Published Paper Details:

Fast-dissolving tablets are becoming one of the most common and widely recognized dosage forms, particularly for juvenile patients due to their immature neurological and muscular systems and elderly patients with hand tremors or Parkinson's disease. There are currently few solid dose forms, such as tablets and capsules, that do not have issues like dysphagia, which makes the therapy inefficient and leads to numerous instances of non-compliance. In addition to being the most popular method of administering many medications, oral dosage forms and routes have drawbacks, such as first-pass metabolism, mental patients, immobile patients, and difficult patients. Real fast-dissolving pills are made to dissolve in saliva amazingly quickly--within a few seconds, that is, less than 60 seconds.FDTs formulations contain super disintegrants to enhance the disintegration rate of a tablet in the buccal cavity FDT formulations contain super disintegrants, which increase a tablet's disintegration rate in the buccal cavity. FDTs have several advantages, including easy mobility and manufacture, accurate dosing, strong chemical and physical stability, and are an excellent choice for elderly and pediatric patients. FDTs dissolve swiftly and absorb faster, reducing in vitro drug release time and increasing bioavailability. FDT formulations combine the benefits of both traditional tablet formulation and liquid dose form. Several conventional or patented technologies for FDT production have been developed, including spray drying, cotton candy process, sublimation, melt granulation, direct compression freezing drying/lyophilization, phase transition process, mass extrusion, and so on. This review contains brief information regarding FDTs, including definitions and advantages. This review contains basic information regarding FDTs, such as their definition, advantages, needs or requirements, noteworthy features, limits, obstacles in developing FDTs, marketed formulations of fast dissolving tablets.