Published Paper Details:

Maintaining effective hand hygiene will essential for preventing the spread of infectious microorganisms. Increasing concerns regarding the frequent use of synthetic hand sanitizers, such as skin irritation and dryness, have encouraged the development of safer, plant-based alternatives. The presented study focused on the preparation and evaluation of a polyherbal hydroalcoholic hand sanitizer formulated using natural ingredients with proven antimicrobial activity. The formulation was designed by incorporating neem (Azadirachta indica) extract obtained by aqueous extraction, clove (Syzygium aromaticum) oil extracted through hydro-steam distillation, and fresh aloe vera (Aloe barbadensis) gel, along with 70% ethanol as the primary antimicrobial agent. Tween 80 was used as a surfactant, glycerine as a humectant, and rose oil for fragrance. The combination of neem and clove was select to achieve a synergistic bactericidal effect, enhance the overall antimicrobial efficiency of the formulation. The prepared sanitizer was evaluate for physicochemical parameters including pH, spreadability, appearance, and stability.