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ISSN Approved Journal No: 2320-2882 | Impact factor: 7.97 | ESTD Year: 2013
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Paper Title
FORMULATION AND EVALUATION OF ONDANSETRON HYDROCHLORIDE TABLETS USING NATURAL DISINTEGRATING AGENT
Authors
Pratik B. Aru, Nandakishor B. Deshmukh, Swati P. Deshmukh
Keywords
Ondansetron Hydrochloride, Orodispersible Tablets, Acacia gum, Natural Disintegrant, Drug Release, Mucoadhesive Delivery
Abstract
The present study focuses on the formulation and evaluation of Ondansetron Hydrochloride orodispersible tablets utilizing Acacia gum as a natural superdisintegrant. Natural disintegrants are gaining popularity due to their biocompatibility, non-toxicity, and cost-effectiveness. In this work, various formulations were prepared using direct compression, incorporating different concentrations of Acacia gum, and evaluated for pre-compression and post-compression parameters such as hardness, friability, disintegration time, and drug release. Among the formulations, batch F3 exhibited the best performance with a disintegration time of 22 seconds and 99.31% drug release at 30 minutes. The findings suggest that Acacia gum can serve as an effective and natural alternative to synthetic superdisintegrants in the development of fast-dissolving tablets.
IJCRT's Publication Details
Unique Identification Number - IJCRT2505265
Paper ID - 285011
Page Number(s) - c337-c354
Pubished in - Volume 13 | Issue 5 | May 2025
DOI (Digital Object Identifier) -
Publisher Name - IJCRT | www.ijcrt.org | ISSN : 2320-2882
E-ISSN Number - 2320-2882
Cite this article
Pratik B. Aru, Nandakishor B. Deshmukh, Swati P. Deshmukh, "FORMULATION AND EVALUATION OF ONDANSETRON HYDROCHLORIDE TABLETS USING NATURAL DISINTEGRATING AGENT", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.13, Issue 5, pp.c337-c354, May 2025, Available at :http://www.ijcrt.org/papers/IJCRT2505265.pdf
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Volume 14 | Issue 3
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Submit Manuscript Online Impact Factor: 7.97 Review Results : Within 02-03 Days Paper Publication : Within 02-03 Days
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
ISSN and 7.97 Impact Factor Details
ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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