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STATEMENT OF THE PROBLEM: "A study to assess knowledge regarding effects of substance abuse on health among adolescent students at the selected senior secondary school in Anupgarh district with a view to develop an informational booklet.'' OBJECTIVES OF THE STUDY 1. To assess the knowledge regarding effects of substance abuse on health among adolescent students of the selected senior secondary school in Anupgarh district. 2. To find out the significant association of knowledge regarding effects of substance abuse on health with their selected demographic variables. 3. To develop an information booklet regarding effects of substance abuse on health for adolescent students of the selected senior secondary school in Anupgarh district RESEARCH METHODOLOGY: A descriptive approach was used for this study. The study was carried out among adolescent students at the selected senior secondary school in Anupgarh district. The research design was descriptive research design. The sample comprised of total 100 adolescent students at the selected senior secondary school were selected by convenience sampling technique. MAJOR FINDINGS OF THE STUDY: o The study found a significant association between adolescents' knowledge of substance abuse and their age (?2=16.466) and educational standard (?2=6.9015) at the 0.05 level of significance, supporting the research hypothesis (H1). However, no significant association was found with gender, family type, area of residence, substance abuse in the family, or family income, leading to the acceptance of the null hypothesis (H0). This suggests that age and education level influence knowledge, while other demographic factors do not. Targeted educational interventions can enhance awareness among adolescents. o There was significant association between knowledge of adolescents and their socio- demographic variables such as Age (?2= 16.466) and educational standard (?2= 6.9015), at 0.05 level of significance. Hence the research hypothesis H1was accepted and null hypothesis H01 was rejected. o There was no significant association between knowledge of adolescents and their socio-demographic variables such as gender (?2= 0.1825), Type of Family (?2=1.9444), Area of residence (?2= 1.444) Substance abuse in family (?2= 0.2962) and family income (monthly) (?2=7.9524), at 0.05 level of significance. Hence the research hypothesis H1was rejected and null hypothesis H01was accepted. o The findings highlight that a significant portion of the adolescent population possesses good knowledge about substance abuse. However, gaps remain in certain areas, particularly among specific socio-demographic groups. The association of knowledge levels with variables such as age and educational standard suggests the need for targeted interventions. The study's results affirm the relevance and reliability of the research tool used CONCLUSION The following conclusions were drawn on the basis of the findings of the study. Majority (63%) had good knowledge, 36% had average knowledge, and only 1% had poor knowledge. Significant associations were observed between the level of knowledge and certain socio-demographic variables, such as age and educational standard. Most students were from urban areas, belonged to nuclear families, and had no history of substance abuse in their families. Age and education level significantly influence students' knowledge about substance abuse. Other demographic factors, including gender, family type, and residence, do not play a significant role. The study suggests focusing on educational interventions to improve awareness among younger students and those in lower grades.