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Background: Generalized Anxiety Disorder (GAD) is a chronic mental health condition characterized by persistent, excessive, and free-floating anxiety occurring more days than not and often accompanied by autonomic overactivity and somatic manifestations such as headache, restlessness, muscle tension, fatigue, and sleep disturbances. The disorder significantly impairs daily functioning, concentration, and overall quality of life. Epidemiological studies suggest that GAD is more prevalent among middle-aged and elderly individuals, particularly women, and is frequently associated with prolonged psychosocial stress, bereavement, interpersonal conflicts, and unresolved emotional trauma. Conventional management of GAD primarily includes pharmacotherapy and psychotherapy, which may provide symptomatic relief but often require long-term treatment and may be associated with adverse effects or incomplete resolution of symptoms. Furthermore, these approaches may not always address the individual's emotional susceptibility or the deeper psychosomatic dimensions of the disorder. In homoeopathy, mental disorders are understood as dynamic disturbances of the vital force, frequently arising from prolonged emotional stress, grief, disappointment, or suppressed emotions. According to homoeopathic philosophy, psychological disturbances often manifest through physical symptoms, and such somatic expressions are considered meaningful indicators of internal imbalance rather than isolated pathological entities. Therefore, treatment is directed toward the individual as a whole, based on the totality of mental, emotional, and physical symptoms, with the aim of restoring equilibrium and achieving sustained improvement rather than mere symptomatic palliation. Case: A 54-year-old female presented with chronic headaches for 3-4 years associated with excessive worry, restlessness, cold perspiration during anxiety, disturbed sleep, irritability, and craving for raw rice. The complaints followed prolonged marital stress, domestic abuse, bereavement, and subsequent betrayal by family members. Intervention: Based on the totality of symptoms and repertorial evaluation, Natrum muriaticum was prescribed as the constitutional remedy. Conclusion: This case highlights the importance of constitutional homoeopathic treatment in managing Generalized Anxiety Disorder with somatic expression.