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  Published Paper Details:

  Paper Title

Non-Invasive Optical Biosensing: A Hybrid NIRS-PPG Approach for Blood Parameter Estimation

  Authors

  Swapnil K. Shelke,  Dr. Deepak S. Dhote

  Keywords

Haemoglobin, oxygen saturation, non-invasive, Near-infrared spectroscopy, photophethysmography

  Abstract


Haemoglobin, oxygen, platelets, red and white blood cells, and plasma are some important parameters of blood. As haemoglobin carries oxygen from the lungs to the body and returns carbon dioxide to the lungs, haemoglobin and oxygen saturation are very important. Their levels are important for the diagnosis of number of diseases. Haemoglobin concentration is currently determined via invasive blood sample, which is unsuitable for real-time patient monitoring during crises due to its inconvenience and analysis delays. In this study, we have used Photoplethysmography (PPG) and Near-infrared spectroscopy (NIRS) to measure blood haemoglobin and Oxygen saturation level non-invasively. Here we have developed multi wavelength photometric system containing LED's of different wavelength (550, 660, 810, 940 nm) and photo detector. Signal from the sensor system is given to the microcontroller for the further processing and displays using LCD display. In this study we take 25 volunteers of different age group that are suggested for Complete blood count or Haemoglobin test by the doctor or medical practitioner. Proposed non-invasive haemoglobin measurement have significant positive linear association with a correlation coefficient of r is 0.9318 (? <0.0001) with mean bias of 0.5280 g/dL and limits of agreement (95%) ranging from -0.6391 to +1.6951 g/dL as compared to invasive standard laboratory method. In case of Oxygen saturation correlation values of r is 0.6123 (? <0.0001) with mean bias of 0.3200% with 95% LoA ranging from -1.440% to +2.0840%.

  IJCRT's Publication Details

  Unique Identification Number - IJCRT25A1308

  Paper ID - 299707

  Page Number(s) - i783-i791

  Pubished in - Volume 13 | Issue 12 | December 2025

  DOI (Digital Object Identifier) -   

  Publisher Name - IJCRT | www.ijcrt.org | ISSN : 2320-2882

  E-ISSN Number - 2320-2882

  Cite this article

  Swapnil K. Shelke,  Dr. Deepak S. Dhote,   "Non-Invasive Optical Biosensing: A Hybrid NIRS-PPG Approach for Blood Parameter Estimation", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.13, Issue 12, pp.i783-i791, December 2025, Available at :http://www.ijcrt.org/papers/IJCRT25A1308.pdf

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ISSN: 2320-2882
Impact Factor: 7.97 and ISSN APPROVED
Journal Starting Year (ESTD) : 2013
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ISSN and 7.97 Impact Factor Details


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ISSN
ISSN: 2320-2882
Impact Factor: 7.97 and ISSN APPROVED
Journal Starting Year (ESTD) : 2013
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