Published Paper Details:

The genus Zingiberaceae has been widely used for phytotherapeutic purposes in traditional medicine throughout the world for its anti-inflammatory activity. Experimental studies have established that inflammation caused by chronic infections represents a risk factor for different forms of cancer. The objective of this study was focused on determining the anti-inflammatory capacity and cytotoxic activity of aqueous extracts of Elettaria cardamomum (cardamom) . Herbal suppositories offer an effective alternative to conventional drug delivery, particularly for localized treatment of rectal conditions such as hemorrhoids, inflammation, and infections. Cardamom (*Elettaria cardamomum) possesses significant anti-inflammatory, antimicrobial, and antioxidant properties, making it a promising candidate for suppository formulation. Cardamom (Elettaria cardamomum) exhibits significant anti-inflammatory properties through multiple mechanisms, making it a promising therapeutic agent for inflammatory conditions. Studies demonstrate that cardamom extracts reduce pro-inflammatory cytokines. In vivo studies show cardamom's efficacy in reducing carrageenan-induced paw edema and tamoxifen-induced liver damage by attenuating oxidative stress and pyroptosis markers Clinical applications include its use in periodontal infections due to antibacterial and anti-inflammatory synergy Cardamom's safety is evidenced by its non-cytotoxic profile in cell lines . These findings highlight its potential as a multifunctional anti-inflammatory agent for both preventive and therapeutic interventions. This abstract integrates key findings from the search results, emphasizing mechanisms, bioactive components, and clinical relevance. Let me know if you'd like to focus on specific aspects (e.g., molecular pathways or clinical studies) for further detail.