Published Paper Details:

Background: V?ta Do?a is considered the primary regulatory principle governing all physiological movements and functional activities in Ayurveda. Classical Ayurvedic texts describe V?ta as responsible for neural communication, sensory perception, motor activity, respiration, circulation, and excretory functions. These descriptions demonstrate close functional similarity with the regulatory role of the nervous system described in modern neurophysiology. Objective: To analyze the Ayurvedic concept of V?ta Do?a and correlate its physiological functions with modern neurophysiological principles, with special reference to the therapeutic role of Basti therapy. Methods: A narrative integrative review was conducted based on classical Ayurvedic literature, including Charaka Sa?hit? and A????ga H?daya, along with contemporary scientific literature from standard physiology textbooks and peer-reviewed journals related to neurophysiology, enteric nervous system, gut-brain axis, and neuroenteric regulation. Classical descriptions were critically interpreted and correlated with modern scientific concepts. Results: Classical Ayurvedic descriptions identify V?ta Do?a as the governing factor of movement, communication, and coordination within the body. Functional attributes of V?ta show conceptual parallels with neural impulse transmission, autonomic regulation, and systemic physiological integration. The colon (Pakv??aya), described as the principal seat of V?ta, corresponds functionally with the enteric nervous system and gut-brain axis recognized in modern science. Basti therapy, administered at the primary seat of V?ta, may exert therapeutic effects through modulation of enteric neural activity, autonomic balance, and neuroendocrine signaling. Conclusion: An integrative interpretation suggests that V?ta Do?a represents a neurophysiological regulatory principle coordinating bodily functions. Understanding Basti therapy through gut-brain axis mechanisms provides a scientific perspective for traditional Ayurvedic practice and supports the development of integrative therapeutic approaches for neurological and functional disorders.