Published Paper Details:

Background: Polyarthralgia in the context of febrile illnesses is frequently encountered in clinical practice and is prominent in post-infective states. Ayurveda describes Guduchi (Tinospora cordifolia), honored as "Am?ta," as a premier Ras?yana with Jvaraghna, Shothahara, and Ved?n?sth?pana actions. Classical attributes--Tikta-Ka??ya rasa, Laghu-Snigdha gu?a, U??a v?rya, and Madhura vip?ka--suggest a rationale for its use in fever-associated joint pain that often has an ?ma component. Objective: To clinically evaluate the utility of Guduchi administered as Sa??aman? Va?i in relieving polyarthralgia associated with febrile conditions, while grounding the rationale, posology, and assessments in Ayurvedic textual principles. Methods: A pragmatic case-series of five adult patients with fever and concomitant polyarthralgia received Sa??aman? Va?i (two tablets, three times daily) for five days with u??a jala as anup?na. Outcomes were tracked daily using patient-reported pain (0-10 VAS), morning stiffness minutes, painful joint count, fever log, and an ?yurvedic ?ma-Agni symptom scale. Dietary and behavioral pathy?-apathy? were counseled per classics. No modern journal data were used to frame the rationale; all interpretive frameworks reference classical Ayurveda. Results: All patients reported 75-80% improvement in global joint pain by day 5, with concordant reductions in stiffness, painful joint counts, and resolution of fever. Appetite, lightness, and sleep improved in parallel, suggesting favorable shifts in Agni and Do?a-?ma status. No adverse effects were recorded. Conclusion: Within the Ayurvedic paradigm, Guduchi--administered as Sa??aman? Va?i--appears to be a safe, fast-acting, and systemically supportive intervention for febrile polyarthralgia, likely via Deepana-P?cana, Jvaraghna, V?ta-Kapha ?amana, Shothahara, and Ras?yana effects. The present case-series, while limited in size and duration, aligns closely with classical descriptions and supports further controlled exploration.