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The research design chosen for the study was one group pretest posttest design and the research approach was an quantitative approach. This study Design: The approach of the study was descriptive survey approach with case and control research design was utilized to conduct this study. undertaken in Sri Lakshmi Public School at Bangalore. The data was collected through the tool which is prepared by the investigator. The sample size consists of 60 primary school children. The collected information was organized, tabulated, analyzed and interpreted using descriptive and inferential statistics. Analysis was done based on the objectives and hypothesis of the study. The level of significance was set at 0.05 levels. RESULT : Pre-test assessment of level of knowledge indicates that only one-fifth of the subjects were having a moderate amount of knowledge. Remaining 80% were having inadequate level of knowledge and none was holding adequate knowledge. The Mean, SD and Mean% of the pretest general knowledge of primary school children are 12.1, 4.1, and 40.3% respectively Post-test level of knowledge has an amazing 46.6% subjects showed adequate level of knowledge and the remaining 53.3% showed moderate level of knowledge. No subjects appeared with inadequate knowledge post-testily. Mean found 20.7 SD found to be 2.7 and mean percentage, after treatment, changed to 69.1.8%: Compares pretest and posttest levels of knowledge, before self-instructional module80% of the subjects had inadequate level of knowledge and the remaining 20% had moderate level of knowledge. However, after self-instructional module the subjects' level of knowledge improved significantly. 46.7% of the subjects, after self-instructional module showed adequate level of knowledge and the remaining 53.3% showed moderate knowledge. Paired t test was calculated to analyze the difference in pre and post-test knowledge scores of student nurses which show significant difference between the overall scores. Hence the hypothesis H1 is accepted and it can be interpreted that the difference observed in the mean score of the pre and post score were true difference. Conclusion : The primary school children in rural primary school have lacked knowledge regarding personal hygiene and its importance. The pre-test mean score was 20.7. The self-instructional module was very effective in improving the knowledge, since post-test score was found to be significant (46.7). From these findings it could be concluded that, self-instructional module is an effective strategy in improving the knowledge of primary school children regarding, personal hygiene and its importance