Published Paper Details:

Inflammation is a complex biological response to harmful stimuli, playing a crucial role in various diseases, including autoimmune disorders, cardiovascular conditions, and neurodegenerative diseases. Medicinal plants have long been a source of bioactive compounds with anti-inflammatory properties, offering promising alternatives to synthetic drugs. This review explores the molecular mechanisms through which plant-derived compounds, such as flavonoids, alkaloids, phenolic acids, and terpenoids, modulate inflammatory pathways. Special emphasis is placed on their interaction with key inflammatory mediators, including cytokines, transcription factors, and eicosanoids. Additionally, the classification and mechanisms of non-steroidal anti-inflammatory drugs (NSAIDs) are discussed to highlight the potential of phytochemicals in developing novel anti-inflammatory therapies. By integrating traditional knowledge with modern pharmacological advancements, plant-based compounds present an innovative approach to inflammation management, warranting further research and clinical validation.