Published Paper Details:

Thyroid disorders, encompassing hypothyroidism and hyperthyroidism, are critical global health challenges that significantly impact metabolic and systemic functions. This review decisively examines both established and innovative therapeutic strategies for managing these conditions, with a particular emphasis on treatments for hypothyroidism and hyperthyroidism. For hypothyroidism, levothyroxine tablets are the gold standard therapy, delivering reliable hormone replacement. Combination therapy using levothyroxine and liothyronine is an effective alternative for patients who continue to experience symptoms despite standard treatment. Furthermore, novel delivery methods, including soft gel and liquid formulations, as well as injectable and rectal preparations of levothyroxine, have been successfully developed to address specific patient needs, such as enhanced bio availability and absorption. Emerging therapeutic systems, such as implantable drug delivery technologies are poised to revolutionize treatment adherence and ensure precise hormone release. In the realm of hyperthyroidism management, traditional antithyroid drug therapies serve as the cornerstone of treatment. Rectal administration of these drugs provides a practical option for patients unable to tolerate oral medications. Additionally, injectable formulations offer vital flexibility in clinical management, particularly for acute cases. This paper deliberates the latest advancements in both standard and alternative therapies, firmly highlighting the evolving landscape of thyroid disorder management. It aims to inform clinicians and researchers about cutting-edge approaches to optimize patient care, effectively addressing gaps in current therapeutic practices for hypothyroidism and hyperthyroidism.