Published Paper Details:

Sushrut Samhita and Charak Samhita are the two major ancient texts of Ayurveda. Both the Samhitas cover surgical and conservative aspects of treatment modalities respectively and are a part of Brihatrayee. As Ayurveda is a science of life, the treatment protocols mentioned here are of natural origine and carry immense potential to cure a disease from it's root, avoiding recurrence and minimizing the possible complications that may be seen in contemporary treatment. UTI1 may be defined as a condition in which the bacteria invades, persists and multiplies within the urinary tract. 13 types of Bastirogas mentioned in the Trimarmiyasiddhi adhyaya2 from Charak Samhita mainly focuses on vyadhis caused by vitiation of Vata dosha with Pitta and Kapha being the Awarakas (Covering agents). In Mutrakricchra, urinary tract infections can occur due to various bacteria, potentially leading to severe infections. A significant issue worldwide is the multidrug resistance of these bacteria to antimicrobial drugs. Additionally, contemporary treatments often come with unwanted side effects. Therefore, exploring new sources of antimicrobial agents and evaluating the effectiveness of drugs mentioned in ancient texts is both valuable and necessary. Chandraprabha Vati and Gokshuradi guggul vati has been studied for their action on Mutravaha strotas. The present clinical study has been conducted to evaluate the combined role of Chandraprabha vati and Gokshuradi Guggul vati in the management of Mutrakricchra.