Published Paper Details:

Nanoboats represent a cutting edge class of nanoscale delivery vehicles inspired by biological propulsion mechanisms and engineered for enhanced targeting, controlled release, and precision therapy. These nanosystems integrate navigation strategies derived from motor proteins, synthetic swimmers, and nano propellers with advanced drug encapsulation techniques to traverse physiological barriers. This review synthesizes recent advances in nanoboat design, propulsion mechanisms, therapeutic payload integration, targeting strategies, and clinical translation challenges. We discuss key propulsion technologies -- from catalytic and magnetic fields to biohybrid designs -- and analyze their impact on delivery efficiency, tissue specificity, and biocompatibility. Finally, we assess current limitations, safety concerns, and future directions in harnessing nanoboat systems for targeted cancer therapy, neurological treatments, and personalized medicine applications.