Published Paper Details:

"Medicinal Values In Gene Therapy using Gene Bombardment" Author1:-Pragya Aditya Asst.Prof.Ramshobha college of Education Ramgarh Author2:-Suniti Bala chandra Asst.Prof.Ramshobha college of Education Ramgarh Abstract Gene therapy has emerged as a promising approach for treating genetic disorders by directly modifying or correcting defective genes. Among the various gene delivery methods, gene bombardment (also known as biolistic transformation or particle bombardment) has gained importance due to its ability to introduce genetic material into target cells without the need for biological carriers. In this method, high-velocity microprojectiles coated with DNA are propelled into cells, enabling stable and efficient gene transfer. Gene bombardment offers several advantages such as applicability to a wide range of cell types, bypassing vector-related limitations, and reduced risk of immune reactions compared to viral delivery systems. Its potential in gene therapy lies in delivering therapeutic genes into somatic cells for the treatment of inherited diseases, cancers, and metabolic disorders. Although challenges such as limited penetration depth, possible cell damage, and lower efficiency compared to viral vectors remain, advancements in nanotechnology and delivery optimization are enhancing its feasibility. Thus, gene bombardment represents a significant non-viral strategy in the field of gene therapy, opening new avenues for safe and targeted treatment of genetic diseases. Keyword :-Gene Bombardmen, Gene therapy, Microprojection,nanotechnology, metabolic