Published Paper Details:

Melasma is a chronic skin condition marked by hyperpigmented patches, commonly triggered by hormonal fluctuations, sun exposure, and genetic predisposition1. While conventional treatments - such as hydroquinone and retinoid are effective, their prolonged use is often limited by side effects including irritation, rebound hyperpigmentation, and skin thinning2 . In recent years, herbal creams formulated with novel plant-based extracts have emerged as a promising alternative for the topical management of melasma3. These formulations leverage the natural tyrosinase-inhibitory, antioxidant, and anti-inflammatory properties of bioactive compounds found in herbs like Bakuchiol (Psoralea corylifolia)4 ,Glabridin from Licorice (Glycyrrhiza glabra)5, Alpha-arbutin from Bearberry (Arctostaphylos uva-ursi)6, Mulberry extract7 and Kojic acid-producing fungi-derived botanicals8. Incorporated into emulsion-based creams, these activities not only reduce melanin synthesis but also enhance skin tone uniformity with minimal irritation9.