Published Paper Details:

Background: Proliferative diabetic retinopathy (PDR) is an advanced microvascular complication of diabetes mellitus and a major cause of visual impairment. In Ayurveda, long-standing diabetic retinal pathology can be correlated with Madhumehajanya Timira, resulting from chronic Prameha associated with Agnimandya, Ama and Rakta-Meda Dushti affecting the Drishti Mandala. Conventional management primarily aims at preventing further progression, highlighting the need for supportive and holistic therapeutic approaches. Aim: To assess the role of Ayurveda in managing Madhumehajanya Timira corresponding to long-standing proliferative diabetic retinopathy. Materials and Methods: A patient diagnosed with long-standing proliferative diabetic retinopathy was treated using a comprehensive Ayurvedic regimen. Internal medications included Chitrakadi Vati, Nishamalaki Choorna, Brihat Vasakadi Kashaya and Triphala Choorna combined with Shuddha Shilajatu. External therapies (Kriyakalpa) such as Nasya with Anu Taila, Thalam with Amalaki kalka sadita Dadhi, Bidalaka using Mukkadi Choorna, Durva Swarasa and Vata Shringa, along with Takradhara were administered. Clinical assessment was based on subjective visual symptoms and fundoscopic and OCT findings. Results: The patient showed improvement in visual comfort with stabilization of vision and no further progression of neovascular changes during the treatment period. Systemic well-being and better glycemic stability were also observed. Conclusion: Ayurvedic management may help in stabilizing disease progression and improving ocular comfort in Madhumehajanya Timira corresponding to long-standing proliferative diabetic retinopathy. An integrative approach addressing systemic metabolic derangements along with ocular pathology can be beneficial as supportive care. Further studies are required to validate these observations.