Published Paper Details:

Introduction: Post-stroke depression (PSD) is one of the most common complications of stroke with a prevalence of 55%. It limits the recovery of a patient's motor and cognitive functions and also affects the rehabilitation and quality of life. The present study aims to compare the effect of Transcranial Direct Current Stimulation and Virtual Reality on Post-Stroke Depression. Methods and materials: In this study 20 participants were included and were randomized into two groups. Stroke patients with post-stroke depression between the age group of 21-75 years old of both genders were included. They were allocated to two groups ie. Virtual Reality coupled with conventional physiotherapy (Group A) and Transcranial Direct Current Stimulation coupled with conventional physiotherapy (Group B) by envelope method. The primary outcome measure was the Hamilton Depression Rating Scale (HDRS) and the secondary outcome measures were the Montreal Cognitive Assessment Scale (MOCA) and Functional Independence Measure (FIM). Results: Statistical analysis showed significant improvement across all measures in both groups. However, participants in the VR group demonstrated greater reductions in depression scores, enhanced cognitive performance, and improved functional independence compared to those receiving tDCS. Conclusion: The present study concluded that Virtual Reality improved post-stroke depression, cognitive function, and activities of daily living (ADLs) in patients with post-stroke depression