Published Paper Details:

Calendula officinalis L., commonly known as pot marigold, is one of the most extensively used medicinal plants in traditional and complementary medicine systems worldwide. Belonging to the Asteraceae family, this herb has been employed for centuries in the management of wounds, inflammatory disorders, gastrointestinal disturbances, and skin ailments. Contemporary scientific investigations have revealed that its therapeutic potential is closely associated with a diverse spectrum of bioactive compounds, including flavonoids, triterpenoids, carotenoids, phenolic acids, coumarins, quinones, and essential oils. Experimental studies, supported by growing clinical evidence, demonstrate antioxidant, anti-inflammatory, antimicrobial, hepatoprotective, antidiabetic, cytotoxic, and wound-healing activities. In addition to validating traditional claims, modern research has begun to clarify the molecular pathways responsible for these biological effects. This review provides a comprehensive and updated synthesis of phytochemical composition, pharmacological mechanisms, therapeutic applications, extraction technologies, and future research directions. The aim is to offer an integrated scientific perspective that supports the rational and evidence-based utilization of C. officinalis in modern healthcare