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  Published Paper Details:

  Paper Title

Negative Effect of Nickel Chloride Intake on Red Blood Cell Count in Mus musculus

  Authors

  Sneha Priya,  Dr. Ashok Kumar Thakur

  Keywords

Keywords: Nickel chloride, hematotoxicity, red blood cells, anemia, Mus musculus, heavy metal toxicity

  Abstract


Nickel chloride (NiCl?) is an environmental pollutant known for its toxicological effects on various biological systems. This study investigates the negative impact of NiCl? intake on red blood cell (RBC) count in Mus musculus. Twenty male mice were divided into two groups: a control group (n = 10) receiving distilled water and a treated group (n = 10) administered NiCl? at a dose of 13.6 mg/kg body weight for 35 days. Blood samples were collected at the end of the experimental period to determine RBC count. Statistical analysis was conducted to compare the mean RBC values between the groups. The results demonstrated a significant reduction (p < 0.05) in RBC count in the NiCl?-treated group compared to the control, indicating hematotoxicity. These findings suggest that chronic exposure to nickel chloride adversely affects erythropoiesis, potentially leading to anemia. Further studies are recommended to explore the underlying mechanisms of nickel-induced hematotoxicity and its long-term health implications.

  IJCRT's Publication Details

  Unique Identification Number - IJCRT2504470

  Paper ID - 281321

  Page Number(s) - e16-e22

  Pubished in - Volume 13 | Issue 4 | April 2025

  DOI (Digital Object Identifier) -   

  Publisher Name - IJCRT | www.ijcrt.org | ISSN : 2320-2882

  E-ISSN Number - 2320-2882

  Cite this article

  Sneha Priya,  Dr. Ashok Kumar Thakur,   "Negative Effect of Nickel Chloride Intake on Red Blood Cell Count in Mus musculus", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.13, Issue 4, pp.e16-e22, April 2025, Available at :http://www.ijcrt.org/papers/IJCRT2504470.pdf

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ISSN: 2320-2882
Impact Factor: 7.97 and ISSN APPROVED
Journal Starting Year (ESTD) : 2013
ISSN
ISSN and 7.97 Impact Factor Details


ISSN
ISSN
ISSN: 2320-2882
Impact Factor: 7.97 and ISSN APPROVED
Journal Starting Year (ESTD) : 2013
ISSN
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