Published Paper Details:

The main objective of this project is to formulate and evaluate polyherbal anti-diabetic tablet with enhanced disintegration time.The polyherbal tablet consist of five traditional herbs Gurmar (Gymnema sylvestre), Karela (Momordica charantia), Tulsi (Ocimum sanctum), Ginger (Gingiber officinate), Cinnamon (Cinnamum zelacicum). In the formulation the Gurmar (leaf powder dry) , Karela (dry fruit powder) , Tulsi (dry leaf powder), Ginger (dry root powder) , and Cinnamon (bark powder) were used. The polyherbal tablets were prepared by wet granulation method with excipients: Gum Acasia, Polyvinylpyrrolidine, Aerosil, Talc, and Magnesium Stearate.. The preliminary phytochemical analysis of powder mixture was done using the methanolic extract of powder mixture. The preformulation studies of tablets were performed including Angle of repose, tapped density, bulk density, carr's index, hausner's ratio. The dried polyherbal remove was streamlined for its quality measures and its cluster consistency by making 5 diverse preliminary clumps(Trial 1,2,3,4,5). The preliminaries were exposed to preformulation boundaries to confirm the consistency and quality. The outcome assumes that the initial five formulations demonstrated across all parameters, and were therefore utilized to create a detailed polyherbal tablet formulation. The developed polyherbal phytochemical study showed the presence of flavonoids, alkaloids, tannin, phenolic compound in the formulation by using phytochemical analysis. The laboratory scale preparation of polyherbal tablet can lead to new powerful and oral dosage formulation for diabetes mellitus and lighten by synergic area of action herbs.