti-inflammatory, antioxidant, and anabolic properties. Research has demonstrated its efficacy in enhancing bone healing, reducing fractures, and improving bone mineral density, making it a promising candidate in osteoporosis treatment. Additionally, Cissus quadrangularis has shown potential in managing obesity, diabetes, and cardiovascular conditions, primarily through its modulation of lipid profiles and blood glucose levels. This review mainly highlights the therapeutic use of the plant. Despite its long-standing use in traditional medicine, further clinical studies and standardization of extracts are required to fully establish its efficacy and safety for broader medical applications.