Published Paper Details:

Fast disintegrating tablets have possible advantages over usual dosage forms, with improved patient observance, convenience, bioavailability and rapid onset of action. They are good substitute for drug delivery to geriatric and paediatric patients. They have major advantages of both solid and liquid dosage forms, as they remain solid during storage, which assist in stability of dosage forms and transform into liquid form within few seconds after its administration Thus FDT has great scope for being immediate drug delivery. The Loratidine are used as a model drug in the preparation of formulation. It is generally used for the treatment of Asthma. It is safe well tolerated. The study began with the preformulation characterization of drug which involves determination of melting point and development of suitable analytical method for the estimation of drug. The direct compression approach was used to create fast-dissolving tablets. It was discovered that the disintegration time of medication tablets made via direct compression was between 30 and 40 seconds. The best results were obtained from tablets manufactured with the highest amount of Crospovidone, or F15. According to the dissolving study's findings, almost half of the medication was released in the first five minutes.