Published Paper Details:

The present study focuses on the formulation and evaluation of polyherbal anti-diabetic granules for the effective management of diabetes mellitus, a chronic metabolic disorder characterized by elevated blood glucose levels and associated complications. The limitations and side effects of conventional synthetic drugs highlight the need for safer and more effective herbal alternatives.In this study, a polyherbal formulation was developed using Aegle marmelos, Gymnema sylvestre, and Momordica charantia, which possess well-established antidiabetic properties through multiple mechanisms such as reducing glucose absorption and improving insulin activity. The granules were prepared by the wet granulation method using suitable excipients including diluents, binders, lubricants, and flavoring agents.The prepared granules were evaluated for various pre-compression and post-formulation parameters such as angle of repose, bulk and tapped density, Carr's index, Hausner's ratio, particle size distribution, and moisture content. Further evaluation included phytochemical screening, organoleptic properties, and in-vitro antidiabetic activity using enzyme inhibition assays. Sachet evaluation tests were also performed to ensure uniform ity and quality.The study concludes that polyherbal anti- diabetic granules are a stable, effective, and patient- friendly dosage form with promising potential in the management of diabetes mellitus.