Published Paper Details:

Dengue fever is a mosquito-borne viral disease that has become a major public health concern in tropical and subtropical regions. The absence of specific antiviral therapy has increased the demand for alternative and supportive treatments using herbal medicines. The present study focuses on the formulation and evaluation of a herbal papaya syrup prepared from Carica papaya leaf extract for supportive management of dengue fever. Papaya leaves are rich in phytoconstituents such as flavonoids, alkaloids, phenolic compounds, and enzymes which are reported to possess immunomodulatory, antioxidant, and platelet-enhancing activities. The papaya leaves were collected, shade dried, powdered, and extracted using water under controlled conditions. The prepared extract was formulated into syrup using sugar syrup as a base along with Vitamin B12, selenium, sodium benzoate, and distilled water. The formulated syrup was evaluated for various physicochemical parameters including visual appearance, aroma, taste, pH, solubility, refractive index, viscosity, and physical stability. The results showed that the syrup possessed a uniform greenish appearance, pleasant aroma, acceptable sweetness, and good palatability. The pH of the formulation was found within the acceptable range of 6-7, indicating suitability for oral administration. The syrup exhibited good solubility, appropriate refractive index, and satisfactory viscosity. Stability studies indicated absence of crystallization, microbial growth, or phase separation. The study concludes that the formulated herbal papaya syrup possesses satisfactory pharmaceutical properties and may serve as a supportive herbal formulation for dengue patients. Further pharmacological and clinical studies are required to establish its therapeutic efficacy and safety on a larger scale.