Published Paper Details:

Chronic Kidney Disease (CKD) is a growing public health crisis worldwide. In 2021 alone, approximately 673.7 million people were living with CKD, accounting for about 8.5% of the global population--a sharp increase compared to 1990.1 Population aging and growth are key drivers of this increasing burden. CKD has even emerged as the third fastest-growing cause of death globally among non-communicable diseases. Notably, CKD disproportionately affects low- and middle-income countries (LMICs), where healthcare infrastructure is often insufficient to meet rising demand. Despite advances in dialysis and renal transplantation, the management of CKD remains largely supportive, with limited options to halt disease progression. High treatment costs and poor accessibility in low- and middle-income countries further add to the burden. Ayurveda, with its holistic principles, Rasayana therapy, and nephroprotective herbs, offers potential complementary strategies. Thus, an integrative approach combining modern nephrology with Ayurvedic interventions may improve patient outcomes and quality of life. n Ayurveda, CKD can be understood in relation to Mutravaha Srotas dushti involving Vata, Pitta, and Kapha, leading to progressive Dhatukshaya and Ojakshaya. The Samprapti is mainly due to Avarana of Vata by Kapha and Meda, resulting in deranged urine formation and systemic complications. Ayurvedic therapeutics emphasize Nidana Parivarjana, Shodhana (Basti, Virechana), and Shamana with nephroprotective herbs like Punarnava, Gokshura, Varuna, and Rasayana formulations to slow progression and improve quality of life.