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The ancient Ayurvedic text Sushruta Samhita describes wound management in the Vranitopasaniya Adhyaya, emphasizing various herbal and oil-based preparations for effective healing. However, these formulations still require systematic scientific validation. This case study presents an integrative Ayurvedic approach for managing a chronic non-healing wound arising from an arteriovenous malformation (AVM). A 58-year-old female presented with an ulcer on the dorsum of the right foot, characterized by mild pain, edema, and eczematous changes, persisting for approximately three months (90 days). The underlying condition was suggestive of AVM over the plantar aspect of the same foot, with a documented history of approximately 10 years, characterized by recurrent episodes of bleeding ulcers. An Ayurvedic treatment protocol was administered over a period of 90 days, involving daily wound cleaning with Betadine solution and daily dressing with topical application of Ropan Taila, ShodhanTail, Yashtimadhu Ghrita along the period. Oral medications included Yograj Guggulu (500 mg, twice daily), Sukshma Triphala Vati (400 mg, twice daily), Aarogyavardhini Vati (400mg, twice daily), Chandraprabha Vati (400 mg,twice daily), Gandhak Rasayan, Lohasav and Mahamanjishthadi Kadha (7 ml, twice daily). Clinical assessment were conducted at baseline (day 0) and subsequently on days 15, 30, 45, 60, 75 and 90. The treatment demonstrated marked improvement in wound epithelialization, reduction in exudates, and absence of allergic or adverse reactions, supporting the efficacy of ayurvedic medicines in chronic wound management.