Published Paper Details:

Context: Multiple sclerosis (MS) is a progressive demyelinating disease of the white matter of the central nervous system. The disorder is found more commonly in young adulthood, out of which women represent a huge stakeholder group, which is approximately 70% of the total affected population. Common symptoms usually represent general fatigue, muscular weakness, spasticity, ataxia, sensory disturbances, cognitive and autonomic dysfunctions, with a very low level of daily physical activity due to detraining and deconditioning. The study's objective was to determine the effect of the exercise training program as a part of an inpatient rehabilitation program on various systems of the body. Study Designs and Settings: This case report was conducted in the OPD at the Maharashtra Institute of Physiotherapy, Latur, Maharashtra. Methods: A 30-year-old female who was diagnosed case of relapsing remitting multiple sclerosis was referred to our center for outpatient rehabilitation. The patient receives a Structured aerobic exercise programme, Treatment for low back pain, Progressive resistance exercises (PRE) for improving the strength of upper and lower limbs, Kegel's exercises for PFM strengthening, and Exercises to improve the strength of core muscles. The intervention was given 5 days a week for 8 weeks. Outcome measures was 6 minute walk test (6MWT), PFT, Peripheral oxygen saturation (SPO2), fatigue severity scale, numerical pain rating scale NPRS, Heart Rate (HR), Systolic and Diastolic blood pressure (B.P), Berg Balance Scale for balance assessment, Multiple Sclerosis Quality Of Life(MSQOL)-54 Instrument. Results: 6 minutes walking distance, which is increased by 60 meters. A MIC adjusted for improvement of 19.7 m (95%CI 9.8-30.9 m) was found in one study, improvement of 19.7 m (95%CI 9.8-30.9 m) was found in one study, There was no significant changes was observed in PFT FEV1:85 & FEV1/FVC RATIO:0.8 which was improved by FEV1:90 & FEV1/FVC RATIO:0.8, Fatigue severity scale score was increased by 16 points, NPRS 8 before intervention which was reduced to NPRS 3 after 8 weeks, MSQOL-54 score was increase from 20/30 to 25/30, Berg balance scale score was increased from 51/56 to 54/56, Pelvic floor muscle function would not show any significant improvement. Conclusion: findings have concluded that managing the MS patient as a whole and considering every system can lead to significant improvement in as a therapeutic protocol to restore patient mental health, improve the general QoL, and fatigue that occurs in this patient.