Published Paper Details:

Histopathological Evaluation Of Thyroid Lesions Dr Nisarg Shah, 3rd-year Resident Dr Shivani Divecha, 3rd-year Resident Dr Ayushi Shah, 2nd-year Resident Dr. Shashikant Mavadiya, Professor Dr. Vaibhavi Thacker, 2nd-year Resident Department of Pathology, Dhiraj Hospital, SBKS Medical Institute & Research Centre. Corresponding Author - Dr Nisarg Shah Email ID: nisargshah96ns@gmail.com Contact number - 8511348204 BACKGROUND: Histopathological evaluation is essential for the definitive diagnosis of thyroid lesions, particularly in differentiating follicular adenoma from follicular carcinoma, which significantly influences patient management and prognosis. OBJECTIVES: To study the spectrum of thyroid lesions and evaluate their histopathological patterns and to analyze their distribution across age and sex. METHODS: A retrospective observational study was conducted in the Histopathology section of the Department of Pathology, Dhiraj Hospital, SBKS MI & RC, Vadodara, from September 2024 to October 2025. A total of 58 specimens--including tru-cut biopsies, lobectomies, hemithyroidectomies, subtotal, and total thyroidectomies--were included. Inadequate or autolysed specimens were excluded. Tissue samples were fixed in 10% neutral buffered formalin, stained with hematoxylin and eosin, and examined microscopically. Data were analyzed using Microsoft Excel. RESULTS: Patients ranged from 22-66 years, with a marked female predominance (M:F = 1:7). Non-neoplastic lesions were more common than neoplastic lesions. Among neoplasms, benign tumors predominated. Follicular adenoma was the most frequent benign lesion, while papillary thyroid carcinoma was the most common malignant tumor. CONCLUSION: This study highlights that non-neoplastic and benign neoplastic thyroid lesions are more prevalent than malignant lesions. Despite the availability of preoperative diagnostic tools, histopathology remains the gold standard for accurate diagnosis and optimal management of thyroid diseases.