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INTERNATIONAL JOURNAL OF CREATIVE RESEARCH THOUGHTS - IJCRT (IJCRT.ORG)

International Peer Reviewed & Refereed Journals, Open Access Journal

IJCRT Peer-Reviewed (Refereed) Journal as Per New UGC Rules.

ISSN Approved Journal No: 2320-2882 | Impact factor: 7.97 | ESTD Year: 2013

Call For Paper - Volume 14 | Issue 6 | Month- June 2026

Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 7.97 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(CrossRef DOI)

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  Published Paper Details:

  Paper Title

Hybrid CNN-Transformer Architecture for Automated Oral Lesion Analysis and Personalized Immunotherapy Prediction

  Authors

  Poornima S,  Dr.S.Gopinathan

  Keywords

Keywords Oral Lichen Planus; Deep Learning; CNN-Transformer; Lesion Segmentation; Multimodal Fusion; Immunotherapy Prediction; Personalized Medicine

  Abstract


Oral Lichen Planus (OLP) is a chronic inflammatory disorder affecting the oral mucosa, with diverse clinical presentations and a risk of malignant transformation. Early and precise assessment of lesions, along with prediction of immunotherapy outcomes, is critical for personalized patient care. Manual evaluation is time-intensive and prone to variability among clinicians. In this study, we introduce a hybrid deep learning framework that combines Convolutional Neural Networks (CNNs) for detailed spatial feature extraction with Transformer modules for capturing long-range contextual information. A multimodal fusion strategy further integrates lesion imaging features with patient-specific clinical data to predict individualized therapy responses. Experiments on a curated oral lesion dataset demonstrate that our approach achieves superior segmentation accuracy and predictive performance compared to existing baseline models. The framework offers a reproducible, interpretable, and automated tool to support precision oral healthcare and data-driven treatment planning.

  IJCRT's Publication Details

  Unique Identification Number - IJCRT2511041

  Paper ID - 295954

  Page Number(s) - a386-a394

  Pubished in - Volume 13 | Issue 11 | November 2025

  DOI (Digital Object Identifier) -   

  Publisher Name - IJCRT | www.ijcrt.org | ISSN : 2320-2882

  E-ISSN Number - 2320-2882

  Cite this article

  Poornima S,  Dr.S.Gopinathan,   "Hybrid CNN-Transformer Architecture for Automated Oral Lesion Analysis and Personalized Immunotherapy Prediction", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.13, Issue 11, pp.a386-a394, November 2025, Available at :http://www.ijcrt.org/papers/IJCRT2511041.pdf

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Call For Paper June 2026
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ISSN and 7.97 Impact Factor Details


ISSN
ISSN
ISSN: 2320-2882
Impact Factor: 7.97 and ISSN APPROVED
Journal Starting Year (ESTD) : 2013
ISSN
ISSN and 7.97 Impact Factor Details


ISSN
ISSN
ISSN: 2320-2882
Impact Factor: 7.97 and ISSN APPROVED
Journal Starting Year (ESTD) : 2013
ISSN
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