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Thyroid disorders have been one among the most challenging and most common endocrine disorders that we confront worldwide. Major thyroid disorders,including Hypothyroidism, Hyperthyroidism, goitre/iodine deficiency, Hashimoto's thyroiditis, and thyroid cancer. Among these, hypothyroidism is arguably the most challenging as its multifarious clinical presentation often goes unnoticed. Hypothyroidism can be attributed to the deficiency of thyroid hormones, triiodothyronine (T3) and thyroxine (T4) in the body. Mild or subclinical hypothyroidism refers to the condition where peripheral thyroid hormone levels are within normal range, but serum thyroid-stimulating hormone (TSH) levels are mildly elevated. Hypothyroidism refers to the pathological state of thyroid hormone insufficiency.Most common symptoms of hypothyroidism include tiredness, constipation, weight gain, aches, dry hair, and skin and cold sensitivity along with being in a hypometabolic state. Due to the large variation in clinical manifestation and lack of warning signs, the characterization of hypothyroidism is, for the most part, biochemical.1 Overt or clinical primary hypothyroidism is said to be having the thyroid-stimulating hormone (TSH) concentrations higher and free thyroid hormone (T3/T4) concentrations less than the reference range. Mild or subclinical hypothyroidism is characterized by TSH concentrations exceeding the reference range whereas the free thyroxine concentrations remain within the normal range2. This is commonly regarded as a sign of early thyroid failure. According to others, hypothyroidism can be subdivided into primary, secondary, or tertiary, and central and peripheral hypothyroidism. The primary hypothyroidism is the result of the lack of active thyroid hormones in the system. Secondary hypothyroidism results from the deficiency of TSH, whereas tertiary type is brought about by the thyrotropin-releasing hormone (TRH) deficiency that actually results in reduced TSH release. The central and peripheral hypothyroidism, having characteristic reasons, is accounted for less than 1% of all cases throughout the world.