Published Paper Details:

Ocular drug delivery is one of the most challenging tasks faced by Pharmaceutical researchers. Major barriers in ocular medication are the ability to maintain a therapeutic level of the drug at the site of action for a prolonged duration. The ophthalmic preparations are available as sterile, buffered, isotonic solution. Several types of dosage forms are applied as the delivery system for the ocular delivery of drugs. The most prescribed dosage form is the eye drop solution as drops are easier to administer. Suspensions, gelled systems, ointment are also used for prolonged therapeutic action. Solvent casting technique was used to prepare the ocuserts. Ten formulation were prepared by using propranolol drug, cocos nucifera as biopolymer . The ocuserts were physically examined for colour and various other physical parameters were evaluated. Based on the physical parameters further studies were carried out like stability, invitro release studies. The therapeutic efficacy of an ocular drug can be greatly improved by prolonging its contact with the corneal surface. Newer ocular drug delivery systems are being explored to develop extended duration and controlled release strategy.