Published Paper Details:

Dry Eye Syndrome (DES) is a multifactorial ocular surface disorder characterized by tear film instability and inflammatory changes, presenting with symptoms such as dryness, burning sensation, foreign body sensation, redness, and ocular fatigue. In Ayurveda, DES correlates with Shushkakshipaka, caused mainly by vitiation of Vata and Pitta Doshas. Conventional treatment with artificial tears like Carboxymethylcellulose (CMC) provides symptomatic relief but has limited long-term benefits. This randomized, controlled clinical study evaluated the add-on effect of Bhringarajaadi Tail Pratimarsha Nasya with CMC 0.5% eye drops in DES. Sixty patients were randomly divided into two groups of 30 each. Group A received Bhringarajaadi Tail Pratimarsha Nasya along with CMC eye drops, while Group B received CMC eye drops alone for 15 days. Subjective symptoms and objective parameters (TBUT and Schirmer-I test) were assessed. Statistical analysis using paired t-test, unpaired t-test, and Mann-Whitney U test showed highly significant improvement in both groups (p < 0.001), with Group A demonstrating superior results. The study concludes that the integrative approach is more effective and safe in the management of Dry Eye Syndrome.