Published Paper Details:

Microplastic pollution represents a severe, escalating systemic threat to global public health and environmental integrity. These persistent polymer fragments--measuring between 1 nm and 5 mm--infiltrate biological systems via oral ingestion, inhalation, and dermal exposure. Once inside the organism, they resist standard elimination mechanisms, accumulate chronically within vital organs, and trigger low-grade tissue vitiation. This paper establishes a comprehensive conceptual bridge between the contemporary toxicology of microplastics and the classical Ayurvedic framework of Dushi Visha (attenuated, latent, or cumulative toxins). Historically defined by Acharya Sushruta as an altered, low-potency poison that evades total metabolic expulsion due to encapsulation by Kapha dosha, Dushi Visha remains dormant until environmental or metabolic triggers cause system-wide disruption.This paper analyzes classical texts (Sushruta Samhita, Charaka Samhita, and Ashtanga Hridaya) alongside modern toxicological profiles of polymers like Polyethylene (PE), Polystyrene (PS), and Polyvinyl Chloride (PVC). Our findings indicate a 90% functional alignment between the pathodynamics of microplastic bioaccumulation and the clinical stages of Dushi Visha. Both entities display identical properties of low immediate lethal potency (Alpa-veerya), high tissue affinity (Dhatu-pradushana), and aggravation by environmental shifts (Kala and Desha). This cross-disciplinary synthesis provides an innovative, integrative therapeutic model. It combines contemporary cellular detoxification strategies with traditional Ayurvedic Agada Tantra protocols (Dushivishari Gulika and Panchakarma) to mitigate the chronic burden of plastic accumulation in the human body.